On the mechanics of impact neurotrauma: a review and critical synthesis.

A computational modeling technique for the simulation of head impact mechanics is proposed as a tool for the study of traumatic brain injury (TBI). The capabilities, limitations, and consequently the utilities of this technique are discussed in light of the current computing and imaging technologies and their prospective advancement. A significant portion of the mechanics, relevant to head impact simulation, has been incorporated into this computational technique resulting in automated devices that ease the technical burden of biomechanical analysis of TBI mechanisms. A brief exposition of the concepts utilized in these devices is given and their basis in experiment is discussed.

[1]  A. Holbourn,et al.  Mechanism of head injuries , 1943 .

[2]  A. Ommaya,et al.  Whiplash injury and brain damage: an experimental study. , 1968, JAMA.

[3]  David F. Meaney,et al.  Distribution of Forebrain Diffuse Axonal Injury Following Inertial Closed Head Injury in Miniature Swine , 1994, Experimental Neurology.

[4]  A. Ommaya,et al.  Cerebral concussion and traumatic unconsciousness. Correlation of experimental and clinical observations of blunt head injuries. , 1974, Brain : a journal of neurology.

[5]  A. Holbourn.  MECHANICS OF HEAD INJURIES , 1943 .

[6]  S. Strich,et al.  SHEARING OF NERVE FIBRES AS A CAUSE OF BRAIN DAMAGE DUE TO HEAD INJURY: A Pathological Study of Twenty Cases , 1961 .

[7]  J. Adams,et al.  Diffuse axonal injury and traumatic coma in the primate , 1982, Annals of neurology.

[8]  W. H. Reed,et al.  A semi-implicit method for two-phase fluid dynamics , 1978 .

[9]  D. Oppenheimer,et al.  Microscopic lesions in the brain following head injury. , 1968, Journal of neurology, neurosurgery, and psychiatry.

[10]  J. Currey,et al.  The mechanical consequences of variation in the mineral content of bone. , 1969, Journal of biomechanics.

[11]  A E Hirsch,et al.  Cerebral Concussion in the Monkey: An Experimental Model , 1966, Science.

[12]  Lawrence E. Thibault,et al.  Mechanisms of impact head injury , 1994 .

[13]  F A Bandak,et al.  An imaging-based computational and experimental study of skull fracture: finite element model development. , 1995, Journal of neurotrauma.