Large‐Scale Production of Homogeneous Helical Amylose/SWNTs Complexes with Good Biocompatibility

The key to developing novel applications of SWNTs in biotechnology and biomedicine is to improve their biocompatibility and solubility in water and to assemble them into useful architectures. We describe how amylose can help to solubilize SWNTs and wrap around SWNTs into helical superstructures with periodic pitch. FT-IR, Raman spectroscopy, 1 H NMR and HR-TEM are used to confirm the generation of amylose/ SWNTs complexes (A/S-C). It is demonstrated that most of the A/S-C have similar diameters (ca. 20-30 nm) and a helical morphology with a pitch of ca. 14 nm. A test of Hela cell viability revealed that the A/S-C had much better biocompatibility than SWNTs.

[1]  Hyoun-woo Kim,et al.  Helical nanostructures of SiOx synthesized through the heating of Co-coated substrates , 2007 .

[2]  M. Drew,et al.  Formation of triple helical nanofibers using self-assembling chiral benzene-1,3,5-tricarboxamides and reversal of the nanostructure's handedness using mirror image building blocks. , 2006, Chemical communications.

[3]  C. Grigoropoulos,et al.  Fast Mass Transport Through Sub-2-Nanometer Carbon Nanotubes , 2006, Science.

[4]  Yonggang Yang,et al.  Control of helical silica nanostructures using a chiral surfactant , 2006 .

[5]  A. Alivisatos,et al.  Continuous distribution of emission states from single CdSe/ZnS quantum dots. , 2006, Nano letters.

[6]  Ravi S Kane,et al.  Protein-assisted solubilization of single-walled carbon nanotubes. , 2006, Langmuir : the ACS journal of surfaces and colloids.

[7]  Robert M Shelby,et al.  Sequence-independent helical wrapping of single-walled carbon nanotubes by long genomic DNA. , 2006, Nano letters.

[8]  H. Byrne,et al.  Interaction of Carbon Nanotubes with Sugar Complexes , 2005 .

[9]  V. C. Moore,et al.  Visualization of individual single-walled carbon nanotubes by fluorescent polymer wrapping. , 2005, Nano letters.

[10]  A. Soh,et al.  Investigation of non-covalent association of single-walled carbon nanotube with amylose by molecular dynamics simulation , 2005 .

[11]  K. Sakurai,et al.  Inclusion of cut and as-grown single-walled carbon nanotubes in the helical superstructure of schizophyllan and curdlan (beta-1,3-glucans). , 2005, Journal of the American Chemical Society.

[12]  A. Dalton,et al.  Hierarchical Self‐Assembly of Peptide‐Coated Carbon Nanotubes , 2004 .

[13]  Ray H Baughman,et al.  Preparation and characterization of individual peptide-wrapped single-walled carbon nanotubes. , 2004, Journal of the American Chemical Society.

[14]  M. Dresselhaus,et al.  Structure-Based Carbon Nanotube Sorting by Sequence-Dependent DNA Assembly , 2003, Science.

[15]  Hugh J. Byrne,et al.  Characterization of the interaction of gamma cyclodextrin with single-walled carbon nanotubes , 2003 .

[16]  J. Baldwin,et al.  Solubilization of single-wall carbon nanotubes by supramolecular encapsulation of helical amylose. , 2003, Journal of the American Chemical Society.

[17]  Ya‐Ping Sun,et al.  Solubilization of Single-Walled Carbon Nanotubes with Diamine-Terminated Oligomeric Poly(ethylene Glycol) in Different Functionalization Reactions , 2003 .

[18]  Fotios Papadimitrakopoulos,et al.  A route for bulk separation of semiconducting from metallic single-wall carbon nanotubes. , 2003, Journal of the American Chemical Society.

[19]  Edgar Muñoz,et al.  Controlled assembly of carbon nanotubes by designed amphiphilic Peptide helices. , 2003, Journal of the American Chemical Society.

[20]  Arjun G. Yodh,et al.  High Weight Fraction Surfactant Solubilization of Single-Wall Carbon Nanotubes in Water , 2003 .

[21]  V. C. Moore,et al.  Band Gap Fluorescence from Individual Single-Walled Carbon Nanotubes , 2002, Science.

[22]  James R Heath,et al.  Starched carbon nanotubes. , 2002, Angewandte Chemie.

[23]  A. Hirsch Functionalization of single-walled carbon nanotubes. , 2002, Angewandte Chemie.

[24]  P. Poulin,et al.  Macroscopic fibers and ribbons of oriented carbon nanotubes. , 2000, Science.

[25]  Hugh J. Byrne,et al.  Selective interaction of a semiconjugated organic polymer with single-wall nanotubes , 2000 .

[26]  S. Iijima Helical microtubules of graphitic carbon , 1991, Nature.