An evaluation of the polymorphisms Ins16bp and Arg72Pro in p53 as breast cancer risk modifiers in BRCA1 and BRCA2 mutation carriers

[1]  F. Schmitt,et al.  Importance of TP53 codon 72 and intron 3 duplication 16bp polymorphisms in prediction of susceptibility on breast cancer , 2008, BMC Cancer.

[2]  J. Peterse,et al.  Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer , 2007, Proceedings of the National Academy of Sciences.

[3]  Georgia Chenevix-Trench,et al.  An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA) , 2007, Breast Cancer Research.

[4]  Alison M Dunning,et al.  Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk , 2007, Breast Cancer Research.

[5]  Jinko Graham,et al.  hapassoc: Software for Likelihood Inference of Trait Associations with SNP Haplotypes and Other Attributes , 2006 .

[6]  M. Urioste,et al.  A haplotype containing the p53 polymorphisms Ins16bp and Arg72Pro modifies cancer risk in BRCA2 mutation carriers , 2006, Human mutation.

[7]  J. Chang-Claude,et al.  A weighted cohort approach for analysing factors modifying disease risks in carriers of high‐risk susceptibility genes , 2005, Genetic epidemiology.

[8]  P. Ongusaha,et al.  BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest , 2003, Oncogene.

[9]  T. Rebbeck,et al.  Germline TP53 mutations in breast cancer families with multiple primary cancers: is TP53 a modifier of BRCA1? , 2003, Journal of Medical Genetics.

[10]  M. Murphy,et al.  The codon 72 polymorphic variants of p53 have markedly different apoptotic potential , 2003, Nature Genetics.

[11]  E. Imyanitov,et al.  Evidence against involvement of p53 polymorphism in breast cancer predisposition , 2003, International journal of cancer.

[12]  M. Spitz,et al.  p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity. , 2002, Journal of the National Cancer Institute.

[13]  E. Biros,et al.  A link between the p53 germ line polymorphisms and white blood cells apoptosis in lung cancer patients. , 2002, Lung cancer.

[14]  A. Berns,et al.  Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer , 2001, Nature Genetics.

[15]  T. Rebbeck,et al.  p53 germline polymorphisms are associated with an increased risk for breast cancer in German women. , 1998, Anticancer research.

[16]  I. Bleiweiss,et al.  p53 haplotype determination in breast cancer. , 1997, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[17]  A. P. Damin,et al.  Evidence for an association of TP53 codon 72 polymorphism with breast cancer risk. , 2006, Cancer detection and prevention.

[18]  P. J. Huber The behavior of maximum likelihood estimates under nonstandard conditions , 1967 .