A History of Repeated Alcohol Intoxication Promotes Cognitive Impairment and Gene Expression Signatures of Disease Progression in the 3xTg Mouse Model of Alzheimer’s Disease
暂无分享,去创建一个
A. Roberts | F. Giorgi | P. Sanna | D. Mercatelli | T. Kawamura | V. Repunte‐Canonigo | Chiara Cabrelle | Nathan J. O’Connor | Nathan J. O'Connor
[1] Xuezhong Li,et al. The clinical correlation between Alzheimer's disease and epilepsy , 2022, Frontiers in Neurology.
[2] Fei Li,et al. A Diagnostic Model for Alzheimer’s Disease Based on Blood Levels of Autophagy-Related Genes , 2022, Frontiers in Aging Neuroscience.
[3] F. Giorgi,et al. The R Language: An Engine for Bioinformatics and Data Science , 2022, Life.
[4] Viktoriya D. Nikolova,et al. Adolescent Binge Alcohol Enhances Early Alzheimer’s Disease Pathology in Adulthood Through Proinflammatory Neuroimmune Activation , 2022, Frontiers in Pharmacology.
[5] Z. Wang,et al. ATG16L2 inhibits NLRP3 inflammasome activation through promoting ATG5‐12‐16L1 complex assembly and autophagy , 2022, European journal of immunology.
[6] S. Edland,et al. Midlife alcohol consumption and later life cognitive impairment: Light drinking is not protective and APOE genotype does not change this relationship , 2022, PloS one.
[7] K. Lunetta,et al. Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease , 2022, Alzheimer's & dementia : the journal of the Alzheimer's Association.
[8] S. Jakobs,et al. Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors , 2021, eLife.
[9] Evan Z. Macosko,et al. A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex , 2021, Nature.
[10] G. Petrosillo,et al. Exploring the Ability of LARS2 Carboxy-Terminal Domain in Rescuing the MELAS Phenotype , 2021, Life.
[11] Conor D. Cox,et al. Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer’s disease , 2021, Nature Communications.
[12] A. Mortazavi,et al. Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease , 2021, bioRxiv.
[13] L. Mewton,et al. Alcohol use and dementia: new research directions. , 2020, Current opinion in psychiatry.
[14] Araxi O. Urrutia,et al. Transcriptional, Behavioral and Biochemical Profiling in the 3xTg-AD Mouse Model Reveals a Specific Signature of Amyloid Deposition and Functional Decline in Alzheimer’s Disease , 2020, Frontiers in Neuroscience.
[15] Raphael Gottardo,et al. Integrated analysis of multimodal single-cell data , 2020, Cell.
[16] P. Greengard,et al. Innate immunity protein IFITM3 modulates γ-secretase in Alzheimer disease , 2020, Nature.
[17] P. Greengard,et al. The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease , 2020, Nature.
[18] W. Wong. Economic burden of Alzheimer disease and managed care considerations. , 2020, The American journal of managed care.
[19] A. Zarbock,et al. ArhGAP15, a RacGAP, Acts as a Temporal Signaling Regulator of Mac-1 Affinity in Sterile Inflammation , 2020, The Journal of Immunology.
[20] 2020 Alzheimer's disease facts and figures , 2020, Alzheimer's & dementia : the journal of the Alzheimer's Association.
[21] Daniele Mercatelli,et al. corto: a lightweight R package for Gene Network Inference and Master Regulator Analysis , 2020, bioRxiv.
[22] D. Y. Lee,et al. Association of moderate alcohol intake with in vivo amyloid-beta deposition in human brain: A cross-sectional study , 2020, PLoS medicine.
[23] Nicholas E. Propson,et al. Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease. , 2020, The Journal of clinical investigation.
[24] S. Baserga,et al. Ribosomopathies: Old Concepts, New Controversies. , 2019, Trends in genetics : TIG.
[25] Gary D. Bader,et al. Single-cell transcriptomic profiling of the aging mouse brain , 2019, Nature Neuroscience.
[26] J. Williamson,et al. Alcohol Consumption and Risk of Dementia and Cognitive Decline Among Older Adults With or Without Mild Cognitive Impairment , 2019, JAMA network open.
[27] A. Agoglia,et al. Alcohol Drinking Exacerbates Neural and Behavioral Pathology in the 3xTg-AD Mouse Model of Alzheimer’s Disease , 2019, bioRxiv.
[28] S. Newhouse,et al. Transcriptomic analysis of probable asymptomatic and symptomatic alzheimer brains , 2019, Brain, Behavior, and Immunity.
[29] S. Quake,et al. Brain endothelial cells are exquisite sensors of age-related circulatory cues , 2019, bioRxiv.
[30] P. Lewczuk,et al. Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer’s Disease , 2019, Alzheimer's Research & Therapy.
[31] R. Firestein,et al. Molecular and in vivo Functions of the CDK8 and CDK19 Kinase Modules , 2019, Front. Cell Dev. Biol..
[32] J. Rehm,et al. Alcohol use and dementia: a systematic scoping review , 2019, Alzheimer's Research & Therapy.
[33] M. Sortino,et al. Early compensatory responses against neuronal injury: A new therapeutic window of opportunity for Alzheimer's Disease? , 2018, CNS neuroscience & therapeutics.
[34] Helen E. Parkinson,et al. The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019 , 2018, Nucleic Acids Res..
[35] A. Klegeris,et al. Emerging roles of microglial cathepsins in neurodegenerative disease , 2018, Brain Research Bulletin.
[36] Carole Dufouil,et al. Contribution of alcohol use disorders to the burden of dementia in France 2008-13: a nationwide retrospective cohort study. , 2018, The Lancet. Public health.
[37] Quincy M. Samus,et al. Dementia prevention, intervention, and care , 2017, The Lancet.
[38] Jae-Rin Lee,et al. Regulation of inflammatory gene expression in macrophages by epithelial-stromal interaction 1 (Epsti1). , 2017, Biochemical and biophysical research communications.
[39] R. Weinberg,et al. Cadherin-10 Maintains Excitatory/Inhibitory Ratio through Interactions with Synaptic Proteins , 2017, The Journal of Neuroscience.
[40] Shiyong Huang,et al. Developmental Disruption of GABAAR-Meditated Inhibition in Cntnap2 KO Mice , 2017, eNeuro.
[41] P. Gregersen,et al. Increased Cathepsin S in Prdm1−/− dendritic cells alters TFH repertoire and contributes to lupus , 2017, Nature Immunology.
[42] S. Newton,et al. Cognitive dysfunction in major depression and Alzheimer’s disease is associated with hippocampal–prefrontal cortex dysconnectivity , 2017, Neuropsychiatric disease and treatment.
[43] Zhengdong D. Zhang,et al. Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein α , 2017, The Journal of Biological Chemistry.
[44] F. Crews,et al. Microglial-derived miRNA let-7 and HMGB1 contribute to ethanol-induced neurotoxicity via TLR7 , 2017, Journal of Neuroinflammation.
[45] L. Tan,et al. Alcohol consumption and dementia risk: a dose–response meta-analysis of prospective studies , 2017, European Journal of Epidemiology.
[46] Roland Eils,et al. Complex heatmaps reveal patterns and correlations in multidimensional genomic data , 2016, Bioinform..
[47] S. Shultz,et al. Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype , 2016, Acta neuropathologica communications.
[48] D. Kang. Visual perceptual learning for the treatment of visual field defect , 2015 .
[49] V. Vorobyov,et al. The brain compensatory mechanisms and Alzheimer's disease progression: a new protective strategy , 2015, Neural regeneration research.
[50] Takuya Kumazawa,et al. Perturbation of ribosome biogenesis drives cells into senescence through 5S RNP-mediated p53 activation. , 2015, Cell reports.
[51] W. Huber,et al. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.
[52] A W Toga,et al. FASTKD2 is associated with memory and hippocampal structure in older adults , 2014, Molecular Psychiatry.
[53] Rona S. Gertner,et al. Single cell RNA Seq reveals dynamic paracrine control of cellular variation , 2014, Nature.
[54] A. Palmeri,et al. Behavioral assays with mouse models of Alzheimer's disease: practical considerations and guidelines. , 2014, Biochemical pharmacology.
[55] P. Mulholland,et al. Chronic Alcohol Disrupts Dopamine Receptor Activity and the Cognitive Function of the Medial Prefrontal Cortex , 2014, The Journal of Neuroscience.
[56] F. LaFerla,et al. Transgenic mouse models of Alzheimer disease: developing a better model as a tool for therapeutic interventions. , 2012, Current pharmaceutical design.
[57] Mark Ellisman,et al. Cadherin-9 Regulates Synapse-Specific Differentiation in the Developing Hippocampus , 2011, Neuron.
[58] Rajita Sinha,et al. Association of frontal and posterior cortical gray matter volume with time to alcohol relapse: a prospective study. , 2011, The American journal of psychiatry.
[59] P. S. St George-Hyslop,et al. The effect of alcohol and tobacco consumption, and apolipoprotein E genotype, on the age of onset in Alzheimer's disease , 2010, International journal of geriatric psychiatry.
[60] E. Birney,et al. Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt , 2009, Nature Protocols.
[61] A. Owen,et al. AGEMAP: A Gene Expression Database for Aging in Mice , 2007, PLoS genetics.
[62] Anatol C. Kreitzer,et al. Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease , 2007, Neuron.
[63] P. Sanna,et al. Increased expression of protein kinase A inhibitor α (PKI-α) and decreased PKA-regulated genes in chronic intermittent alcohol exposure , 2007, Brain Research.
[64] C. Cotman,et al. Metallothionein-I and -III expression in animal models of Alzheimer disease , 2006, Neuroscience.
[65] M. Ohno,et al. Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation , 2006, The Journal of Neuroscience.
[66] Kevin G Becker,et al. Transcriptional Profiling of Aging in Human Muscle Reveals a Common Aging Signature , 2006, PLoS genetics.
[67] L. Fratiglioni,et al. Role of genes and environments for explaining Alzheimer disease. , 2006, Archives of general psychiatry.
[68] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[69] J. D. McGaugh,et al. Intraneuronal Aβ Causes the Onset of Early Alzheimer’s Disease-Related Cognitive Deficits in Transgenic Mice , 2005, Neuron.
[70] K. Iwamoto,et al. Mitochondrial DNA 3243A>G mutation and increased expression of LARS2 gene in the brains of patients with bipolar disorder and schizophrenia , 2005, Biological Psychiatry.
[71] H. Becker,et al. Increased ethanol drinking after repeated chronic ethanol exposure and withdrawal experience in C57BL/6 mice. , 2004, Alcoholism, clinical and experimental research.
[72] P. Gorelick,et al. Risk Factors for Vascular Dementia and Alzheimer Disease , 2004, Stroke.
[73] K. Coyle,et al. Cognitive impairments in sober alcoholics: performance on selective and divided attention tasks. , 2004, Drug and alcohol dependence.
[74] M. Mattson,et al. Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles Intracellular Aβ and Synaptic Dysfunction , 2003, Neuron.
[75] L. Kuller,et al. Prospective study of alcohol consumption and risk of dementia in older adults. , 2003, JAMA.
[76] H. Stöhr,et al. Cloning and characterization of WDR17, a novel WD repeat-containing gene on chromosome 4q34. , 2002, Biochimica et biophysica acta.
[77] W. Shan,et al. Neural (N‐) cadherin, a synaptic adhesion molecule, is induced in hippocampal mossy fiber axonal sprouts by seizure , 2002, Journal of neuroscience research.
[78] A. Pfefferbaum,et al. Pattern of motor and cognitive deficits in detoxified alcoholic men. , 2000, Alcoholism, clinical and experimental research.
[79] R. Hale,et al. Repeated episodes of ethanol withdrawal potentiate the severity of subsequent withdrawal seizures: an animal model of alcohol withdrawal "kindling". , 1993, Alcoholism, clinical and experimental research.
[80] R. Morris. Developments of a water-maze procedure for studying spatial learning in the rat , 1984, Journal of Neuroscience Methods.
[81] Ventura County,et al. Alzheimer’s Association , 2020, The Grants Register 2021.
[82] J. Delgado-García,et al. Overexpression of Metallothionein-1 Modulates the Phenotype of the Tg2576 Mouse Model of Alzheimer's Disease. , 2016, Journal of Alzheimer's disease : JAD.
[83] Thomas R. Gingeras,et al. STAR: ultrafast universal RNA-seq aligner , 2013, Bioinform..
[84] D. Selkoe. Alzheimer's disease. , 2011, Cold Spring Harbor perspectives in biology.
[85] P. Sanna,et al. Increased expression of protein kinase A inhibitor alpha (PKI-alpha) and decreased PKA-regulated genes in chronic intermittent alcohol exposure. , 2007, Brain Research.
[86] W. Gaebel,et al. Out-patient behaviour therapy in alcoholism: impact of personality disorders and cognitive impairments. , 2001 .