OBJECTIVES
To study the prevalence of Behçet's disease (BD) in a rural area of Western Turkey.
METHODS
This study was conducted in seven villages in the rural Havsa region which has a total population of 5727. The physicians and medical students visited every household and distributed a questionnaire on the symptoms of rheumatic disorders. One of the questions was whether they had ever suffered from mouth ulcers. If the response was affirmative the proband was examined by a rheumatologist and a dermatologist for other symptoms. The individuals with true aphthous ulcerations had pathergy tests and were invited to the hospital for ophtalmic examinations.
RESULTS
Of the 5203 individuals who participated in this survey, 4861 were 10 years or older. 124 out of 190 individuals who responded positively to the question regarding the presence of mouth ulcers had true aphthous ulcerations. 115/124 underwent a pathergy test and 4 showed positive reactions without any other stigmata of BD, except for folliculitis in one. Among the individuals with a negative pathergy test, 2 had acneiform skin lesions and 1 a genital ulcer. No individual exhibited any ocular symptoms or findings characteristic for BD. Only 1 person with aphthous ulceration, folliculitis and a positive pathergy test was considered to have BD.
CONCLUSION
In this survey, the prevalence of BD was found to be 2: 10,000 (95% confidence interval 0 to 4.3: 10,000). This figure is lower than what has been reported in four previous studies from different regions in Turkey. This finding might be due to ethnic distribution and geographical differences.
[1]
A. Gül,et al.
Prevalence of Behçet's disease in Istanbul, Turkey
,
2003,
International journal of dermatology.
[2]
A. Idil,et al.
The prevalence of Behçet’s disease above the age of 10 years The results of a pilot study conducted at the Park Primary Health Care Center in Ankara, Turkey
,
2002,
Ophthalmic epidemiology.
[3]
A. Bakkaloğlu,et al.
Prevalence of juvenile chronic arthritis and familial Mediterranean fever in Turkey: a field study.
,
1998,
The Journal of rheumatology.
[4]
Calvin G. Barnes,et al.
Response to intradermal injection of monosodium urate crystals in Behçet's syndrome.
,
1991,
Annals of the rheumatic diseases.
[5]
International Study Group for Behçet's Disease,et al.
Criteria for diagnosis of Behcet's disease
,
1990,
The Lancet.
[6]
H. Yazıcı,et al.
The prevalence of Behçet's syndrome in a rural area in northern Turkey.
,
1988,
The Journal of rheumatology.
[7]
M. Chamberlain.
Behcet's syndrome in 32 patients in Yorkshire.
,
1977,
Annals of the rheumatic diseases.