Quantitative proteomics and phosphoproteomics reveal novel insights into complexity and dynamics of the EGFR signaling network
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S. Skvortsov | L. Huber | Sandra Morandell | T. Stasyk | Stefan Ascher | Sandra Morandell | Lukas A Huber | Stefan Ascher | Taras Stasyk | Sergej Skvortsov | Lukas A. Huber
[1] P. De Camilli,et al. Epidermal growth factor pathway substrate 15, Eps15. , 1999, The international journal of biochemistry & cell biology.
[2] Roy S Herbst,et al. Review of epidermal growth factor receptor biology. , 2004, International journal of radiation oncology, biology, physics.
[3] Robert Hoffmann,et al. HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms , 2005, BMC Bioinformatics.
[4] D. Stern,et al. Specificity within the EGF family/ErbB receptor family signaling network , 1998, BioEssays : news and reviews in molecular, cellular and developmental biology.
[5] Monilola A. Olayioye,et al. The ErbB signaling network: receptor heterodimerization in development and cancer , 2000, The EMBO journal.
[6] Jens M. Rick,et al. Quantitative mass spectrometry in proteomics: a critical review , 2007, Analytical and bioanalytical chemistry.
[7] J. Downward,et al. Mechanism of Epidermal Growth Factor Regulation of Vav2, a Guanine Nucleotide Exchange Factor for Rac* , 2003, The Journal of Biological Chemistry.
[8] G. Carpenter,et al. Tyrosine phosphorylation of ras GTPase-activating protein does not require association with the epidermal growth factor receptor. , 1993, The Journal of biological chemistry.
[9] H. Kitano,et al. A comprehensive pathway map of epidermal growth factor receptor signaling , 2005, Molecular systems biology.
[10] Monilola A. Olayioye,et al. ErbB-1 and ErbB-2 Acquire Distinct Signaling Properties Dependent upon Their Dimerization Partner , 1998, Molecular and Cellular Biology.
[11] R. Singal,et al. EGFR targeting of solid tumors. , 2007, Cancer control : journal of the Moffitt Cancer Center.
[12] M. Mann,et al. Phosphotyrosine interactome of the ErbB-receptor kinase family , 2005, Molecular systems biology.
[13] M. Kirschner,et al. Stable isotope-free relative and absolute quantitation of protein phosphorylation stoichiometry by MS. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[14] A Ciechanover,et al. Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1. , 1999, Molecular cell.
[15] B. Druker,et al. Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells , 2007, Proteomics.
[16] J. Schlessinger,et al. Cell Signaling by Receptor Tyrosine Kinases , 2000, Cell.
[17] B. Chait,et al. Analysis of phosphorylated proteins and peptides by mass spectrometry. , 2001, Current opinion in chemical biology.
[18] D. Lauffenburger,et al. Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks , 2007, Proceedings of the National Academy of Sciences.
[19] A. Tsygankov,et al. The Cbl family proteins: Ring leaders in regulation of cell signaling , 2006, Journal of cellular physiology.
[20] J Godovac-Zimmermann,et al. Phosphotyrosine 1173 Mediates Binding of the Protein-tyrosine Phosphatase SHP-1 to the Epidermal Growth Factor Receptor and Attenuation of Receptor Signaling* , 1998, The Journal of Biological Chemistry.
[21] P. Sternberg,et al. Positive and negative tissue-specific signaling by a nematode epidermal growth factor receptor. , 1997, Molecular biology of the cell.
[22] D. Fenyo,et al. Phosphotyrosine Signaling Networks in Epidermal Growth Factor Receptor Overexpressing Squamous Carcinoma Cells*S , 2005, Molecular & Cellular Proteomics.
[23] Richard S. Johnson,et al. Studies of ligand-induced site-specific phosphorylation of epidermal growth factor receptor , 2003, Journal of the American Society for Mass Spectrometry.
[24] S. Gygi,et al. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags , 1999, Nature Biotechnology.
[25] Kristie L. Rose,et al. Analysis of proteins and peptides on a chromatographic timescale by electron‐transfer dissociation MS , 2007, The FEBS journal.
[26] M. Waterfield,et al. Identification of a novel autophosphorylation site (P4) on the epidermal growth factor receptor. , 1989, The Biochemical journal.
[27] Gavin MacBeath,et al. A quantitative protein interaction network for the ErbB receptors using protein microarrays , 2006, Nature.
[28] Monilola A. Olayioye,et al. The ErbB receptor tyrosine family as signal integrators. , 2001, Endocrine-related cancer.
[29] A. Kazlauskas,et al. c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF. , 1999, Genes & development.
[30] J. Cooper,et al. Control of actin assembly and disassembly at filament ends. , 2000, Current opinion in cell biology.
[31] D. Kassel,et al. In vitro phosphorylation of the epidermal growth factor receptor autophosphorylation domain by c-src: identification of phosphorylation sites and c-src SH2 domain binding sites. , 1995, Biochemistry.
[32] E. Petricoin,et al. Dynamic Profiling of the Post-translational Modifications and Interaction Partners of Epidermal Growth Factor Receptor Signaling after Stimulation by Epidermal Growth Factor Using Extended Range Proteomic Analysis (ERPA)*S , 2006, Molecular & Cellular Proteomics.
[33] Eoin Fahy,et al. Identification of protein associations in organelles, using mass spectrometry-based proteomics. , 2004, Mass spectrometry reviews.
[34] Lukas N. Mueller,et al. SuperHirn – a novel tool for high resolution LC‐MS‐based peptide/protein profiling , 2007, Proteomics.
[35] Etienne Gagnon,et al. Organelle proteomics: looking at less to see more. , 2003, Trends in cell biology.
[36] C. Huck,et al. Quantitative detection of phosphoproteins by combination of two‐dimensional difference gel electrophoresis and phosphospecific fluorescent staining , 2005, Electrophoresis.
[37] Joseph Schlessinger,et al. A Novel Positive Feedback Loop Mediated by the Docking Protein Gab1 and Phosphatidylinositol 3-Kinase in Epidermal Growth Factor Receptor Signaling , 2000, Molecular and Cellular Biology.
[38] Blagoy Blagoev,et al. Quantitative proteomic assessment of very early cellular signaling events , 2007, Nature Biotechnology.
[39] J. Yates,et al. Proteomics of organelles and large cellular structures , 2005, Nature Reviews Molecular Cell Biology.
[40] M. Fussenegger,et al. Use of antibodies for detection of phosphorylated proteins separated by two‐dimensional gel electrophoresis , 2001, Proteomics.
[41] Steven W. Taylor,et al. Global organellar proteomics. , 2003, Trends in biotechnology.
[42] E. Bradbury,et al. Site-specific mass tagging with stable isotopes in proteins for accurate and efficient protein identification. , 2000, Analytical chemistry.
[43] D. Lauffenburger,et al. Time-resolved Mass Spectrometry of Tyrosine Phosphorylation Sites in the Epidermal Growth Factor Receptor Signaling Network Reveals Dynamic Modules*S , 2005, Molecular & Cellular Proteomics.
[44] S. Parsons,et al. c-Src and cooperating partners in human cancer. , 2004, Cancer cell.
[45] G. Tortora,et al. Rational bases for the development of EGFR inhibitors for cancer treatment. , 2007, The international journal of biochemistry & cell biology.
[46] D. Lauffenburger,et al. Computational modeling of the EGF-receptor system: a paradigm for systems biology. , 2003, Trends in cell biology.
[47] R. Aebersold,et al. Mass spectrometry-based proteomics , 2003, Nature.
[48] M. Matsuda,et al. R-Ras regulates exocytosis by Rgl2/Rlf-mediated activation of RalA on endosomes. , 2007, Molecular biology of the cell.
[49] A. Ullrich,et al. All autophosphorylation sites of epidermal growth factor (EGF) receptor and HER2/neu are located in their carboxyl-terminal tails. Identification of a novel site in EGF receptor. , 1989, The Journal of biological chemistry.
[50] Albert Sickmann,et al. State‐of‐the‐art in phosphoproteomics , 2005, Proteomics.
[51] M. Mann,et al. Analysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[52] Gary D Bader,et al. Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry , 2002, Nature.
[53] Hanno Steen,et al. Tyrosine Phosphorylation Mapping of the Epidermal Growth Factor Receptor Signaling Pathway* , 2002, The Journal of Biological Chemistry.
[54] Y. Kido,et al. Tyrosines 1148 and 1173 of activated human epidermal growth factor receptors are binding sites of Shc in intact cells. , 1994, The Journal of biological chemistry.
[55] Andrew H. Thompson,et al. Tandem mass tags: a novel quantification strategy for comparative analysis of complex protein mixtures by MS/MS. , 2003, Analytical chemistry.
[56] W. Kolch,et al. Proteomic analysis of phosphorylation, oxidation and nitrosylation in signal transduction. , 2006, Biochimica et biophysica acta.
[57] Weidong Wu,et al. Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor on Tyrosine 845 Is Required for Zinc-induced Ras Activation* , 2002, The Journal of Biological Chemistry.
[58] M. Moran,et al. Distinct tyrosine autophosphorylation sites negatively and positively modulate neu-mediated transformation , 1997, Molecular and cellular biology.
[59] Mark J. Bowser,et al. EGFR-induced cell migration is mediated predominantly by the JAK-STAT pathway in primary esophageal keratinocytes. , 2004, American journal of physiology. Gastrointestinal and liver physiology.
[60] M. Mann,et al. Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks , 2006, Cell.
[61] W. Hong,et al. Endofin, an Endosomal FYVE Domain Protein* , 2001, The Journal of Biological Chemistry.
[62] A. Martin,et al. Assessment of epidermal growth factor receptor (EGFR, ErbB1) and HER2 (ErbB2) protein expression levels and response to lapatinib (Tykerb®, GW572016) in an expanded panel of human normal and tumour cell lines , 2007, Cell proliferation.
[63] Jonathan M Irish,et al. Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications. , 2004, Clinical immunology.
[64] Tony Hunter,et al. Epidermal Growth Factor-Induced Tumor Cell Invasion and Metastasis Initiated by Dephosphorylation and Downregulation of Focal Adhesion Kinase , 2001, Molecular and Cellular Biology.
[65] D. Arnott,et al. Mass Spectrometric Contributions to the Practice of Phosphorylation Site Mapping through 2003 , 2005, Molecular & Cellular Proteomics.
[66] J. Shabanowitz,et al. A neutral loss activation method for improved phosphopeptide sequence analysis by quadrupole ion trap mass spectrometry. , 2004, Analytical chemistry.
[67] T. Hunter,et al. A431 cell variants lacking the blood group A antigen display increased high affinity epidermal growth factor-receptor number, protein-tyrosine kinase activity, and receptor turnover , 1988, The Journal of cell biology.
[68] O. Jensen. Interpreting the protein language using proteomics , 2006, Nature Reviews Molecular Cell Biology.
[69] Masao Nagasaki,et al. Modeling and estimation of dynamic EGFR pathway by data assimilation approach using time series proteomic data. , 2006, Genome informatics. International Conference on Genome Informatics.
[70] L. Huber,et al. Subcellular fractionation, electromigration analysis and mapping of organelles. , 1999, Journal of chromatography. B, Biomedical sciences and applications.
[71] L. Huber,et al. Organelle proteomics: implications for subcellular fractionation in proteomics. , 2003, Circulation research.
[72] N. Lydon,et al. Src Phosphorylation of the Epidermal Growth Factor Receptor at Novel Sites Mediates Receptor Interaction with Src and P85α (*) , 1995, The Journal of Biological Chemistry.
[73] N. Normanno,et al. Epidermal growth factor-related peptides and their receptors in human malignancies. , 1995, Critical reviews in oncology/hematology.
[74] S. Skvortsov,et al. Identification of Endosomal Epidermal Growth Factor Receptor Signaling Targets by Functional Organelle Proteomics *S , 2007, Molecular & Cellular Proteomics.
[75] Lukas N. Mueller,et al. An assessment of software solutions for the analysis of mass spectrometry based quantitative proteomics data. , 2008, Journal of proteome research.
[76] M. Yaffe. Phosphotyrosine-binding domains in signal transduction , 2002, Nature Reviews Molecular Cell Biology.
[77] Joseph Schlessinger,et al. SH2 and PTB Domains in Tyrosine Kinase Signaling , 2003, Science's STKE.
[78] J. Borlak,et al. Quantitative mass spectrometry to investigate epidermal growth factor receptor phosphorylation dynamics. , 2008, Mass spectrometry reviews.
[79] A. Pandey,et al. Detection of tyrosine phosphorylated peptides by precursor ion scanning quadrupole TOF mass spectrometry in positive ion mode. , 2001, Analytical chemistry.
[80] Hanno Steen,et al. Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome. , 2002, Trends in biotechnology.
[81] C. Ward,et al. Systematic Mapping of Potential Binding Sites for Shc and Grb2 SH2 Domains on Insulin Receptor Substrate-1 and the Receptors for Insulin, Epidermal Growth Factor, Platelet-derived Growth Factor, and Fibroblast Growth Factor (*) , 1996, The Journal of Biological Chemistry.
[82] Giulio Superti-Furga,et al. A physical and functional map of the human TNF-α/NF-κB signal transduction pathway , 2004, Nature Cell Biology.
[83] M. Mann,et al. PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites , 2007, Genome Biology.
[84] S. Parsons,et al. STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor* , 2003, The Journal of Biological Chemistry.
[85] William S Hancock,et al. Extended Range Proteomic Analysis (ERPA): a new and sensitive LC-MS platform for high sequence coverage of complex proteins with extensive post-translational modifications-comprehensive analysis of beta-casein and epidermal growth factor receptor (EGFR). , 2005, Journal of proteome research.
[86] James R. Knight,et al. A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae , 2000, Nature.
[87] H. Cooper,et al. Liquid Chromatography Electron Capture Dissociation Tandem Mass Spectrometry (LC-ECD-MS/MS) versus Liquid Chromatography Collision-induced Dissociation Tandem Mass Spectrometry (LC-CID-MS/MS) for the Identification of Proteins , 2007, Journal of the American Society for Mass Spectrometry.
[88] K. Parker,et al. Multiplexed Protein Quantitation in Saccharomyces cerevisiae Using Amine-reactive Isobaric Tagging Reagents*S , 2004, Molecular & Cellular Proteomics.
[89] R. Davis,et al. Mechanism of phosphorylation of the epidermal growth factor receptor at threonine 669. , 1989, The Journal of biological chemistry.
[90] R. Epstein,et al. Phosphoproteomic fingerprinting of epidermal growth factor signaling and anticancer drug action in human tumor cells. , 2003, Molecular cancer therapeutics.
[91] C. Damsky,et al. FAK integrates growth-factor and integrin signals to promote cell migration , 2000, Nature Cell Biology.
[92] E. Gilles,et al. Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors , 2002, Nature Biotechnology.
[93] Y. Yarden,et al. Untangling the ErbB signalling network , 2001, Nature Reviews Molecular Cell Biology.
[94] R. Ozawa,et al. A comprehensive two-hybrid analysis to explore the yeast protein interactome , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[95] Tony Pawson,et al. Specificity in Signal Transduction From Phosphotyrosine-SH2 Domain Interactions to Complex Cellular Systems , 2004, Cell.
[96] Karl Mechtler,et al. Phosphoproteomics strategies for the functional analysis of signal transduction , 2006, Proteomics.
[97] John Mendelsohn,et al. The EGF receptor family as targets for cancer therapy , 2000, Oncogene.
[98] David J Riese,et al. Mutational activation of ErbB family receptor tyrosine kinases: insights into mechanisms of signal transduction and tumorigenesis , 2007, BioEssays : news and reviews in molecular, cellular and developmental biology.
[99] Steven P Gygi,et al. Signaling networks assembled by oncogenic EGFR and c-Met , 2008, Proceedings of the National Academy of Sciences.
[100] M. Sliwkowski,et al. Binding specificities and affinities of egf domains for ErbB receptors , 1999, FEBS letters.
[101] Douglas A Lauffenburger,et al. Modeling and computational analysis of EGF receptor-mediated cell communication in Drosophila oogenesis. , 2002, Development.
[102] G. Carpenter,et al. The Role of Individual SH2 Domains in Mediating Association of Phospholipase C-γ1 with the Activated EGF Receptor* , 1999, The Journal of Biological Chemistry.
[103] B. Kholodenko,et al. Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor* , 1999, The Journal of Biological Chemistry.
[104] T. Ito,et al. Toward a protein-protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all possible combinations between the yeast proteins. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[105] J. Boonstra,et al. Three classes of epidermal growth factor receptors on HeLa cells. , 1991, The Journal of biological chemistry.
[106] Sampsa Hautaniemi,et al. Effects of HER2 overexpression on cell signaling networks governing proliferation and migration , 2006, Molecular systems biology.
[107] T. Kwok,et al. Differences in EGF related radiosensitisation of human squamous carcinoma cells with high and low numbers of EGF receptors. , 1991, British Journal of Cancer.
[108] M. Mann,et al. Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics , 2004, Nature Biotechnology.
[109] Y. Zhang,et al. IntAct—open source resource for molecular interaction data , 2006, Nucleic Acids Res..
[110] I. Dikic,et al. Compartmentalization of growth factor receptor signalling. , 2005, Current opinion in cell biology.
[111] Blagoy Blagoev,et al. A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling , 2003, Nature Biotechnology.
[112] Albert Sickmann,et al. Challenges in mass spectrometry‐based proteomics , 2004, Proteomics.
[113] Y. Kido,et al. Shc phosphotyrosine-binding domain dominantly interacts with epidermal growth factor receptors and mediates Ras activation in intact cells. , 1998, Molecular endocrinology.
[114] L. Alberghina,et al. Kinetics and regulation of the tyrosine phosphorylation of epidermal growth factor receptor in intact A431 cells , 1988, Molecular and cellular biology.
[115] Tony Pawson,et al. NetworKIN: a resource for exploring cellular phosphorylation networks , 2007, Nucleic Acids Res..
[116] Brian A. Hemmings,et al. Protein kinase B/Akt at a glance , 2005, Journal of Cell Science.
[117] K. Helin,et al. Internalization and down-regulation of the human epidermal growth factor receptor are regulated by the carboxyl-terminal tyrosines. , 1991, The Journal of biological chemistry.
[118] W. Kolch. Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. , 2000, The Biochemical journal.
[119] H. Dohlman,et al. MAPK kinase kinases (MKKKs) as a target class for small-molecule inhibition to modulate signaling networks and gene expression. , 2005, Current opinion in chemical biology.
[120] J. Downward,et al. Autophosphorylation sites on the epidermal growth factor receptor , 1984, Nature.
[121] U. Hellman,et al. Phosphoproteome profiling of transforming growth factor (TGF)-beta signaling: abrogation of TGFbeta1-dependent phosphorylation of transcription factor-II-I (TFII-I) enhances cooperation of TFII-I and Smad3 in transcription. , 2005, Molecular biology of the cell.
[122] P. Bork,et al. Proteome survey reveals modularity of the yeast cell machinery , 2006, Nature.
[123] H. Steen,et al. Quadrupole time-of-flight versus triple-quadrupole mass spectrometry for the determination of phosphopeptides by precursor ion scanning. , 2001, Journal of mass spectrometry : JMS.
[124] A. Citri,et al. EGF–ERBB signalling: towards the systems level , 2006, Nature Reviews Molecular Cell Biology.
[125] Waltraud X. Schulze,et al. A Novel Proteomic Screen for Peptide-Protein Interactions* , 2004, Journal of Biological Chemistry.
[126] A. Ullrich,et al. SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high‐affinity binding site for SH2 domains of phospholipase C gamma. , 1992, The EMBO journal.
[127] F. White,et al. Proteomic analysis of cellular signaling , 2004, Expert review of proteomics.
[128] M. Mann,et al. Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics* , 2002, Molecular & Cellular Proteomics.
[129] Kohjiro Ueki,et al. Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone , 1997, Nature.
[130] P. Bork,et al. Functional organization of the yeast proteome by systematic analysis of protein complexes , 2002, Nature.
[131] J. Furuhjelm,et al. The C-terminal end of R-Ras contains a focal adhesion targeting signal , 2003, Journal of Cell Science.
[132] Rebecca B. Riggins,et al. Synergistic Promotion of c-Src Activation and Cell Migration by Cas and AND-34/BCAR3* , 2003, Journal of Biological Chemistry.
[133] S. Gygi,et al. Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[134] J. Bunkenborg,et al. Quantitation of multisite EGF receptor phosphorylation using mass spectrometry and a novel normalization approach. , 2007, Journal of proteome research.
[135] M. Mann,et al. Mass spectrometry–based proteomics turns quantitative , 2005, Nature chemical biology.
[136] M. Dreger. Proteome analysis at the level of subcellular structures. , 2003, European journal of biochemistry.
[137] T. Hunter,et al. The Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and disease. , 1998, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[138] T. Pawson,et al. Assembly of Cell Regulatory Systems Through Protein Interaction Domains , 2003, Science.
[139] C. Tacchetti,et al. Integrin-induced Epidermal Growth Factor (EGF) Receptor Activation Requires c-Src and p130Cas and Leads to Phosphorylation of Specific EGF Receptor Tyrosines* , 2002, The Journal of Biological Chemistry.
[140] L. Silengo,et al. Systematic Analysis of the Epidermal Growth Factor Receptor by Mass Spectrometry Reveals Stimulation-dependent Multisite Phosphorylation*S , 2005, Molecular & Cellular Proteomics.
[141] Huang Shao,et al. Identification and characterization of signal transducer and activator of transcription 3 recruitment sites within the epidermal growth factor receptor. , 2003, Cancer research.
[142] G. M. Walton,et al. Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosphorylation of cell substrates. , 1990, The Journal of biological chemistry.
[143] Blagoy Blagoev,et al. Mechanism of Divergent Growth Factor Effects in Mesenchymal Stem Cell Differentiation , 2005, Science.
[144] J. Schlessinger,et al. Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor , 1994, Molecular and cellular biology.
[145] S. Cole,et al. Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions. , 2005, Journal of molecular biology.
[146] L. Huber,et al. Zooming in: Fractionation strategies in proteomics , 2004, Proteomics.
[147] S. Snyder,et al. Phospholipase C-γ: diverse roles in receptor-mediated calcium signaling , 2005 .
[148] Y. Kido,et al. Grb2/Ash binds directly to tyrosines 1068 and 1086 and indirectly to tyrosine 1148 of activated human epidermal growth factor receptors in intact cells. , 1994, The Journal of biological chemistry.