Eye-head co-ordination in patients with Parkinsonism and cerebellar ataxia.

Eye-head co-ordination of patients with Parkinsonism and cerebellar ataxia was investigated and compared with that of normal subjects. In Parkinsonian patients eye-head co-ordination was of the same pattern as normals, with an accurate and stable gaze. Reaction times for both eyes and head, however, were prolonged. It was also noted that the contribution of head movements to gaze shift was abnormally large and that the gaze accuracy was decreased when the head was immobilised. In patients with cerebellar ataxia, gaze was dysmetric, often hypermetric, and was unstable during head movements. The contribution of head movements to gaze was also large. It is concluded that Parkinsonism and cerebellar diseases influence eye-head co-ordination differently.

[1]  H. Shibasaki,et al.  Oculomotor abnormalities in Parkinson's disease. , 1979, Archives of neurology.

[2]  R D Yee,et al.  Visual‐vestibular interaction and cerebellar atrophy , 1979, Neurology.

[3]  R. Baloh,et al.  Eye-Tracking and Optokinetic Nystagmus , 1977, Annals of Otology, Rhinology and Laryngology.

[4]  L. Ritchie.  Effects of cerebellar lesions on saccadic eye movements. , 1976, Journal of neurophysiology.

[5]  L. Stark,et al.  Disorders in cerebellar ocular motor control. I. Saccadic overshoot dysmetria. An oculographic, control system and clinico-anatomical analysis. , 1976, Brain : a journal of neurology.

[6]  D. Robinson.  Adaptive gain control of vestibuloocular reflex by the cerebellum. , 1976, Journal of neurophysiology.

[7]  D G Cogan,et al.  Ocular motor abnormalities in hereditary cerebellar ataxia. , 1976, Brain : a journal of neurology.

[8]  V Honrubia,et al.  Vestibulo‐ocular function in patients with cerebellar atrophy , 1975, Neurology.

[9]  F. A. Miles,et al.  Adaptive plasticity in the vestibulo-ocular responses of the rhesus monkey. , 1974, Brain research.

[10]  E Bizzi,et al.  Two modes of active eye-head coordination in monkeys. , 1972, Brain research.

[11]  M. B. Bender,et al.  Oculomotor function in patients with Parkinson's disease. , 1972, Journal of the neurological sciences.

[12]  B. Cohen,et al.  Changes in saccadic eye movements produced by cerebellar cortical lesions. , 1971, Experimental neurology.

[13]  E. Bizzi,et al.  Eye-Head Coordination in Monkeys: Evidence for Centrally Patterned Organization , 1971, Science.

[14]  G. Jones,et al.  Akinesia, hypokinesia, and bradykinesia in the oculomotor system of patients with Parkinson's disease. , 1971, Experimental neurology.

[15]  G. Jones,et al.  Dynamic characteristics of saccadic eye movements in Parkinson's disease. , 1971, Experimental Neurology.

[16]  A. Bartz.  Eye and Head Movements in Peripheral Vision: Nature of Compensatory Eye Movements , 1966, Science.

[17]  Masao Ito,et al.  The Cerebellar Modification of Rabbit's Horizontal Vestibulo-Ocular Reflex Induced by Sustained Head Rotation Combined with Visual Stimulation , 1974 .

[18]  S. Ishikawa.  A new instrument for recording of the eye movement , 1973 .

[19]  R. Hassler.  Supranuclear structures regulating binocular eye and head movements. , 1972, Bibliotheca ophthalmologica : supplementa ad ophthalmologica.

[20]  B. Cohen,et al.  Changes in saccadic eye movements of patients with Parkinson's disease before and after L-dopa. , 1969, Transactions of the American Neurological Association.