Development of a computer tool to detect and classify nodules in ultrasound breast images

Due to the high incidence rate of breast cancer in women, many procedures have been developed to assist the diagnosis and early detection. Currently, ultrasonography has proved as a useful tool in distinguishing benign and malignant masses. In this context, the computer-aided diagnosis schemes have provided to the specialist a second opinion more accurately and reliably, minimizing the visual subjectivity between observers. Thus, we propose the application of an automatic detection method based on the use of the technique of active contour in order to show precisely the contour of the lesion and provide a better understanding of their morphology. For this, a total of 144 images of phantoms were segmented and submitted to morphological operations of opening and closing for smoothing the edges. Then morphological features were extracted and selected to work as input parameters for the neural classifier Multilayer Perceptron which obtained 95.34% correct classification of data and Az of 0.96.

[1]  A.C. Patrocinio,et al.  Investigation of clustered microcalcification features for an automated classifier as part of a mammography CAD scheme , 2000, Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Cat. No.00CH37143).

[2]  Hee Chan Kim,et al.  Computer-aided diagnosis of solid breast nodules on ultrasound with digital image processing and artificial neural network , 2004, The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[3]  Zainul Abdin Jaffery,et al.  Detection and Shape Feature Extraction of Breast Tumor in Mammograms , 2012 .

[4]  Linlin Zhu,et al.  Two-step active contour method based on gradient flow , 2010, Ind. Robot.

[5]  Guojun Lu,et al.  Review of shape representation and description techniques , 2004, Pattern Recognit..

[6]  Ruey-Feng Chang,et al.  Automatic ultrasound segmentation and morphology based diagnosis of solid breast tumors , 2004, Breast Cancer Research and Treatment.

[7]  Kpalma Kidiyo,et al.  A Survey of Shape Feature Extraction Techniques , 2008 .

[8]  A.F.C. Infantosi,et al.  Classification of breast tumours on ultrasound images using morphometric parameters , 2005, IEEE International Workshop on Intelligent Signal Processing, 2005..

[9]  André Victor Alvarenga,et al.  Breast Ultrasound Segmentation Using Morphologic Operators and a Gaussian Function Constraint , 2008 .

[10]  A. Thomas Stavros New Advances in Breast Ultrasound: Computer-Aided Detection , 2009 .

[11]  Simon Haykin,et al.  Neural Networks and Learning Machines , 2010 .

[12]  Tryphon T. Georgiou,et al.  A new distribution metric for image segmentation , 2008, SPIE Medical Imaging.

[13]  Eran A. Edirisinghe,et al.  A comparative study in ultrasound breast imaging classification , 2009, Medical Imaging.

[14]  Antonio Adilton Oliveira Carneiro,et al.  Quantitative evaluation of automatic methods for lesions detection in breast ultrasound images , 2013, Medical Imaging.

[15]  J. IIVARINENHelsinki Efficiency of Simple Shape Descriptors , 1997 .