Association of BDNF Polymorphisms with the Risk of Epilepsy: a Multicenter Study

[1]  D. Zafeiriou,et al.  Association of brain-derived neurotrophic factor (BDNF) and elongator protein complex 4 (ELP4) polymorphisms with benign epilepsy with centrotemporal spikes in a Greek population , 2014, Epilepsy Research.

[2]  C. P. Morris,et al.  BDNF SNPs are implicated in comorbid alcohol dependence in schizophrenia but not in alcohol-dependent patients without schizophrenia. , 2014, Alcohol and alcoholism.

[3]  Tzu-Yun Wang,et al.  Genetic variants of the BDNF and DRD3 genes in bipolar disorder comorbid with anxiety disorder. , 2013, Journal of affective disorders.

[4]  B. Haerian BDNF rs6265 polymorphism and drug addiction: a systematic review and meta-analysis. , 2013, Pharmacogenomics.

[5]  T. Kosten,et al.  Association of BDNF gene polymorphisms with schizophrenia and clinical symptoms in a Chinese population , 2013, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[6]  S. Moshé,et al.  ILAE/IBE/WHO Global Campaign Against Epilepsy: a partnership that works. , 2013, Current opinion in neurology.

[7]  R. Sagar,et al.  Val66Met polymorphism and BDNF levels in Alzheimer's disease patients in North Indian population , 2013, The International journal of neuroscience.

[8]  R. Huganir,et al.  Role of pro-brain-derived neurotrophic factor (proBDNF) to mature BDNF conversion in activity-dependent competition at developing neuromuscular synapses , 2012, Proceedings of the National Academy of Sciences.

[9]  G. Ichim,et al.  Neurotrophins and cell death. , 2012, Experimental cell research.

[10]  J. Huang,et al.  Association of BDNF Gene Polymorphism with Bipolar Disorders in Han Chinese Population , 2012, Genes, brain, and behavior.

[11]  J. Gorski,et al.  Sustained expression of brain-derived neurotrophic factor is required for maintenance of dendritic spines and normal behavior , 2012, Neuroscience.

[12]  J. Welagen,et al.  Role of Neurotrophins in the Development and Function of Neural Circuits That Regulate Energy Homeostasis , 2012, Journal of Molecular Neuroscience.

[13]  E. Bora,et al.  Lack of Association of Childhood Partial Epilepsy with Brain Derived Neurotrophic Factor Gene , 2012, TheScientificWorldJournal.

[14]  Pak Chung Sham,et al.  Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese. , 2012, Human molecular genetics.

[15]  L. Martorell,et al.  Predisposition to epilepsy in fragile X syndrome: Does the Val66Met polymorphism in the BDNF gene play a role? , 2011, Epilepsy & Behavior.

[16]  P. Holmes,et al.  An Overview of Brain-Derived Neurotrophic Factor and Implications for Excitotoxic Vulnerability in the Hippocampus , 2011, International journal of peptides.

[17]  E. Castrén,et al.  Increase in BDNF-mediated TrkB signaling promotes epileptogenesis in a mouse model of mesial temporal lobe epilepsy , 2011, Neurobiology of Disease.

[18]  J. H. Cross,et al.  Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005–2009 , 2010, Epilepsia.

[19]  J. Bragatti,et al.  No major clinical impact of Val66Met BDNF gene polymorphism on temporal lobe epilepsy , 2010, Epilepsy Research.

[20]  B. Lu,et al.  New Insights in the Biology of BDNF Synthesis and Release: Implications in CNS Function , 2009, The Journal of Neuroscience.

[21]  J. McNamara,et al.  Reduction of TrkB expression de novo in the adult mouse impairs epileptogenesis in the kindling model , 2009, Hippocampus.

[22]  Z. Janka,et al.  Association Between BDNF Val66Met Polymorphism and Alzheimer Disease, Dementia With Lewy Bodies, and Pick Disease , 2009, Alzheimer disease and associated disorders.

[23]  Pardis C Sabeti,et al.  Population genetic study of the brain-derived neurotrophic factor (BDNF) gene , 2009, Molecular Psychiatry.

[24]  B. Lu,et al.  Control of extracellular cleavage of ProBDNF by high frequency neuronal activity , 2009, Proceedings of the National Academy of Sciences.

[25]  Chang Yoon Kim,et al.  Brain-Derived Neurotrophic Factor Val/Met Polymorphism and Bipolar Disorder , 2008, Neuropsychobiology.

[26]  Zhijun Zhang,et al.  Association study of the decreased serum BDNF concentrations in amnestic mild cognitive impairment and the Val66Met polymorphism in Chinese Han. , 2008, The Journal of clinical psychiatry.

[27]  Tamara Aid,et al.  Dissecting the human BDNF locus: Bidirectional transcription, complex splicing, and multiple promoters☆ , 2007, Genomics.

[28]  Zhenxin Zhang,et al.  Lack of Association between the BDNF Gene Val66Met Polymorphism and Alzheimer Disease in a Chinese Han Population , 2007, Neuropsychobiology.

[29]  Kaia Palm,et al.  Mouse and rat BDNF gene structure and expression revisited , 2006, Journal of neuroscience research.

[30]  C. Siao,et al.  Genetic Variant BDNF (Val66Met) Polymorphism Alters Anxiety-Related Behavior , 2006, Science.

[31]  S. Tonegawa,et al.  Transgenic brain-derived neurotrophic factor expression causes both anxiogenic and antidepressant effects , 2006, Proceedings of the National Academy of Sciences.

[32]  Pardis C Sabeti,et al.  Positive Natural Selection in the Human Lineage , 2006, Science.

[33]  M. Sperling,et al.  Lack of association between variations in the brain-derived neurotrophic factor (BDNF) gene and temporal lobe epilepsy , 2005, Epilepsy Research.

[34]  H. Scharfman Brain-derived Neurotrophic Factor and Epilepsy—A Missing Link? , 2005, Epilepsy currents.

[35]  C. Crombie,et al.  BDNF gene is a risk factor for schizophrenia in a Scottish population , 2005, Molecular Psychiatry.

[36]  S. Christian,et al.  Linkage disequilibrium of the brain-derived neurotrophic factor Val66Met polymorphism in children with a prepubertal and early adolescent bipolar disorder phenotype. , 2004, The American journal of psychiatry.

[37]  Laurent Givalois,et al.  Physiology of BDNF: focus on hypothalamic function , 2004, Frontiers in Neuroendocrinology.

[38]  F. Tsai,et al.  Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in febrile seizures , 2004, Epilepsy Research.

[39]  M. Karayiorgou,et al.  Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder. , 2003, American journal of human genetics.

[40]  R. Kaji,et al.  Association of partial epilepsy with brain-derived neurotrophic factor (BDNF) gene polymorphisms , 2003, Epilepsy Research.

[41]  M. Egan,et al.  The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function , 2003, Cell.

[42]  Fengzhu Sun,et al.  Haplotype block structure and its applications to association studies: power and study designs. , 2002, American journal of human genetics.

[43]  H. Scharfman,et al.  Review: Epilepsy as an Example of Neural Plasticity , 2002, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

[44]  E. Castrén,et al.  Decreased BDNF signalling in transgenic mice reduces epileptogenesis , 2002, The European journal of neuroscience.

[45]  D. Lo,et al.  Brain-Derived Neurotrophic Factor Differentially Regulates Excitatory and Inhibitory Synaptic Transmission in Hippocampal Cultures , 2000, The Journal of Neuroscience.

[46]  T. Wong,et al.  Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations , 2012, International Journal of Obesity.

[47]  B. Borroni,et al.  The brain-derived neurotrophic factor Val66Met polymorphism is associated with reduced hippocampus perfusion in frontotemporal lobar degeneration. , 2012, Journal of Alzheimer's disease : JAD.

[48]  M. Gratacós,et al.  Met66 in the brain-derived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type , 2003, Molecular Psychiatry.