Effects of high frequency repetitive transcranial magnetic stimulation on P300 event-related potentials

Abstract Objective : Auditory event-related potentials (P 300 -ERPs) were analyzed before and after repetitive transcranial magnetic stimulation (rTMS). Methods : Two rTMS trains (10 Hz, 3 s, 100% motor threshold and 5 min interval) were delivered over the left frontal area in healthy subjects. P 300 -ERPs were recorded at 14 electrode sites on the scalp using a typical oddball paradigm before and after rTMS. The latencies and amplitudes of N 100 , P 200 , N 200 and P 300 were measured and compared. The directed coherence (DCOH) was estimated to demonstrate information flow between different cortical areas. Results : rTMS significantly influenced P 300 -ERPs. The effects differed on the different components ( P 300 significantly increased after stimulation, which was more obvious in the frontal and central areas. The changes in P 300 amplitude were not significant ( P >0.05). The DCOH from the frontal, central, parietal and occipital areas to the temporal area was significantly higher than the DCOH from the temporal area to the former 4 areas ( P Conclusions : rTMS with the present parameters can affect P 300 -ERPs, leading to a delayed P 300 component and changes in information connections around the stimulated site. Our data suggest that rTMS may postpone neuronal activities related to cognitive processing.

[1]  Kiyotaka Yamamura,et al.  DECOMPOSITION METHOD AND ACCELERATION TECHNIQUES FOR A FIXED POINT ALGORITHM. , 1984 .

[2]  D Liberati,et al.  EEG coherence in Alzheimer's disease. , 1998, Electroencephalography and clinical neurophysiology.

[3]  J. Polich,et al.  Cognitive and biological determinants of P300: an integrative review , 1995, Biological Psychology.

[4]  M. Hallett,et al.  Use and safety of a new repetitive transcranial magnetic stimulator. , 1996, Electroencephalography and clinical neurophysiology.

[5]  L. Garcia-Larrea,et al.  Timing and characteristics of perceptual attenuation by transcranial stimulation: a study using magnetic cortical stimulation and somatosensory-evoked potentials. , 1999, Psychophysiology.

[6]  F Pierelli,et al.  Preprogramming and control activity of bimanual self-paced motor task in Parkinson's disease , 2000, Clinical Neurophysiology.

[7]  M Takigawa.  Rhythmic light therapy for depression and data processing analysis of its effects by directed coherence. , 1988, Activitas nervosa superior.

[8]  D Friedman,et al.  An overview of age-related changes in the scalp distribution of P3b. , 1997, Electroencephalography and clinical neurophysiology.

[9]  G. Wang,et al.  EEG analysis of epilepsy by directed coherence method. A data processing approach. , 1996, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[10]  K. Meador,et al.  Optimum stimulus parameters for lateralized suppression of speech with magnetic brain stimulation , 1996, Neurology.

[11]  T. Sejnowski,et al.  Functionally Independent Components of the Late Positive Event-Related Potential during Visual Spatial Attention , 1999, The Journal of Neuroscience.

[12]  Lower-bandpass filter frequency in P3 experiments: A possible cause for divergent results in schizophrenia research , 1990, Biological Psychiatry.

[13]  M Hallett,et al.  Safety of different inter-train intervals for repetitive transcranial magnetic stimulation and recommendations for safe ranges of stimulation parameters. , 1997, Electroencephalography and clinical neurophysiology.

[14]  L. Friberg,et al.  Speech localization using repetitive transcranial magnetic stimulation , 1994, Neurology.

[15]  H. Lüders,et al.  Identification of a negative bitemporal component (N300) of the event‐related potentials demonstrated by noncephalic recordings , 1988, Neurology.

[16]  D. Lehmann,et al.  Event-related potentials of the brain and cognitive processes: Approaches and applications , 1986, Neuropsychologia.

[17]  M. Ridding,et al.  Rapid rate transcranial magnetic stimulation--a safety study. , 1997, Electroencephalography and clinical neurophysiology.

[18]  D. Lehmann,et al.  Low resolution electromagnetic tomography: a new method for localizing electrical activity in the brain. , 1994, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[19]  Michael Erb,et al.  Sequential activation of supplementary motor area and primary motor cortex during self-paced finger movement in human evaluated by functional MRI , 1997, Neuroscience Letters.

[20]  J Valls-Solé,et al.  Safety of rapid-rate transcranial magnetic stimulation in normal volunteers. , 1993, Electroencephalography and clinical neurophysiology.

[21]  J. Covington,et al.  Neuropsychological performance and cognitive olfactory event-related brain potentials in young and elderly adults. , 1999, Journal of clinical and experimental neuropsychology.

[22]  M. Kaminski,et al.  Topographic analysis of coherence and propagation of EEG activity during sleep and wakefulness. , 1997, Electroencephalography and clinical neurophysiology.

[23]  C. Shagass,et al.  Evoked potential topography in major depression. I. Comparisons with nonpatients and schizophrenics. , 1992, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[24]  A. Fallgatter,et al.  Three-dimensional tomography of event-related potentials during response inhibition: evidence for phasic frontal lobe activation. , 1998, Electroencephalography and clinical neurophysiology.

[25]  I. Kwee,et al.  Sensory and cognitive evoked potentials in a case of congenital hydrocephalus. , 1987, Electroencephalography and clinical neurophysiology.

[26]  G Fein,et al.  Common reference coherence data are confounded by power and phase effects. , 1988, Electroencephalography and clinical neurophysiology.

[27]  Ulrich Hegerl,et al.  Dipole source analysis of P300 component of the auditory evoked potential: a methodological advance? , 1997, Psychiatry Research: Neuroimaging.

[28]  F L Bookstein,et al.  Identification of neural circuits underlying P300 abnormalities in schizophrenia. , 1999, Psychophysiology.

[29]  J. Kropotov,et al.  Subcortical neuronal correlates of component P300 in man. , 1991, Electroencephalography and clinical neurophysiology.

[30]  E. Koechlin,et al.  The role of the anterior prefrontal cortex in human cognition , 1999, Nature.

[31]  J C Shaw,et al.  An introduction to the coherence function and its use in EEG signal analysis. , 1981, Journal of medical engineering & technology.

[32]  E. Wassermann.  Risk and safety of repetitive transcranial magnetic stimulation: report and suggested guidelines from the International Workshop on the Safety of Repetitive Transcranial Magnetic Stimulation, June 5-7, 1996. , 1998, Electroencephalography and clinical neurophysiology.

[33]  E. Basar,et al.  Theta rhythmicities following expected visual and auditory targets. , 1992, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[34]  H. Möller,et al.  Late auditory evoked potentials (P300) do not discriminate between subgroups of alcohol-dependent patients defined by family history and antisocial personality traits. , 1999, European journal of medical research.

[35]  M Honda,et al.  The role of the hippocampus in auditory processing studied by event-related electric potentials and magnetic fields in epilepsy patients before and after temporal lobectomy. , 1999, Brain : a journal of neurology.

[36]  Á. Pascual-Leone,et al.  Transcranial magnetic stimulation in patients with epilepsy , 1991, Neurology.

[37]  Thomas Kammer,et al.  Are recognition deficits following occipital lobe TMS explained by raised detection thresholds? , 1998, Neuropsychologia.

[38]  Á. Pascual-Leone,et al.  Induction of speech arrest and counting errors with rapid‐rate transcranial magnetic stimulation , 1991, Neurology.

[39]  G. Wang,et al.  Directed coherence as a measure of interhemispheric correlation of EEG. , 1992, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[40]  D Passarelli,et al.  Rapid‐rate transcranial magnetic stimulation and hemispheric language dominance , 1994, Neurology.

[41]  C. Elger,et al.  Responses of the epileptic focus to transcranial magnetic stimulation. , 1991, Electroencephalography and clinical neurophysiology. Supplement.

[42]  S. Shapiro,et al.  A Comparative Study of Various Tests for Normality , 1968 .

[43]  A. Papanicolaou,et al.  Electric source localization of the auditory P300 agrees with magnetic source localization. , 1995, Electroencephalography and clinical neurophysiology.

[44]  George Fein,et al.  Representation of multi-channel evoked potential data using a dipole component model of intracranial generators: application to the auditory P300☆ , 1990 .

[45]  T. Demiralp,et al.  A model for P300 generation based on responses to near-threshold visual stimuli. , 1999, Brain research. Cognitive brain research.

[46]  H. Akaike.  A new look at the statistical model identification , 1974 .

[47]  E. Donchin,et al.  A componential analysis of the ERP elicited by novel events using a dense electrode array. , 1999, Psychophysiology.

[48]  M. Seyal,et al.  Suppression of spatial localization of a cutaneous stimulus following transcranial magnetic pulse stimulation of the sensorimotor cortex. , 1997, Electroencephalography and clinical neurophysiology.

[49]  Rumyana Kristeva-Feige,et al.  Oscillatory cortical activity and movement-related potentials in proximal and distal movements , 2000, Clinical Neurophysiology.

[50]  J. Covington,et al.  P300, stimulus intensity, and modality. , 1996, Electroencephalography and clinical neurophysiology.

[51]  V. Samar,et al.  Time–Frequency Analysis of Single-Sweep Event-Related Potentials by Means of Fast Wavelet Transform , 1999, Brain and Language.

[52]  A. Kimura,et al.  Transcranial magnetic stimulation-induced changes in EEG and responses recorded from the scalp of healthy humans. , 1997, Electroencephalography and clinical neurophysiology.

[53]  G. Deuschl,et al.  Recommendations for the practice of clinical neurophysiology: guidelines of the International Federation of Clinical Neurophysiology. , 1999, Electroencephalography and clinical neurophysiology. Supplement.

[54]  G. Wang,et al.  Correlation of alpha activity between the frontal and occipital cortex. , 1992, The Japanese journal of physiology.

[55]  D. Lykken,et al.  Two-year retest stability of eye tracking performance and a comparison of electro-oculographic and infrared recording techniques: evidence of EEG in the electro-oculogram. , 1981, Psychophysiology.

[56]  Kenneth M Heilman,et al.  Effects of left frontal transcranial magnetic stimulation on depressed mood, cognition, and corticomotor threshold , 1999, Biological Psychiatry.

[57]  H. Harashima,et al.  A time‐series analysis method based on the directed transinformation , 1984 .

[58]  Hongkui Jing,et al.  Observation of EEG coherence after repetitive transcranial magnetic stimulation , 2000, Clinical Neurophysiology.