DMP1 Depletion Decreases Bone Mineralization In Vivo: An FTIR Imaging Analysis

The role of DMP1 in mineralization was analyzed by comparing bone mineral and matrix properties in dmp1‐null female mice to heterozygous and wildtype controls by FTIR imaging spectroscopy. The observed decreased mineral content in dmp1 null mice indicates a key role for dmp1 in bone mineralization. Indirect effects of DMP1 on other systems also determine the KO phenotype.

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