Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors.
暂无分享,去创建一个
B. Druker | N. Lydon | E. Buchdunger | D. Stover | E. Buchdunger | C. Cioffi | N. Law | S. Ohno-Jones | N. M. Law | Sayuri Ohno-Jones
[1] S. Honsawek,et al. The selective tyrosine kinase inhibitor STI571 inhibits small cell lung cancer growth. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[2] E. Buchdunger,et al. Role of platelet-derived growth factor in obliterative bronchiolitis (chronic rejection) in the rat. , 1999, American journal of respiratory and critical care medicine.
[3] C. Moskaluk,et al. Activating c-kit gene mutations in human germ cell tumors. , 1999, The American journal of pathology.
[4] D. Heitjan,et al. Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[5] S. Hirota,et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. , 1998, Science.
[6] M. Carroll,et al. CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins. , 1997, Blood.
[7] S. Hirota,et al. Ultrastructural identification of the c-kit-expressing interstitial cells in the rat stomach: a comparison of control and Ws/Ws mutant rats , 1997, Cell and Tissue Research.
[8] Jürg Zimmermann,et al. Potent and selective inhibitors of the Abl-kinase: phenylamino-pyrimidine (PAP) derivatives , 1997 .
[9] Jürg Zimmermann,et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells , 1996, Nature Medicine.
[10] G. Krystal,et al. Autocrine growth of small cell lung cancer mediated by coexpression of c-kit and stem cell factor. , 1996, Cancer research.
[11] G. Krystal,et al. Coexpression of the c-kit and stem cell factor genes in breast carcinomas. , 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[12] C. Heldin,et al. Dimerization of cell surface receptors in signal transduction , 1995, Cell.
[13] R. Ross,et al. Growth Regulatory Mechanisms and Formation of the Lesions of Atherosclerosis a , 1994, Annals of the New York Academy of Sciences.
[14] I. Mcniece,et al. Stem cell factor. , 1995, Journal of leukocyte biology.
[15] H. Inui,et al. Differences in signal transduction between platelet-derived growth factor (PDGF) alpha and beta receptors in vascular smooth muscle cells. PDGF-BB is a potent mitogen, but PDGF-AA promotes only protein synthesis without activation of DNA synthesis. , 1994, The Journal of biological chemistry.
[16] S. Sartore,et al. Smooth-muscle-cell proliferation and differentiation in neointima formation and vascular restenosis. , 1994, Clinical science.
[17] S. Kyo,et al. Coexpression of the c-kit receptor and the stem cell factor in gynecological tumors. , 1994, Cancer research.
[18] N. Lydon,et al. 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[19] C. Heldin,et al. Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[20] R. Nakhleh,et al. Obliterative bronchiolitis after lung transplantation: a fibroproliferative disorder associated with platelet-derived growth factor. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[21] K. Zsebo,et al. Nonhematopoietic tumor cell lines express stem cell factor and display c-kit receptors. , 1992, Blood.
[22] E. Thiel,et al. Recombinant human stem cell factor stimulates growth of a human glioblastoma cell line expressing c-kit protooncogene. , 1992, Cancer research.
[23] C. Heldin,et al. Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops. , 1992, Cancer research.
[24] D. Gordon. Growth factors and cell proliferation in human transplant arteriosclerosis. , 1992, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
[25] T Takahashi,et al. Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer. , 1991, Oncogene.
[26] M. Reidy,et al. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF , 1991, Science.
[27] R. Ueda,et al. Preferential expression of c-kit protooncogene transcripts in small cell lung cancer. , 1991, Cancer research.
[28] A. Ullrich,et al. Expression of the hst-1 and c-kit protooncogenes in human testicular germ cell tumors. , 1991, Cancer research.
[29] K. Zsebo,et al. Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3 and epo to stimulate human progenitor cells of the myeloid and erythroid lineages. , 1991, Experimental hematology.
[30] L. Cantley,et al. The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase , 1989, Nature.
[31] A. Bernstein,et al. Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice. , 1989, Genes & development.
[32] C. Heldin,et al. Rat brain capillary endothelial cells express functional PDGF B-type receptors. , 1989, Growth factors.
[33] Jonathan A. Cooper,et al. Different effects of homo‐ and heterodimers of platelet‐derived growth factor A and B chains on human and mouse fibroblasts. , 1988, The EMBO journal.
[34] C. Heldin,et al. Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types. , 1988, The EMBO journal.
[35] H. Antoniades,et al. Constitutive production of platelet-derived growth factor-like proteins by human prostate carcinoma cell lines. , 1988, Cancer research.
[36] C. Heldin,et al. Frequent expression of growth factors for mesenchymal cells in human mammary carcinoma cell lines. , 1987, Cancer research.
[37] Gary R. Grotendorst,et al. Platelet-derived growth factor in chemotactic for fibroblasts , 1982, The Journal of cell biology.