An Implantable Ionic Wireless Power Transfer System Facilitating Electrosynthesis.

A number of implantable biomedical devices have been developed and wireless power transfer (WPT) systems are emerging as a way to provide power to these devices without requiring a hardwired connection. Most of WPT have been based on conventional conductive materials, such as metals, which tend to be less biocompatible and stiff. Herein, we describe a development of an ionic wireless power transfer (IWPT) system using hydrogel receivers that are soft and biocompatible. Although the hydrogel receiver has lower conductivity than metal (ρgel/ρmetal ~10-7), a capacitive coupling between receiver and transmitter enables for IWPT to deliver 4 mA of current at its resonance frequency. The capacitive coupling through the dielectric and the electrolyte was analyzed including parasitic effect, and the IWPT was applied to implantable devices to transfer power via the skin. The IWPT system was further developed to facilitate electrosynthesis. Generation of nicotinamide adenine dinucleotide phosphate (NADPH), reducing agent in metabolism, was demonstrated by IWPT to show its potential for electrosynthesis.

[1]  Jeong-Yun Sun,et al.  Stretchable Ionics – A Promising Candidate for Upcoming Wearable Devices , 2018, Advanced materials.

[2]  Hung Cao,et al.  Power Approaches for Implantable Medical Devices , 2015, Sensors.

[3]  Choon Chiang Foo,et al.  Stretchable, Transparent, Ionic Conductors , 2013, Science.

[4]  Zhong Lin Wang,et al.  Piezoelectric Nanogenerators Based on Zinc Oxide Nanowire Arrays , 2006, Science.

[5]  Jonathan A. Fan,et al.  Stretchable batteries with self-similar serpentine interconnects and integrated wireless recharging systems , 2013, Nature Communications.

[6]  Shane K. Mitchell,et al.  Hydraulically amplified self-healing electrostatic actuators with muscle-like performance , 2018, Science.

[7]  G Antonioli,et al.  [Implantable cardiac stimulator with a new solid-state lithium battery]. , 1973, Minerva medica.

[8]  Z. Suo,et al.  Hydrogel ionotronics , 2018, Nature Reviews Materials.

[9]  Chris Mi,et al.  A Review on the Recent Development of Capacitive Wireless Power Transfer Technology , 2017 .

[10]  Sanlin S. Robinson,et al.  Highly stretchable electroluminescent skin for optical signaling and tactile sensing , 2016, Science.

[11]  Michael D. Paskett,et al.  Wireless bioresorbable electronic system enables sustained nonpharmacological neuroregenerative therapy , 2018, Nature Medicine.

[12]  A. Babakhani,et al.  Stretchable transparent wireless charging coil fabricated by negative transfer printing. , 2019, ACS applied materials & interfaces.

[13]  Nitish V. Thakor,et al.  Wireless Power Transfer Strategies for Implantable Bioelectronics , 2017, IEEE Reviews in Biomedical Engineering.

[14]  Reid R. Harrison,et al.  Designing Efficient Inductive Power Links for Implantable Devices , 2007, 2007 IEEE International Symposium on Circuits and Systems.

[15]  Roland Zengerle,et al.  Energy harvesting by implantable abiotically catalyzed glucose fuel cells , 2008 .

[16]  Nitish V. Thakor,et al.  Wireless Power Delivery to Flexible Subcutaneous Implants Using Capacitive Coupling , 2017, IEEE Transactions on Microwave Theory and Techniques.

[17]  Zhigang Suo,et al.  Ionic skin , 2014, Advanced materials.

[18]  Zhong Lin Wang,et al.  Self-powered nanowire devices. , 2010, Nature nanotechnology.

[19]  W.J. Heetderks,et al.  RF powering of millimeter- and submillimeter-sized neural prosthetic implants , 1988, IEEE Transactions on Biomedical Engineering.

[20]  Hyung-Jun Koo,et al.  Ionic current devices-Recent progress in the merging of electronic, microfluidic, and biomimetic structures. , 2013, Biomicrofluidics.

[21]  Jeong-Yun Sun,et al.  Highly stretchable, transparent ionic touch panel , 2016, Science.

[22]  Shahriar Mirabbasi,et al.  Bend, stretch, and touch: Locating a finger on an actively deformed transparent sensor array , 2017, Science Advances.

[23]  S. Omanovic,et al.  Direct electrochemical regeneration of the cofactor NADH on bare Ti, Ni, Co and Cd electrodes: The influence of electrode potential and electrode material , 2014 .

[24]  Zhenan Bao,et al.  Biodegradable and flexible arterial-pulse sensor for the wireless monitoring of blood flow , 2019, Nature Biomedical Engineering.

[25]  Dukhyun Choi,et al.  Transparent and attachable ionic communicators based on self-cleanable triboelectric nanogenerators , 2018, Nature Communications.

[26]  Minkyu Je,et al.  High-Efficiency Wireless Power Transfer for Biomedical Implants by Optimal Resonant Load Transformation , 2013, IEEE Transactions on Circuits and Systems I: Regular Papers.