Polymorphisms in pfcrt and pfmdr1: parasite risk factors that affect treatment outcomes for falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine-Corrected version
暂无分享,去创建一个
Billy | Badria B. El-Sayed | Catherine | Sabina | R. Price | F. Checchi | P. Rosenthal | A. Nzila | Cesar Arze | F. Nosten | J. Ouédraogo | S. Kariuki | B. Ogutu | A. Djimde | K. Stepniewska | D. Ménard | A. Mårtensson | C. Plowe | S. Nsobya | P. Guérin | P. Kofoed | Teferi Eshetu | T. Davis | M. Desai | S. Borrmann | P. Dahal | J. Faucher | B. Schramm | C. Sibley | J. Ursing | C. Sutherland | S. Houzé | M. Dhorda | M. Venkatesan | A. Zeynudin | I. Zongo | F. Kironde | N. Berens-Riha | Nahla B. Gadalla | M. Oguike | A. Björkman | F. N. Baliraine | Gabrielle Fröberg | P. Piola | Erasmus Kamugisha | Jacob D. Johnson | Dorsey | M. Malmberg | J. Thwing | L. Mwai | G. Ademowo | J. Kiechel | Lars | Prabin Dahal | Grant | A. Somé | Christian | Nsanzabana | Clarissa Moriera | Ishag | Adam | Frederick Eyase | Falade | Anastasia Grivoyannis | SallyHamour | J. Lebras | Ngasala | Dahlström Otienoburu | Rombo | Rina P. M. Wong | B. El-Sayed | N. Gadalla
[1] B. Genton,et al. A molecular marker of artemisinin-resistant Plasmodium falciparum malaria , 2013, Nature.
[2] Charles Akugbey Narh,et al. Increased pfmdr1 gene copy number and the decline in pfcrt and pfmdr1 resistance alleles in Ghanaian Plasmodium falciparum isolates after the change of anti-malarial drug treatment policy , 2013, Malaria Journal.
[3] R. Price,et al. Nonlinear Mixed-Effects Modelling of In Vitro Drug Susceptibility and Molecular Correlates of Multidrug Resistant Plasmodium falciparum , 2013, PloS one.
[4] E. Ashley,et al. Efficacy of artesunate-amodiaquine and artemether-lumefantrine fixed-dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria among children aged six to 59 months in Nimba County, Liberia: an open-label randomized non-inferiority trial , 2013, Malaria Journal.
[5] Andreas Mårtensson,et al. Plasmodium falciparum Drug Resistance Phenotype as Assessed by Patient Antimalarial Drug Levels and Its Association With pfmdr1 Polymorphisms , 2012, The Journal of infectious diseases.
[6] L. Quaye,et al. Therapeutic efficacy of artemether-lumefantrine combination in the treatment of uncomplicated malaria among children under five years of age in three ecological zones in Ghana , 2012, Malaria Journal.
[7] A. Wieser,et al. Open-label trial with artemether-lumefantrine against uncomplicated Plasmodium falciparum malaria three years after its broad introduction in Jimma Zone, Ethiopia , 2012, Malaria Journal.
[8] Kayla R. Stover,et al. Artemether-Lumefantrine: An Option for Malaria , 2012, The Annals of pharmacotherapy.
[9] F. Kironde,et al. Efficacy of artemether-lumefantrine in treatment of malaria among under-fives and prevalence of drug resistance markers in Igombe-Mwanza, north-western Tanzania , 2012, Malaria Journal.
[10] C. Happi,et al. In vitro amodiaquine resistance and its association with mutations in pfcrt and pfmdr1 genes of Plasmodium falciparum isolates from Nigeria. , 2011, Acta tropica.
[11] A. Nzila,et al. Declining Responsiveness of Plasmodium falciparum Infections to Artemisinin-Based Combination Treatments on the Kenyan Coast , 2011, PloS one.
[12] P. Rosenthal,et al. Prolonged selection of pfmdr1 polymorphisms after treatment of falciparum malaria with artemether-lumefantrine in Uganda. , 2011, The Journal of infectious diseases.
[13] Badria B. El-Sayed,et al. Increased pfmdr1 Copy Number and Sequence Polymorphisms in Plasmodium falciparum Isolates from Sudanese Malaria Patients Treated with Artemether-Lumefantrine , 2011, Antimicrobial Agents and Chemotherapy.
[14] F. Ou,et al. Randomized trials of artemisinin-piperaquine, dihydroartemisinin-piperaquine phosphate and artemether-lumefantrine for the treatment of multi-drug resistant falciparum malaria in Cambodia-Thailand border area , 2011, Malaria Journal.
[15] L. Ranford-Cartwright,et al. Rational deployment of antimalarial drugs in Africa: should first-line combination drugs be reserved for paediatric malaria cases? , 2011, Parasitology.
[16] M. Petzold,et al. Efficacy and effectiveness of artemether-lumefantrine after initial and repeated treatment in children <5 years of age with acute uncomplicated Plasmodium falciparum malaria in rural Tanzania: a randomized trial. , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[17] Z. Premji,et al. Effectiveness of artemether-lumefantrine provided by community health workers in under-five children with uncomplicated malaria in rural Tanzania: an open label prospective study , 2011, Malaria Journal.
[18] S. Ward,et al. Association between the pfmdr1 gene and in vitro artemether and lumefantrine sensitivity in Thai isolates of Plasmodium falciparum. , 2010, The American journal of tropical medicine and hygiene.
[19] R. Durand,et al. Chloroquine Clinical Failures in P. falciparum Malaria Are Associated with Mutant Pfmdr-1, Not Pfcrt in Madagascar , 2010, PloS one.
[20] Teferi Eshetu,et al. Different mutation patterns of Plasmodium falciparum among patients in Jimma University Hospital, Ethiopia , 2010, Malaria Journal.
[21] P. Rosenthal,et al. Selection of Known Plasmodium falciparum Resistance-Mediating Polymorphisms by Artemether-Lumefantrine and Amodiaquine- Sulfadoxine-Pyrimethamine but Not Dihydroartemisinin- Piperaquine in Burkina Faso , 2010, Antimicrobial Agents and Chemotherapy.
[22] O. Müller,et al. Selection of pfmdr1 and pfcrt alleles in amodiaquine treatment failure in north-western Burkina Faso. , 2010, Acta tropica.
[23] S. Krudsood,et al. The clinical efficacy of artemether/lumefantrine (Coartem®) , 2009, Malaria Journal.
[24] Paul Garner,et al. Artemisinin-based combination therapy for treating uncomplicated malaria. , 2009, The Cochrane database of systematic reviews.
[25] J. Vulule,et al. In‐vivo efficacy of amodiaquine‐artesunate in children with uncomplicated Plasmodium falciparum malaria in western Kenya , 2009, Tropical medicine & international health : TM & IH.
[26] Z. Premji,et al. In vivo selection of Plasmodium falciparum parasites carrying the chloroquine-susceptible pfcrt K76 allele after treatment with artemether-lumefantrine in Africa. , 2009, The Journal of infectious diseases.
[27] S. Meshnick,et al. Pfmdr1 copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia , 2009, Malaria Journal.
[28] D. Wirth,et al. Selection of Plasmodium falciparum Multidrug Resistance Gene 1 Alleles in Asexual Stages and Gametocytes by Artemether-Lumefantrine in Nigerian Children with Uncomplicated Falciparum Malaria , 2008, Antimicrobial Agents and Chemotherapy.
[29] David L. Smith,et al. Benefits of using multiple first-line therapies against malaria , 2008, Proceedings of the National Academy of Sciences.
[30] O. Ademowo,et al. High efficacy of two artemisinin‐based combinations (artemether–lumefantrine and artesunate plus amodiaquine) for acute uncomplicated malaria in Ibadan, Nigeria , 2008, Tropical medicine & international health : TM & IH.
[31] A. Dicko,et al. Efficacy, safety, and selection of molecular markers of drug resistance by two ACTs in Mali. , 2008, The American journal of tropical medicine and hygiene.
[32] H. Tinto,et al. Chloroquine‐resistance molecular markers (Pfcrt T76 and Pfmdr‐1 Y86) and amodiaquine resistance in Burkina Faso , 2008, Tropical medicine & international health : TM & IH.
[33] P. Rosenthal,et al. Randomized comparison of amodiaquine plus sulfadoxine-pyrimethamine, artemether-lumefantrine, and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Burkina Faso. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[34] Diego F. Echeverry,et al. Short report: polymorphisms in the pfcrt and pfmdr1 genes of Plasmodium falciparum and in vitro susceptibility to amodiaquine and desethylamodiaquine. , 2007, The American journal of tropical medicine and hygiene.
[35] A. Mårtensson,et al. Selection of pfmdr1 mutations after amodiaquine monotherapy and amodiaquine plus artemisinin combination therapy in East Africa. , 2007, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.
[36] S. Krishna,et al. The role of pfmdr1 in Plasmodium falciparum tolerance to artemether‐lumefantrine in Africa , 2007, Tropical medicine & international health : TM & IH.
[37] Georgina S. Humphreys,et al. Amodiaquine and Artemether-Lumefantrine Select Distinct Alleles of the Plasmodium falciparum mdr1 Gene in Tanzanian Children Treated for Uncomplicated Malaria , 2006, Antimicrobial Agents and Chemotherapy.
[38] C. Roper,et al. Artesunate + amodiaquine and artesunate + sulphadoxine–pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine‐resistant haplotypes , 2006, Tropical medicine & international health : TM & IH.
[39] D. Fidock,et al. Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin. , 2006, The Journal of infectious diseases.
[40] D. Wirth,et al. Association between mutations in Plasmodium falciparum chloroquine resistance transporter and P. falciparum multidrug resistance 1 genes and in vivo amodiaquine resistance in P. falciparum malaria-infected children in Nigeria. , 2006, The American journal of tropical medicine and hygiene.
[41] C. Obonyo,et al. Amodiaquine resistant Plasmodium falciparum malaria in vivo is associated with selection of pfcrt 76T and pfmdr1 86Y. , 2006, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.
[42] R. Price,et al. Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria. , 2006, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[43] P. Rosenthal,et al. Selection of Plasmodium falciparum pfmdr1 Alleles following Therapy with Artemether-Lumefantrine in an Area of Uganda where Malaria Is Highly Endemic , 2006, Antimicrobial Agents and Chemotherapy.
[44] Abdullah S. Ali,et al. Efficacy of artesunate plus amodiaquine versus that of artemether-lumefantrine for the treatment of uncomplicated childhood Plasmodium falciparum malaria in Zanzibar, Tanzania. , 2005, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[45] N. Ford,et al. Malaria in the Nuba Mountains of Sudan: baseline genotypic resistance and efficacy of the artesunate plus sulfadoxine-pyrimethamine and artesunate plus amodiaquine combinations. , 2005, Transactions of the Royal Society of Tropical Medicine and Hygiene.
[46] R. Hallett,et al. Amodiaquine alone, amodiaquine+sulfadoxine-pyrimethamine, amodiaquine+artesunate, and artemether-lumefantrine for outpatient treatment of malaria in Tanzanian children: a four-arm randomised effectiveness trial , 2005, The Lancet.
[47] C. Karema,et al. Is amodiaquine failing in Rwanda? Efficacy of amodiaquine alone and combined with artesunate in children with uncomplicated malaria , 2004, Tropical medicine & international health : TM & IH.
[48] François Nosten,et al. Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number , 2004, The Lancet.
[49] A. Nzila,et al. Short report: association between chloroquine and amodiaquine resistance and allelic variation in the Plasmodium falciparum multiple drug resistance 1 gene and the chloroquine resistance transporter gene in isolates from the upper Nile in southern Sudan. , 2003, The American journal of tropical medicine and hygiene.
[50] S. Meshnick,et al. Resistance to Antimalarials in Southeast Asia and Genetic Polymorphisms in pfmdr1 , 2003, Antimicrobial Agents and Chemotherapy.
[51] Jahar B Choudhury,et al. Non‐parametric confidence interval estimation for competing risks analysis: application to contraceptive data , 2002, Statistics in medicine.
[52] D. Warhurst. A molecular marker for chloroquine-resistant falciparum malaria. , 2001, The New England journal of medicine.
[53] M. Duraisingh,et al. The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin. , 2000, Molecular and biochemical parasitology.
[54] N. White,et al. Pharmacokinetics and Pharmacodynamics of Lumefantrine (Benflumetol) in Acute Falciparum Malaria , 2000, Antimicrobial Agents and Chemotherapy.
[55] K. Kirk,et al. Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum , 2000, Nature.
[56] C. Drakeley,et al. Evidence for selection for the tyrosine-86 allele of the pfmdr 1 gene of Plasmodium falciparum by chloroquine and amodiaquine , 1997, Parasitology.
[57] C G Thomas,et al. Pharmacokinetics of artemether after oral administration to healthy Thai males and patients with acute, uncomplicated falciparum malaria. , 1994, British journal of clinical pharmacology.
[58] David A. Schoenfeld,et al. Partial residuals for the proportional hazards regression model , 1982 .
[59] P. Kofoed,et al. Similar efficacy and tolerability of double-dose chloroquine and artemether-lumefantrine for treatment of Plasmodium falciparum infection in Guinea-Bissau: a randomized trial. , 2011, The Journal of infectious diseases.
[60] Organización Mundial de la Salud. Methods and techniques for clinical trials on antimalarial drug efficacy: genotyping to identify parasite populations , 2008 .
[61] R. Price,et al. Intrahost selection of Plasmodium falciparum pfmdr1 alleles after antimalarial treatment on the northwestern border of Thailand. , 2007, The Journal of infectious diseases.