Supraventricular tachycardias, conduction disease, and cardiomyopathy in 3 families with the same rare variant in TNNI3K (p.Glu768Lys).

[1]  P. Lambiase,et al.  Pathophysiology, diagnosis and treatment of tachycardiomyopathy , 2017, Heart.

[2]  C. Lien,et al.  Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration , 2017, Nature Genetics.

[3]  Salah S Al-Zaiti,et al.  Paroxysmal Supraventricular Tachycardia: Pathophysiology, Diagnosis, and Management. , 2016, Critical care nursing clinics of North America.

[4]  M. Helton Diagnosis and Management of Common Types of Supraventricular Tachycardia. , 2015, American family physician.

[5]  James Y. Zou Analysis of protein-coding genetic variation in 60,706 humans , 2015, Nature.

[6]  C. Bezzina,et al.  TNNI3K in cardiovascular disease and prospects for therapy. , 2015, Journal of molecular and cellular cardiology.

[7]  L. Aravind,et al.  Whole exome sequencing identifies the TNNI3K gene as a cause of familial conduction system disease and congenital junctional ectopic tachycardia. , 2015, International journal of cardiology.

[8]  Bale,et al.  Standards and Guidelines for the Interpretation of Sequence Variants: A Joint Consensus Recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology , 2015, Genetics in Medicine.

[9]  Michael T. Zimmermann,et al.  TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy. , 2014, Human molecular genetics.

[10]  A. P. Graves,et al.  Inhibition of the Cardiomyocyte-Specific Kinase TNNI3K Limits Oxidative Stress, Injury, and Adverse Remodeling in the Ischemic Heart , 2013, Science Translational Medicine.

[11]  R. Hui,et al.  TNNI3K, a Cardiac-Specific Kinase, Promotes Physiological Cardiac Hypertrophy in Transgenic Mice , 2013, PloS one.

[12]  D. Marchuk,et al.  Dissection of a Quantitative Trait Locus for PR Interval Duration Identifies Tnni3k as a Novel Modulator of Cardiac Conduction , 2012, PLoS genetics.

[13]  Christopher A. Miller,et al.  VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. , 2012, Genome research.

[14]  M. DePristo,et al.  A framework for variation discovery and genotyping using next-generation DNA sequencing data , 2011, Nature Genetics.

[15]  J. Shubrook,et al.  Common types of supraventricular tachycardia: diagnosis and management. , 2010, American family physician.

[16]  M. DePristo,et al.  The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. , 2010, Genome research.

[17]  Jan Menke,et al.  Thromboembolism in atrial fibrillation. , 2010, The American journal of cardiology.

[18]  T. Hadnott,et al.  Tnni3k Modifies Disease Progression in Murine Models of Cardiomyopathy , 2009, PLoS genetics.

[19]  Ken Chen,et al.  VarScan: variant detection in massively parallel sequencing of individual and pooled samples , 2009, Bioinform..

[20]  J. Ding,et al.  Identification of the dual specificity and the functional domains of the cardiac-specific protein kinase TNNI3K. , 2007, General physiology and biophysics.

[21]  D. Marchuk,et al.  QTL mapping in a mouse model of cardiomyopathy reveals an ancestral modifier allele affecting heart function and survival , 2005, Mammalian Genome.

[22]  D. Wilber,et al.  Influence of age and gender on the mechanism of supraventricular tachycardia. , 2004, Heart rhythm.

[23]  Ying-jie Wei,et al.  Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I , 2003, Journal of Molecular Medicine.

[24]  D. Marchuk,et al.  Genetic Modifier Loci Affecting Survival and Cardiac Function in Murine Dilated Cardiomyopathy , 2002, Circulation.

[25]  J. Strasburger,et al.  Supraventricular tachycardia mechanisms and their age distribution in pediatric patients. , 1992, The American journal of cardiology.

[26]  P. Brugada,et al.  Mechanisms of supraventricular tachycardia. , 1988, The American journal of cardiology.

[27]  D. Marchuk,et al.  Overexpression of TNNI3K, a cardiac-specific MAPKKK, promotes cardiac dysfunction. , 2013, Journal of molecular and cellular cardiology.

[28]  K. Wood Mechanisms and clinical manifestations of supraventricular tachycardias. , 1995, Progress in cardiovascular nursing.