Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy
暂无分享,去创建一个
Euan A. Ashley | Michael T. Longaker | Oscar J. Abilez | Shin Lin | Michael P. Snyder | Veronica Sanchez-Freire | Rui Chen | Manish J. Butte | Masayuki Yazawa | Robert C. Robbins | Li Wang | Rui Chen | E. Ashley | R. Dolmetsch | A. Pavlovic | Shin Lin | M. Snyder | M. Longaker | R. Hajjar | M. Butte | O. Abilez | Joseph C. Wu | Shijun Hu | A. Lee | R. Robbins | N. Sun | M. Yazawa | Aleksandra Pavlovic | Roger J. Hajjar | Ricardo E. Dolmetsch | Shijun Hu | Ning Sun | Andrew Lee | V. Sanchez-Freire | Enrique G. Navarrete | Jianwei Liu | Leng Han | Jianwei Liu | Leng Han | Li Wang | Ning Sun | Veronica Sanchez-Freire
[1] Barry J Maron,et al. Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interd , 2006, Circulation.
[2] A. Bayés‐Genís,et al. Vascular dysfunction in idiopathic dilated cardiomyopathy , 2009, Nature Reviews Cardiology.
[3] Minoru Hongo,et al. MLP-Deficient Mice Exhibit a Disruption of Cardiac Cytoarchitectural Organization, Dilated Cardiomyopathy, and Heart Failure , 1997, Cell.
[4] J. Potter,et al. Clinical and Functional Characterization of TNNT2 Mutations Identified in Patients With Dilated Cardiomyopathy , 2009, Circulation. Cardiovascular genetics.
[5] Deepak M. Gupta,et al. Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells , 2009, Proceedings of the National Academy of Sciences.
[6] J. De Sutter,et al. Dilated cardiomyopathy caused by a novel TNNT2 mutation-added value of genetic testing in the correct identification of affected subjects. , 2010, International journal of cardiology.
[7] N. Moins,et al. Paradoxal pharmacologic effects observed withβ-blocker agents on cardiac cells in culture , 1991, In Vitro Cellular & Developmental Biology - Animal.
[8] Lior Gepstein,et al. Modelling the long QT syndrome with induced pluripotent stem cells , 2011, Nature.
[9] U. Schmidt,et al. Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a. , 1999, Circulation.
[10] Lei Yang,et al. Patient-specific induced pluripotent stem cell derived models of LEOPARD syndrome , 2010, Nature.
[11] M. Guidinger,et al. Pediatric transplantation, 1994–2003 , 2005, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[12] J. Carroll,et al. Physiologic mechanisms governing hemodynamic responses to positive inotropic therapy in patients with dilated cardiomyopathy. , 1988, Circulation.
[13] J. Schaper,et al. Deposition of nonsarcomeric alpha-actinin in cardiomyocytes from patients with dilated cardiomyopathy or chronic pressure overload. , 2009, Experimental and clinical cardiology.
[14] Siegfried Labeit,et al. Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease. , 2009, Journal of molecular and cellular cardiology.
[15] R. Hershberger,et al. Clinical and genetic issues in familial dilated cardiomyopathy. , 2005, Journal of the American College of Cardiology.
[16] T. Toyofuku,et al. SR Ca2+-ATPase/phospholamban incardiomyocyte function , 1996 .
[17] T. Toyofuku,et al. SR Ca(2+)-ATPase/phospholamban in cardiomyocyte function. , 1996, Journal of cardiac failure.
[18] F. Waagstein,et al. Improved exercise hemodynamic status in dilated cardiomyopathy after beta-adrenergic blockade treatment. , 1994, Journal of the American College of Cardiology.
[19] Masahiko Hoshijima,et al. The Cardiac Mechanical Stretch Sensor Machinery Involves a Z Disc Complex that Is Defective in a Subset of Human Dilated Cardiomyopathy , 2002, Cell.
[20] Barry Greenberg,et al. Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): A Phase 2 Trial of Intracoronary Gene Therapy of Sarcoplasmic Reticulum Ca2+-ATPase in Patients With Advanced Heart Failure , 2011, Circulation.
[21] Stephen H. Smith,et al. The Role of Cardiac Troponin T Quantity and Function in Cardiac Development and Dilated Cardiomyopathy , 2008, PloS one.
[22] Jonathan Seidman,et al. Genetic causes of human heart failure. , 2005, The Journal of clinical investigation.
[23] D. Fatkin,et al. Effects of Mechanical Stress and Carvedilol in Lamin A/C–Deficient Dilated Cardiomyopathy , 2010, Circulation research.
[24] Sean P. Palecek,et al. Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells , 2009, Circulation research.
[25] J. Sadoshima,et al. Myosin light chain kinase mediates sarcomere organization during cardiac hypertrophy in vitro , 2000, Nature Medicine.
[26] Wolfgang J. Parak,et al. Mapping the mechanical pulse of single cardiomyocytes with the atomic force microscope , 1999, European Biophysics Journal.
[27] A. Marian,et al. Differential interactions of thin filament proteins in two cardiac troponin T mouse models of hypertrophic and dilated cardiomyopathies. , 2008, Cardiovascular research.
[28] H. Ly,et al. Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure. , 2008, Journal of the American College of Cardiology.
[29] A. Gomes,et al. Mutations in Troponin that cause HCM, DCM AND RCM: what can we learn about thin filament function? , 2010, Journal of molecular and cellular cardiology.
[30] Yoshiaki Kawase,et al. Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure. , 2008, Journal of cardiac failure.
[31] K. Chien,et al. Stress Pathways and Heart Failure , 1999, Cell.
[32] J. Guerrero,et al. Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[33] Didier Y. R. Stainier,et al. Cardiac troponin T is essential in sarcomere assembly and cardiac contractility , 2002, Nature Genetics.
[34] LimorZwi,et al. Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells , 2009 .
[35] Karl-Ludwig Laugwitz,et al. Patient-specific induced pluripotent stem-cell models for long-QT syndrome. , 2010, New England Journal of Medicine.
[36] Eric D. Adler,et al. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population , 2008, Nature.
[37] S. Morimoto. Molecular pathogenic mechanisms of cardiomyopathies caused by mutations in cardiac troponin T. , 2007, Advances in experimental medicine and biology.
[38] R. Hajjar,et al. Sarcoplasmic reticulum Ca2+ ATPase as a therapeutic target for heart failure , 2010, Expert opinion on biological therapy.
[39] F. Takahashi‐Yanaga,et al. Ca2+-desensitizing effect of a deletion mutation ΔK210 in cardiac troponin T that causes familial dilated cardiomyopathy , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[40] S. Dhein,et al. Cardiac Gap Junction Channels Are Upregulated by Metoprolol: An Unexpected Effect of Beta-Blockers , 2010, Pharmacology.
[41] Joseph A. Hill,et al. Hic-5 is required for fetal gene expression and cytoskeletal organization of neonatal cardiac myocytes. , 2009, Journal of molecular and cellular cardiology.
[42] Jonathan A. Bernstein,et al. Using iPS cells to investigate cardiac phenotypes in patients with Timothy Syndrome , 2011, Nature.
[43] D. Bers. Cardiac excitation–contraction coupling , 2002, Nature.
[44] M. Yano,et al. Altered intracellular Ca2+ handling in heart failure. , 2005, The Journal of clinical investigation.
[45] W. Rottbauer,et al. Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy , 2009, Nature Medicine.
[46] R. Gunnar,et al. Improvement in symptoms and exercise tolerance by metoprolol in patients with dilated cardiomyopathy: a double-blind, randomized, placebo-controlled trial. , 1985, Circulation.
[47] T. Graf. Faculty Opinions recommendation of Induction of pluripotent stem cells from adult human fibroblasts by defined factors. , 2007 .
[48] F. Takahashi‐Yanaga,et al. Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization. , 2003, Journal of molecular and cellular cardiology.
[49] B. Thiers. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2008 .
[50] R. Stewart,et al. Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , 2007, Science.