FINE: improving time and precision of segmentation techniques for vertebral compression fractures in MRI

Lower back pain is often related to spinal diseases. In particular, Vertebral Compression Fractures (VCFs) can impair mobility and compromise quality of life. In a Computer-Aided Diagnosis (CAD) context, the segmentation of VCFs is a challenging task due to non-homogeneous intensities within the same vertebral body. Semiautomatic segmentation methods have been employed to cope with this challenge. However, these methods require inside and outside annotation, which is not practical when analyzing a more significant number of exams. Aimed at minimizing the time spent on manual annotation, we proposed Fast INside Estimation (FINE), which automatically estimates the inside seeds based on the outside seeds. The experimental results with a representative dataset showed that FINE does not demand manual inside annotation, what the competitors methods do, and achieve higher Recall and Dice Score, on average, 97% and 96%, respectively. Higher Recall is particularly essential on features extraction and classification of VCFs. Therefore, FINE speeds up the manual annotation process while allowing more accurate semiautomatic segmentation.

[1]  Jeffrey C. Wang,et al.  Evaluation of foraminal cross-sectional area in lumbar spondylolisthesis using kinematic MRI , 2018, European Journal of Orthopaedic Surgery & Traumatology.

[2]  Marcello Henrique Nogueira-Barbosa,et al.  3DBGrowth: Volumetric Vertebrae Segmentation and Reconstruction in Magnetic Resonance Imaging , 2019, 2019 IEEE 32nd International Symposium on Computer-Based Medical Systems (CBMS).

[3]  Zhi-peng Wang,et al.  Biomechanical effects of different vertebral heights after augmentation of osteoporotic vertebral compression fracture: a three-dimensional finite element analysis , 2018, Journal of Orthopaedic Surgery and Research.

[4]  L. Rodney Long,et al.  Bridging the Gap: Enabling CBIR in Medical Applications , 2008, 2008 21st IEEE International Symposium on Computer-Based Medical Systems.

[5]  F. Massey The Kolmogorov-Smirnov Test for Goodness of Fit , 1951 .

[6]  V. Naganathan,et al.  Management of vertebral compression fracture in general practice: BEACH program , 2017, PloS one.

[7]  Vladimir Vezhnevets,et al.  “GrowCut” - Interactive Multi-Label N-D Image Segmentation By Cellular Automata , 2005 .

[8]  Marcello Henrique Nogueira-Barbosa,et al.  BGrowth: an efficient approach for the segmentation of vertebral compression fractures in magnetic resonance imaging , 2019, SAC.

[9]  Christopher Nimsky,et al.  Vertebral body segmentation with GrowCut: Initial experience, workflow and practical application , 2017, SAGE open medicine.

[10]  Ron Kikinis,et al.  An Effective Interactive Medical Image Segmentation Method Using Fast GrowCut , 2014 .

[11]  Matthew J Zdilla,et al.  Circularity, Solidity, Axes of a Best Fit Ellipse, Aspect Ratio, and Roundness of the Foramen Ovale: A Morphometric Analysis With Neurosurgical Considerations , 2016, The Journal of craniofacial surgery.