Deepmole: Deep neural networks for skin mole lesion classification

Nowadays, the occurrence of skin cancer cases has grown worldwide due to the extended exposure to the harmful radiation from the Sun. Most common approach to detect the malignancy of skin moles is by visual inspection performed by an expert dermatologist, using a set of specific clinical rules. Computer-aided diagnosis, based on skin mole imaging, is another concurrent method which has experienced major advancements due to improvement of imaging sensors and processing power. However, these schemes use hand-crafted features which are difficult to tune and perform poorly on new cases due to lack of generalization power. In this study we present a method that use a pretrained deep neural network (DNN) to automatically extract a set of representative features that can be later used to diagnose a sample of skin lesion for malignancy. The experimental tests carried out on a clinical dataset show that the classification performance using DNN-based features performs better than the state-of-the-art techniques.

[1]  R. H. Moss,et al.  Neural network diagnosis of malignant melanoma from color images , 1994, IEEE Transactions on Biomedical Engineering.

[2]  Masaru Tanaka,et al.  Four-Class Classification of Skin Lesions With Task Decomposition Strategy , 2015, IEEE Transactions on Biomedical Engineering.

[3]  Chris T. Kiranoudis,et al.  Automated skin lesion assessment using mobile technologies and cloud platforms , 2012, 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[4]  Ngai-Man Cheung,et al.  Early melanoma diagnosis with mobile imaging , 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[5]  Fabio A. González,et al.  Automatic detection of invasive ductal carcinoma in whole slide images with convolutional neural networks , 2014, Medical Imaging.

[6]  Yoshua Bengio,et al.  How transferable are features in deep neural networks? , 2014, NIPS.

[7]  John Collins,et al.  A cascade classifier for diagnosis of melanoma in clinical images , 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[8]  G. Argenziano,et al.  Epiluminescence microscopy for the diagnosis of doubtful melanocytic skin lesions. Comparison of the ABCD rule of dermatoscopy and a new 7-point checklist based on pattern analysis. , 1998, Archives of dermatology.

[9]  Saeed Setayeshi,et al.  Computer-aided diagnosis (CAD) of the skin disease based on an intelligent classification of sonogram using neural network , 2012, Neural Computing and Applications.

[10]  Aurora Sáez,et al.  Model-Based Classification Methods of Global Patterns in Dermoscopic Images , 2014, IEEE Transactions on Medical Imaging.

[11]  John Paoli,et al.  Smartphone teledermoscopy referrals: a novel process for improved triage of skin cancer patients. , 2015, Acta dermato-venereologica.

[12]  Rui Hu,et al.  Implementation of the 7-point checklist for melanoma detection on smart handheld devices , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[13]  David A. Clausi,et al.  High-Level Intuitive Features (HLIFs) for Intuitive Skin Lesion Description , 2015, IEEE Transactions on Biomedical Engineering.

[14]  S. Menzies,et al.  A sensitivity and specificity analysis of the surface microscopy features of invasive melanoma , 1996, Melanoma research.

[15]  Geoffrey E. Hinton,et al.  ImageNet classification with deep convolutional neural networks , 2012, Commun. ACM.

[16]  Trevor Darrell,et al.  Caffe: Convolutional Architecture for Fast Feature Embedding , 2014, ACM Multimedia.

[17]  Ilias Maglogiannis,et al.  Overview of Advanced Computer Vision Systems for Skin Lesions Characterization , 2009, IEEE Transactions on Information Technology in Biomedicine.

[18]  Jorge S. Marques,et al.  Two Systems for the Detection of Melanomas in Dermoscopy Images Using Texture and Color Features , 2014, IEEE Systems Journal.

[19]  Yi Shang,et al.  A Mobile Automated Skin Lesion Classification System , 2011, 2011 IEEE 23rd International Conference on Tools with Artificial Intelligence.

[20]  Ashfaq A Marghoob,et al.  The complexity of diagnosing melanoma. , 2009, The Journal of investigative dermatology.

[21]  Helmut Bölcskei,et al.  Deep convolutional neural networks based on semi-discrete frames , 2015, 2015 IEEE International Symposium on Information Theory (ISIT).

[22]  Peter Gardner,et al.  Automated high-throughput assessment of prostate biopsy tissue using infrared spectroscopic chemical imaging , 2014, Medical Imaging.