Macromonomer Purification Strategy for Well‐Defined Polymer Amphiphiles Incorporating Poly(ethylene glycol) Monomethacrylate

Commercial hydroxy-terminated poly(ethylene glycol) monomethacrylates (PEG-MAs) contain poly(ethylene glycol) dimethacrylate, which leads to unfavorable gel formation on polymerization. Here, hydroxy-terminated PEG-MA is readily isolated using a dimethylsilyl resin chlorinated with 1,3-dichloro-5,5-dimethylhydantoin. Solution polymerization of the isolated PEG-MA by free radical routes gives a high-molecular-weight amphiphilic graft copolymer without cross-linking. The resulting polymer is stable for long periods in ambient conditions with preservation of the hydroxy end groups of PEG.

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