In vitro and in vivo characterization of the multiple isoforms of Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferases.
暂无分享,去创建一个
R. Owens | L. Bird | J. Brandão-Neto | J. Nettleship | Yamini Reddivari | R. DeMarco | A. E. Zeraik | H. Pereira | V. Serrão | Heather Rada | J. R. Torini | L. Romanello | Adriano de Freitas Fernandes
[1] R. Owens,et al. The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs , 2018, bioRxiv.
[2] A. Cassago,et al. Schistosoma mansoni displays an adenine phosphoribosyltransferase preferentially expressed in mature female gonads and vitelaria. , 2017, Molecular and biochemical parasitology.
[3] R. Owens,et al. Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL). , 2017, Molecular and biochemical parasitology.
[4] J. Brandão-Neto,et al. Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5’-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway , 2016, PLoS neglected tropical diseases.
[5] Graeme Winter,et al. Decision making in xia2 , 2013, Acta crystallographica. Section D, Biological crystallography.
[6] J. Brandão-Neto,et al. Adenosine kinase from Schistosoma mansoni: structural basis for the differential incorporation of nucleoside analogues. , 2013, Acta crystallographica. Section D, Biological crystallography.
[7] R. DeMarco,et al. Structural and kinetic studies of Schistosoma mansoni adenylate kinases. , 2012, Molecular and biochemical parasitology.
[8] L. Bird. High throughput construction and small scale expression screening of multi-tag vectors in Escherichia coli. , 2011, Methods.
[9] J. Collins,et al. Whole mount in situ hybridization methodology for Schistosoma mansoni. , 2011, Molecular and biochemical parasitology.
[10] Randy J. Read,et al. Overview of the CCP4 suite and current developments , 2011, Acta crystallographica. Section D, Biological crystallography.
[11] Vincent B. Chen,et al. Correspondence e-mail: , 2000 .
[12] V. Berdini,et al. Crystal structure of Schistosoma purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor. , 2009, Acta tropica.
[13] G. Oliva,et al. Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni. , 2010, Acta crystallographica. Section D, Biological crystallography.
[14] Í. Lopes-Cendes,et al. Schistosoma mansoni: evaluation of an RNAi-based treatment targeting HGPRTase gene. , 2008, Experimental parasitology.
[15] Rodrigo Lopez,et al. Clustal W and Clustal X version 2.0 , 2007, Bioinform..
[16] S. Trapani,et al. Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase , 2007, BMC Structural Biology.
[17] C. Caffrey,et al. Chemotherapy of schistosomiasis: present and future. , 2007, Current opinion in chemical biology.
[18] Randy J. Read,et al. Phaser crystallographic software , 2007, Journal of applied crystallography.
[19] David Alderton,et al. A versatile ligation-independent cloning method suitable for high-throughput expression screening applications , 2007, Nucleic acids research.
[20] G. Dillon,et al. Patterns of gene expression in schistosomes: localization by whole mount in situ hybridization , 2007, Parasitology.
[21] Alan Fenwick,et al. Schistosomiasis: challenges for control, treatment and drug resistance , 2006, Current opinion in infectious diseases.
[22] Jeffrey D Sachs,et al. Incorporating a Rapid-Impact Package for Neglected Tropical Diseases with Programs for HIV/AIDS, Tuberculosis, and Malaria , 2006, PLoS medicine.
[23] P. Evans,et al. Scaling and assessment of data quality. , 2006, Acta crystallographica. Section D, Biological crystallography.
[24] G. Franco,et al. Structures for the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni causal agent of schistosomiasis. , 2005, Journal of molecular biology.
[25] Ming Luo,et al. Alternative IMP binding in feedback inhibition of hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcongensis. , 2005, Journal of molecular biology.
[26] Kevin Cowtan,et al. research papers Acta Crystallographica Section D Biological , 2005 .
[27] P. Focia,et al. Interactions at the dimer interface influence the relative efficiencies for purine nucleotide synthesis and pyrophosphorolysis in a phosphoribosyltransferase. , 2004, Journal of molecular biology.
[28] J. McKerrow,et al. Schistosoma mansoni: sex-specific modulation of parasite growth by host immune signals. , 2004, Experimental parasitology.
[29] J. Habbema,et al. Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa. , 2003, Acta tropica.
[30] Randy J Read,et al. Electronic Reprint Biological Crystallography Phenix: Building New Software for Automated Crystallographic Structure Determination Biological Crystallography Phenix: Building New Software for Automated Crystallographic Structure Determination , 2022 .
[31] L. Guddat,et al. Crystal structures of free, IMP‐, and GMP‐bound Escherichia coli hypoxanthine phosphoribosyltransferase , 2002, Protein science : a publication of the Protein Society.
[32] C. Bashor,et al. The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[33] W. Delano. The PyMOL Molecular Graphics System , 2002 .
[34] John P. Huelsenbeck,et al. MRBAYES: Bayesian inference of phylogenetic trees , 2001, Bioinform..
[35] P. Focia,et al. The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography. , 2001, Biochemistry.
[36] D. Borhani,et al. Crystal structures of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase-GMP and -IMP complexes: comparison of purine binding interactions with the XMP complex. , 1999, Biochemistry.
[37] R. Furneaux,et al. The 2.0 Å structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor , 1999, Nature Structural Biology.
[38] Yiming Xu,et al. Ternary complex structure of human hgprtase, prpp, mg2+, and the inhibitor HPP reveals the involvement of the flexible loop in substrate binding , 1999, Protein science : a publication of the Protein Society.
[39] P. Focia,et al. Approaching the transition state in the crystal structure of a phosphoribosyltransferase. , 1998, Biochemistry.
[40] R. Fletterick,et al. A 1.4 A crystal structure for the hypoxanthine phosphoribosyltransferase of Trypanosoma cruzi. , 1998, Biochemistry.
[41] R. Fletterick,et al. Crystal structure of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from the protozoan parasite Tritrichomonas foetus. , 1996, Biochemistry.
[42] James C. Sacchettini,et al. The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP , 1994, Cell.
[43] T. Allen,et al. Molecular characterization and overexpression of the hypoxanthine-guanine phosphoribosyltransferase gene from Trypanosoma cruzi. , 1994, Molecular and biochemical parasitology.
[44] 玉一 芦田,et al. Acta Crystallographica Section D (Biological Crystallography) の発刊に際して , 1993 .
[45] C. Wang,et al. Comparing the human and schistosomal hypoxanthine-guanine phosphoribosyltransferases by circular dichroism. , 1993, Biochimica et biophysica acta.
[46] C. Wang,et al. Steady-state kinetics of the schistosomal hypoxanthine-guanine phosphoribosyltransferase. , 1992, Biochemistry.
[47] C. Wang,et al. Analysis of cDNA encoding the hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) of Schistosoma mansoni; a putative target for chemotherapy. , 1988, Nucleic acids research.
[48] C. Wang,et al. Purification and characterization of hypoxanthine-guanine phosphoribosyltransferase from Schistosoma mansoni. A potential target for chemotherapy. , 1986, The Journal of biological chemistry.
[49] C. Wang,et al. Purine salvage in Schistosoma mansoni schistosomules. , 1984, Molecular and biochemical parasitology.
[50] A. W. Senft,et al. Purine metabolism in the schistosomes: potential targets for chemotherapy. , 1983, Pharmacology & therapeutics.
[51] J. Richardson,et al. The anatomy and taxonomy of protein structure. , 1981, Advances in protein chemistry.
[52] B. Migeon,et al. Human and mouse hypoxanthine-guanine phosphoribosyltransferase: dimers and tetramers. , 1979, Science.
[53] A. W. Senft,et al. Pathways of nucleotide metabolism in Schistosoma mansoni--VII. Inhibition of adenine and guanine nucleotide synthesis by purine analogs in intact worms. , 1977, Biochemical pharmacology.
[54] A. W. Senft,et al. Pathways of nucleotide metabolism in Schistosoma mansoni--VI adenosine phosphorylase. , 1975, Biochemical pharmacology.
[55] A. W. Senft,et al. Pathways of nucleotide metabolism in schistosoma mansoni. V. Adenosine cleavage enzyme and effects of purine analogues on adenosine metabolism in vitro. , 1974, Biochemical pharmacology.
[56] A. W. Senft,et al. Pathways of nucleotide metabolism in Schistosoma mansoni. II. Disposition of adenosine by whole worms. , 1973, Biochemical pharmacology.
[57] A. W. Senft,et al. Pathways of nucleotide metabolism in Schistosoma mansoni. 3. Identification of enzymes in cell-free extracts. , 1973, Biochemical pharmacology.
[58] A. W. Senft,et al. Pathways of nucleotide metabolism in Schistosoma mansoni. IV. Incorporation of adenosine analogs in vitro. , 1973, Biochemical pharmacology.
[59] A. W. Senft,et al. Purine metabolism in Schistosoma mansoni. , 1972, International journal for parasitology.