Mitochondrial determinants of cancer health disparities.
暂无分享,去创建一个
[1] A. Prakash,et al. DNA damage related crosstalk between the nucleus and mitochondria. , 2017, Free radical biology & medicine.
[2] H. Tiwari,et al. Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma , 2017, Genome Medicine.
[3] Taylor K. Dunivin,et al. Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome. , 2016, Toxicology and applied pharmacology.
[4] A. Neugut,et al. Polymorphisms in DNA repair genes, traffic‐related polycyclic aromatic hydrocarbon exposure and breast cancer incidence , 2016, International journal of cancer.
[5] J. Neuzil,et al. The role of Her2 and other oncogenes of the PI3K/AKT pathway in mitochondria , 2016, Biological chemistry.
[6] U. Jensen,et al. Identification of eight novel SDHB, SDHC, SDHD germline variants in Danish pheochromocytoma/paraganglioma patients , 2016, Hereditary cancer in clinical practice.
[7] P. Nallari,et al. Association of estrogen and progesterone receptor gene polymorphisms and their respective hormones in uterine leiomyomas , 2016, Tumor Biology.
[8] Q. Peng,et al. MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features , 2016, Oncotarget.
[9] L. Torres-Sánchez,et al. Androgen receptor CAG polymorphism and sporadic and early-onset prostate cancer among Mexican men , 2016, Journal of Human Genetics.
[10] D. Rojano-Mejía,et al. Genetic variants in ATP6 and ND3 mitochondrial genes are not associated with aggressive prostate cancer in Mexican–Mestizo men with overweight or obesity , 2016, The aging male : the official journal of the International Society for the Study of the Aging Male.
[11] G. Sethi,et al. Synthetic Lethality of a Novel Small Molecule Against Mutant KRAS-Expressing Cancer Cells Involves AKT-Dependent ROS Production. , 2016, Antioxidants & redox signaling.
[12] S. Dhar,et al. Mitochondrial dysfunction-mediated apoptosis resistance associates with defective heat shock protein response in African–American men with prostate cancer , 2016, British Journal of Cancer.
[13] R. Kitazawa,et al. TDRG1 regulates chemosensitivity of seminoma TCam-2 cells to cisplatin via PI3K/Akt/mTOR signaling pathway and mitochondria-mediated apoptotic pathway , 2016, Cancer biology & therapy.
[14] Shih-Cheng Chang,et al. NRAS germline variant G138R and multiple rare somatic mutations on APC in colorectal cancer patients in Taiwan by next generation sequencing , 2016, Oncotarget.
[15] S. Lim,et al. Regulation of mitochondrial functions by protein phosphorylation and dephosphorylation , 2016, Cell & Bioscience.
[16] L. Orozco,et al. The rs61764370 Functional Variant in the KRAS Oncogene is Associated with Chronic Myeloid Leukemia Risk in Women. , 2016, Asian Pacific journal of cancer prevention : APJCP.
[17] Jung Weon Lee,et al. Potential role of 8-oxoguanine DNA glycosylase 1 as a STAT1 coactivator in endotoxin-induced inflammatory response. , 2016, Free radical biology & medicine.
[18] W. Min,et al. Mitochondrial Redox Signaling and Tumor Progression , 2016, Cancers.
[19] Yanlv Ren,et al. MiR-485-3p and miR-485-5p suppress breast cancer cell metastasis by inhibiting PGC-1α expression , 2016, Cell Death and Disease.
[20] J. Demoulin,et al. FOXO transcription factors in cancer development and therapy , 2016, Cellular and Molecular Life Sciences.
[21] Cristiano Noto,et al. The role of oxidative and nitrosative stress in accelerated aging and major depressive disorder , 2016, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[22] S. Datta,et al. Association of DNA sequence variation in mitochondrial DNA polymerase with mitochondrial DNA synthesis and risk of oral cancer. , 2016, Gene.
[23] A. Whitmarsh,et al. Mitochondrial Proteins Moonlighting in the Nucleus. , 2015, Trends in biochemical sciences.
[24] S. Murphy,et al. Mitochondrial Superoxide Dismutase Has a Protumorigenic Role in Ovarian Clear Cell Carcinoma. , 2015, Cancer research.
[25] Yun Zhang,et al. Mutant p53: Multiple Mechanisms Define Biologic Activity in Cancer , 2015, Front. Oncol..
[26] Cole M. Haynes,et al. UPR(mt)-mediated cytoprotection and organismal aging. , 2015, Biochimica et biophysica acta.
[27] R. Zeillinger,et al. HER2 Codon 655 (Ile/Val) Polymorphism and Breast Cancer in Austrian Women. , 2015, Anticancer research.
[28] Q. Fan,et al. The androgen receptor cytosine-adenine-guanine repeat length contributes to the development of epithelial ovarian cancer , 2015, Oncotarget.
[29] H. Tiwari,et al. Mitochondrial DNA Polymerase POLG1 Disease Mutations and Germline Variants Promote Tumorigenic Properties , 2015, PloS one.
[30] P. Dítě,et al. Comparison of the prevalence of KRAS-LCS6 polymorphism (rs61764370) within different tumour types (colorectal, breast, non-small cell lung cancer and brain tumours). A study of the Czech population. , 2015, Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia.
[31] Keshav K. Singh. MIPIGENETICS and MIPIGENOMICS: Integrating mitochondria-induced mayhem contributing to mystondria , 2015 .
[32] Austin L. Brown,et al. SOD2 genetic variant associated with treatment-related ototoxicity in cisplatin-treated pediatric medulloblastoma , 2015, Cancer medicine.
[33] E. Friedman,et al. DNA Base-Excision Repair Genes OGG1 and NTH1 in Brazilian Lung Cancer Patients , 2015, Molecular Diagnosis & Therapy.
[34] A. Peters,et al. Evaluation of IDH1G105 polymorphism as prognostic marker in intermediate-risk AML , 2015, Annals of Hematology.
[35] Sung Hak Kim,et al. Ras-mediated modulation of pyruvate dehydrogenase activity regulates mitochondrial reserve capacity and contributes to glioblastoma tumorigenesis. , 2015, Neuro-oncology.
[36] Z. Huo,et al. Androgen receptor (CAG)n polymorphisms and breast cancer risk in a Han Chinese population. , 2015, Genetics and molecular research : GMR.
[37] S. Woo,et al. SIRT1 deacetylates and stabilizes hypoxia-inducible factor-1α (HIF-1α) via direct interactions during hypoxia. , 2015, Biochemical and biophysical research communications.
[38] T. Stokke,et al. Mitochondrial DNA Deficiency in Ovarian Cancer Cells and Cancer Stem Cell-like Properties. , 2015, Anticancer research.
[39] M. Gallegos-Arreola,et al. Association of the Alu insertion polymorphism in the progesterone receptor gene with breast cancer in a Mexican population , 2015, Archives of medical science : AMS.
[40] M. Jia,et al. Gene mutations in the D-loop region of mitochondrial DNA in oral squamous cell carcinoma. , 2015, Molecular medicine reports.
[41] Jin-Ching Lin,et al. Impact of Somatic Mutations in the D-Loop of Mitochondrial DNA on the Survival of Oral Squamous Cell Carcinoma Patients , 2015, PloS one.
[42] H. Rashid,et al. Evaluation of the p53 Arg72Pro polymorphism and its association with cancer risk: a HuGE review and meta-analysis. , 2015, Genetics research.
[43] P. Lambin,et al. How do changes in the mtDNA and mitochondrial dysfunction influence cancer and cancer therapy? Challenges, opportunities and models. , 2015, Mutation research. Reviews in mutation research.
[44] J. Auwerx,et al. The mitochondrial unfolded protein response—synchronizing genomes. , 2015, Current opinion in cell biology.
[45] Danica Chen,et al. A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging , 2015, Science.
[46] J. Luk,et al. SOD2 rs4880 CT/CC genotype predicts poor survival for Chinese gastric cancer patients received platinum and fluorouracil based adjuvant chemotherapy. , 2015, American journal of translational research.
[47] Robert A. Egnatchik,et al. Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth. , 2015, Cancer cell.
[48] L. Cai,et al. Single nucleotide polymorphisms in non-coding region of the glucocorticoid receptor gene and prednisone response in childhood acute lymphoblastic leukemia , 2015, Leukemia & lymphoma.
[49] U. Engelke,et al. Genotype-specific differences in the tumor metabolite profile of pheochromocytoma and paraganglioma using untargeted and targeted metabolomics. , 2015, The Journal of clinical endocrinology and metabolism.
[50] J. Gu,et al. Mitochondrial DNA copy number in peripheral blood leukocytes and the risk of clear cell renal cell carcinoma. , 2015, Carcinogenesis.
[51] L. Meng,et al. Polymorphisms of progesterone receptor and ovarian cancer risk: A systemic review and meta‐analysis , 2015, The journal of obstetrics and gynaecology research.
[52] H. Yacoub,et al. New haplotypes of the ATP synthase subunit 6 gene of mitochondrial DNA are associated with acute lymphoblastic leukemia in Saudi Arabia. , 2015, Asian Pacific journal of cancer prevention : APJCP.
[53] R. Carstens,et al. Mitochondrial retrograde signaling induces epithelial–mesenchymal transition and generates breast cancer stem cells , 2014, Oncogene.
[54] S. Mitra,et al. Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function , 2014, Nucleic acids research.
[55] J. Neuzil,et al. MicroRNA-126 suppresses mesothelioma malignancy by targeting IRS1 and interfering with the mitochondrial function. , 2014, Antioxidants & redox signaling.
[56] J. Neuzil,et al. MicroRNA regulation of cancer metabolism: role in tumour suppression. , 2014, Mitochondrion.
[57] R. Kalluri,et al. Corrigendum: PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis , 2014, Nature Cell Biology.
[58] J. Ji,et al. Genetic variations in IDH gene as prognosis predictors in TACE-treated hepatocellular carcinoma patients , 2014, Medical Oncology.
[59] Keshav K. Singh,et al. Global Genetic Determinants of Mitochondrial DNA Copy Number , 2014, PloS one.
[60] R. Kalluri,et al. PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation to promote metastasis , 2014, Nature Cell Biology.
[61] N. Buroker. Regulatory SNPs and transcriptional factor binding sites in ADRBK1, AKT3, ATF3, DIO2, TBXA2R and VEGFA , 2014, Transcription.
[62] N. Pendleton,et al. Androgen Receptor Polymorphism-Dependent Variation in Prostate-Specific Antigen Concentrations of European Men , 2014, Cancer Epidemiology, Biomarkers & Prevention.
[63] E. Michelakis,et al. A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation , 2014, Cell.
[64] G. Cavalli,et al. Oncogene-Induced Senescence as a New Mechanism of Disease: The Paradigm of Erdheim–Chester Disease , 2014, Front. Immunol..
[65] K. Attwood,et al. Androgen Receptor Mutations and Polymorphisms in African American Prostate Cancer , 2014, International journal of biological sciences.
[66] K. Shroyer,et al. Differential expression of miRNAs in colon cancer between African and Caucasian Americans: Implications for cancer racial health disparities , 2014, International journal of oncology.
[67] C. Neeley,et al. Mitochondrial Matrix Ca2+ Accumulation Regulates Cytosolic NAD+/NADH Metabolism, Protein Acetylation, and Sirtuin Expression , 2014, Molecular and Cellular Biology.
[68] A. Maitra,et al. miR-181c Regulates the Mitochondrial Genome, Bioenergetics, and Propensity for Heart Failure In Vivo , 2014, PloS one.
[69] P. Pinton,et al. H-Ras-driven tumoral maintenance is sustained through caveolin-1-dependent alterations in calcium signaling , 2014, Oncogene.
[70] J. Wilczyński,et al. Mitochondrial dysfunction in cancer , 2014, Przeglad menopauzalny = Menopause review.
[71] Feng Xu,et al. microRNA-200a inhibits cell proliferation by targeting mitochondrial transcription factor A in breast cancer. , 2014, DNA and cell biology.
[72] C. Chi,et al. Somatic alterations in mitochondrial DNA and mitochondrial dysfunction in gastric cancer progression. , 2014, World journal of gastroenterology.
[73] Ting Liu,et al. Progesterone receptor PROGINS and +331G/A polymorphisms confer susceptibility to ovarian cancer: a meta-analysis based on 17 studies , 2014, Tumor Biology.
[74] Matthew E. Welsch,et al. Regulation of Ferroptotic Cancer Cell Death by GPX4 , 2014, Cell.
[75] P. Leppert,et al. Expression of a mitochondrial progesterone receptor (PR-M) in leiomyomata and association with increased mitochondrial membrane potential. , 2014, The Journal of clinical endocrinology and metabolism.
[76] K. Kohn,et al. SIRT1/PARP1 crosstalk: connecting DNA damage and metabolism , 2013, Genome Integrity.
[77] Arnima Bhasin,et al. Combined targeting of PDK1 and EGFR triggers regression of glioblastoma by reversing the Warburg effect. , 2013, Cancer research.
[78] Michael G. Miller,et al. A 6-month observational study of energy, sexual desire, and body proportions in hypogonadal men treated with a testosterone 1% gel , 2013, The aging male : the official journal of the International Society for the Study of the Aging Male.
[79] E. Verdin,et al. SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK , 2013, Aging.
[80] Y. Liu,et al. Correlation between superoxide dismutase 1 and 2 polymorphisms and susceptibility to oral squamous cell carcinoma , 2013, Experimental and therapeutic medicine.
[81] N. Le,et al. Inherited common variants in mitochondrial DNA and invasive serous epithelial ovarian cancer risk , 2013, BMC Research Notes.
[82] Keshav K. Singh,et al. Reduced Mitochondrial DNA Content Associates with Poor Prognosis of Prostate Cancer in African American Men , 2013, PloS one.
[83] E. Bonora,et al. Oncocytic glioblastoma: a glioblastoma showing oncocytic changes and increased mitochondrial DNA copy number. , 2013, Human pathology.
[84] D. Parmar,et al. Association of polymorphism in cytochrome P450 2C9 with susceptibility to head and neck cancer and treatment outcome☆ , 2013, Applied & translational genomics.
[85] Yoshihiro Suzuki-Karasaki,et al. Mitochondrial superoxide mediates mitochondrial and endoplasmic reticulum dysfunctions in TRAIL-induced apoptosis in Jurkat cells. , 2013, Free radical biology & medicine.
[86] J. Cuezva,et al. Mitochondria-mediated energy adaption in cancer: the H(+)-ATP synthase-geared switch of metabolism in human tumors. , 2013, Antioxidants & redox signaling.
[87] S. Miyamoto,et al. Akt Phosphorylates HK-II at Thr-473 and Increases Mitochondrial HK-II Association to Protect Cardiomyocytes* , 2013, The Journal of Biological Chemistry.
[88] T. Shlomi,et al. A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence , 2013, Nature.
[89] C. Creighton,et al. Crosstalk from Non-Cancerous Mitochondria Can Inhibit Tumor Properties of Metastatic Cells by Suppressing Oncogenic Pathways , 2013, PloS one.
[90] J. Timmis,et al. Cytoplasmic Organelle DNA Preferentially Inserts into Open Chromatin , 2013, Genome biology and evolution.
[91] Lukas D. Osborne,et al. HIF1α and HIF2α independently activate SRC to promote melanoma metastases. , 2013, The Journal of clinical investigation.
[92] D. Winge,et al. Emerging concepts in the flavinylation of succinate dehydrogenase. , 2013, Biochimica et biophysica acta.
[93] T. Dwight,et al. Familial SDHA mutation associated with pituitary adenoma and pheochromocytoma/paraganglioma. , 2013, The Journal of clinical endocrinology and metabolism.
[94] Sara E. Miller,et al. A truncated progesterone receptor (PR-M) localizes to the mitochondrion and controls cellular respiration. , 2013, Molecular endocrinology.
[95] Y. Liu,et al. Characteristics and neural-like differentiation of mesenchymal stem cells derived from foetal porcine bone marrow , 2013, Bioscience reports.
[96] W. Kolch,et al. The Differential Effects of Wild-Type and Mutated K-Ras on MST2 Signaling Are Determined by K-Ras Activation Kinetics , 2013, Molecular and Cellular Biology.
[97] W. Park,et al. Association of SOD1 and SOD2 single nucleotide polymorphisms with susceptibility to gastric cancer in a Korean population , 2013, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[98] A. Siddiqui,et al. Hepatitis C Virus Induces the Mitochondrial Translocation of Parkin and Subsequent Mitophagy , 2013, PLoS pathogens.
[99] E. Jimenez-Mateos,et al. Mitochondrial localization of the Forkhead box class O transcription factor FOXO3a in brain , 2013, Journal of neurochemistry.
[100] Shuhan Sun,et al. Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma. , 2013, Carcinogenesis.
[101] E. Kohmura,et al. MicroRNA-183 upregulates HIF-1α by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells , 2013, Journal of Neuro-Oncology.
[102] H. Colman,et al. Effective Elimination of Cancer Stem Cells By a Novel Drug Combination Strategy , 2013, Stem cells.
[103] Hui Yang,et al. IDH1 and IDH2 Mutations in Tumorigenesis: Mechanistic Insights and Clinical Perspectives , 2012, Clinical Cancer Research.
[104] Chong Kiat. Goo,et al. PTEN/Akt Signaling Controls Mitochondrial Respiratory Capacity through 4E-BP1 , 2012, PloS one.
[105] M. Marinus,et al. DNA Mismatch Repair , 2012, EcoSal Plus.
[106] Rosario Rizzuto,et al. Mitochondria as sensors and regulators of calcium signalling , 2012, Nature Reviews Molecular Cell Biology.
[107] M. Honda,et al. Heterogeneous nuclear ribonucleoprotein A2/B1 in association with hTERT is a potential biomarker for hepatocellular carcinoma , 2012, Liver international : official journal of the International Association for the Study of the Liver.
[108] M. Muñoz,et al. DNA Damage-induced Heterogeneous Nuclear Ribonucleoprotein K SUMOylation Regulates p53 Transcriptional Activation* , 2012, The Journal of Biological Chemistry.
[109] S. Fuqua,et al. Tamoxifen Regulates Cell Fate Through Mitochondrial Estrogen Receptor Beta in Breast Cancer , 2012, Oncogene.
[110] H. Harada,et al. Glucocorticoid-mediated BIM induction and apoptosis are regulated by Runx2 and c-Jun in leukemia cells , 2012, Cell Death and Disease.
[111] R. Rizzuto,et al. The mitochondrial Ca(2+) uniporter. , 2012, Cell calcium.
[112] Hui Gao,et al. Erlotinib in patients with advanced non-small-cell lung cancer: A meta-analysis. , 2012, Translational lung cancer research.
[113] R. Kim,et al. To give or not to give anti-epidermal growth factor receptor (EGFR) monoclonal antibodies to patients with KRAS G13D mutation in advanced colorectal cancer. , 2012, Clinical colorectal cancer.
[114] A. Kriete,et al. The Yeast Retrograde Response as a Model of Intracellular Signaling of Mitochondrial Dysfunction , 2012, Front. Physio..
[115] N. Lindor,et al. RECQL4 is essential for the transport of p53 to mitochondria in normal human cells in the absence of exogenous stress , 2012, Journal of Cell Science.
[116] J. Neuzil,et al. Clinical significance of circulating miR-126 quantification in malignant mesothelioma patients. , 2012, Clinical biochemistry.
[117] J. Hampe,et al. Polymorphisms in the mitochondrial oxidative phosphorylation chain genes as prognostic markers for colorectal cancer , 2012, BMC Medical Genetics.
[118] Gerald C. Chu,et al. Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism , 2012, Cell.
[119] Keshav K. Singh,et al. Mitochondrial regulation of epigenetics and its role in human diseases , 2012, Epigenetics.
[120] J. Cuezva,et al. The mitochondrial ATPase inhibitory factor 1 triggers a ROS-mediated retrograde prosurvival and proliferative response. , 2012, Molecular cell.
[121] S. Berger,et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation , 2012, Nature.
[122] J. Manley,et al. Concentration-dependent control of pyruvate kinase M mutually exclusive splicing by hnRNP proteins , 2012, Nature Structural &Molecular Biology.
[123] Pui-Yan Kwok,et al. Mitochondrial DNA sequence variation and risk of pancreatic cancer. , 2012, Cancer research.
[124] E. Li,et al. MiR‐142‐3p as a potential prognostic biomarker for esophageal squamous cell carcinoma , 2012, Journal of surgical oncology.
[125] Warren Davis,et al. CAG Repeat Variants in the POLG1 Gene Encoding mtDNA Polymerase-Gamma and Risk of Breast Cancer in African-American Women , 2012, PloS one.
[126] L. Pannell,et al. Receptor Tyrosine Kinase ErbB2 Translocates into Mitochondria and Regulates Cellular Metabolism , 2012, Nature Communications.
[127] Giuseppe Longo,et al. The Inert vs. the Living State of Matter: Extended Criticality, Time Geometry, Anti-Entropy – An Overview , 2011, Front. Physio..
[128] Yidong Bai,et al. Mitochondrial respiratory complex I dysfunction promotes tumorigenesis through ROS alteration and AKT activation. , 2011, Human molecular genetics.
[129] C. Gustafsson,et al. Role of Human DNA Glycosylase Nei-like 2 (NEIL2) and Single Strand Break Repair Protein Polynucleotide Kinase 3′-Phosphatase in Maintenance of Mitochondrial Genome* , 2011, The Journal of Biological Chemistry.
[130] W. D. De Vos,et al. Repetitive disruptions of the nuclear envelope invoke temporary loss of cellular compartmentalization in laminopathies. , 2011, Human molecular genetics.
[131] D. Bar-Sagi,et al. RAS oncogenes: weaving a tumorigenic web , 2011, Nature Reviews Cancer.
[132] A. Psarra,et al. Glucocorticoids induce mitochondrial gene transcription in HepG2 cells: role of the mitochondrial glucocorticoid receptor. , 2011, Biochimica et biophysica acta.
[133] S. Hanein,et al. Mitochondria as Novel Players of the Cellular RNA Interference , 2011, The Journal of Biological Chemistry.
[134] Min Zhu,et al. Integrated miRNA and mRNA expression profiling of mouse mammary tumor models identifies miRNA signatures associated with mammary tumor lineage , 2011, Genome Biology.
[135] Russell S. Thomas,et al. The aryl hydrocarbon receptor interacts with ATP5α1, a subunit of the ATP synthase complex, and modulates mitochondrial function. , 2011, Toxicology and applied pharmacology.
[136] J. Auwerx,et al. Calorie restriction: is AMPK a key sensor and effector? , 2011, Physiology.
[137] J. Duszyński,et al. NARP mutation and mtDNA depletion trigger mitochondrial biogenesis which can be modulated by selenite supplementation. , 2011, The international journal of biochemistry & cell biology.
[138] J. Martinou,et al. Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics. , 2011, Developmental cell.
[139] I. Mills,et al. Novel Role of Androgens in Mitochondrial Fission and Apoptosis , 2011, Molecular Cancer Research.
[140] S. Amundson,et al. Radiation response and regulation of apoptosis induced by a combination of TRAIL and CHX in cells lacking mitochondrial DNA: a role for NF-κB-STAT3-directed gene expression. , 2011, Experimental cell research.
[141] S. Yamada,et al. A functional polymorphism in the epidermal growth factor gene is associated with risk for hepatocellular carcinoma. , 2011, Gastroenterology.
[142] A. Lapucci,et al. Poly(ADP-ribose) Polymerase-1 Is a Nuclear Epigenetic Regulator of Mitochondrial DNA Repair and Transcription , 2011, Molecular Pharmacology.
[143] X. Gidrol,et al. Pre-microRNA and Mature microRNA in Human Mitochondria , 2011, PloS one.
[144] Robert W Sobol,et al. Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage. , 2011, Antioxidants & redox signaling.
[145] B. Tudek,et al. 8-Oxoguanine incision activity is impaired in lung tissues of NSCLC patients with the polymorphism of OGG1 and XRCC1 genes. , 2011, Mutation research.
[146] L. Papa,et al. Estrogen receptor mediates a distinct mitochondrial unfolded protein response , 2011, Journal of Cell Science.
[147] R. Klose,et al. The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases , 2011, EMBO reports.
[148] Nicholas B. Griner,et al. Mitochondrial Dysfunction Impairs Tumor Suppressor p53 Expression/Function* , 2011, The Journal of Biological Chemistry.
[149] David M. Wilson,et al. Aprataxin localizes to mitochondria and preserves mitochondrial function , 2011, Proceedings of the National Academy of Sciences.
[150] Dongchon Kang,et al. Frequent truncating mutation of TFAM induces mitochondrial DNA depletion and apoptotic resistance in microsatellite-unstable colorectal cancer. , 2011, Cancer research.
[151] M. Murphy,et al. Wild-type and mutant p53 proteins interact with mitochondrial caspase-3 , 2011, Cancer Biology & Therapy.
[152] L. Rasmussen,et al. The Importance of Mitochondrial DNA in Aging and Cancer , 2011, Journal of aging research.
[153] W. Ruan,et al. Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies , 2011, Breast Cancer Research and Treatment.
[154] L. Burzio,et al. Nuclear localization of the mitochondrial ncRNAs in normal and cancer cells , 2011, Cellular Oncology.
[155] Shirley M. Taylor,et al. DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria , 2011, Proceedings of the National Academy of Sciences.
[156] I. Majsterek,et al. MUTYH Tyr165Cys, OGG1 Ser326Cys and XPD Lys751Gln polymorphisms and head neck cancer susceptibility: a case control study , 2011, Molecular Biology Reports.
[157] V. Schreiber,et al. Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression , 2011, Proceedings of the National Academy of Sciences.
[158] C. Distelhorst,et al. Glucocorticoid-mediated repression of the oncogenic microRNA cluster miR-17~92 contributes to the induction of Bim and initiation of apoptosis. , 2011, Molecular endocrinology.
[159] Jing He,et al. The mitochondrial DNA 4,977-bp deletion and its implication in copy number alteration in colorectal cancer , 2011, BMC Medical Genetics.
[160] B. Reina-San-Martin,et al. PARP-3 and APLF function together to accelerate nonhomologous end-joining. , 2011, Molecular cell.
[161] M. Houshmand,et al. Analysis of mitochondrial ND1 gene in human colorectal cancer , 2011, Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences.
[162] Jiayou Zhang,et al. miR-17* Suppresses Tumorigenicity of Prostate Cancer by Inhibiting Mitochondrial Antioxidant Enzymes , 2010, PloS one.
[163] C. Antonescu,et al. Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations , 2010, Proceedings of the National Academy of Sciences.
[164] T. Paull,et al. ATM activation in the presence of oxidative stress , 2010, Cell cycle.
[165] Jianbo Wu,et al. Synergistic apoptosis induction in leukemic cells by miR-15a/16-1 and arsenic trioxide. , 2010, Biochemical and biophysical research communications.
[166] J. Lubiński,et al. Mitochondrial genotype and breast cancer predisposition. , 2010, Oncology reports.
[167] Jianfang Li,et al. miR-126 functions as a tumour suppressor in human gastric cancer. , 2010, Cancer letters.
[168] Seamus J. Martin,et al. Mitochondrial fission/fusion dynamics and apoptosis. , 2010, Mitochondrion.
[169] Kyung-Han Lee,et al. 17β-Estradiol Augments 18F-FDG Uptake and Glycolysis of T47D Breast Cancer Cells via Membrane-Initiated Rapid PI3K–Akt Activation , 2010, The Journal of Nuclear Medicine.
[170] G. Hajnóczky,et al. Calcium Signalling: Fishing Out Molecules of Mitochondrial Calcium Transport , 2010, Current Biology.
[171] M. Birnbaum,et al. Activation of Akt Is Essential for the Propagation of Mitochondrial Respiratory Stress Signaling and Activation of the Transcriptional Coactivator Heterogeneous Ribonucleoprotein A2 , 2010, Molecular biology of the cell.
[172] Nicholas Bertos,et al. miR-378(∗) mediates metabolic shift in breast cancer cells via the PGC-1β/ERRγ transcriptional pathway. , 2010, Cell metabolism.
[173] C. Liou,et al. Association between a common mitochondrial DNA D-loop polycytosine variant and alteration of mitochondrial copy number in human peripheral blood cells , 2010, Journal of Medical Genetics.
[174] S. Yagi,et al. DNA methylation status of nuclear-encoded mitochondrial genes underlies the tissue-dependent mitochondrial functions , 2010, BMC Genomics.
[175] Manuela Zucknick,et al. IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[176] J. Auwerx,et al. AMP-activated protein kinase and its downstream transcriptional pathways , 2010, Cellular and Molecular Life Sciences.
[177] C. Blackstone,et al. Dynamic regulation of mitochondrial fission through modification of the dynamin‐related protein Drp1 , 2010, Annals of the New York Academy of Sciences.
[178] Junjie Chen,et al. Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha. , 2010, Molecular cell.
[179] P. Chumakov,et al. Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway , 2010, Proceedings of the National Academy of Sciences.
[180] Guanghai Yang,et al. MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC). , 2010, Clinica chimica acta; international journal of clinical chemistry.
[181] K. Vousden. Alternative fuel—another role for p53 in the regulation of metabolism , 2010, Proceedings of the National Academy of Sciences.
[182] N. Ruderman,et al. AMPK and SIRT1: a long-standing partnership? , 2010, American journal of physiology. Endocrinology and metabolism.
[183] R. Morimoto,et al. Peptides signal mitochondrial stress. , 2010, Cell metabolism.
[184] E. Shaulian,et al. Fumarase: A Mitochondrial Metabolic Enzyme and a Cytosolic/Nuclear Component of the DNA Damage Response , 2010, PLoS biology.
[185] W. Martin,et al. Molecular Poltergeists: Mitochondrial DNA Copies (numts) in Sequenced Nuclear Genomes , 2010, PLoS genetics.
[186] M. Assanah,et al. HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer , 2010, Nature.
[187] Jincheng Li,et al. miR-30 Regulates Mitochondrial Fission through Targeting p53 and the Dynamin-Related Protein-1 Pathway , 2010, PLoS genetics.
[188] M. Torbenson,et al. Mitochondrial Mutations in Hepatocellular Carcinomas and Fibrolamellar Carcinomas , 2009, Modern Pathology.
[189] Virgil L. Woods,et al. A conserved MutS homolog connector domain interface interacts with MutL homologs , 2009, Proceedings of the National Academy of Sciences.
[190] J. Sznajder,et al. Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxia-inducible factor 1. , 2009, American journal of physiology. Lung cellular and molecular physiology.
[191] Keshav K. Singh,et al. mtDNA G10398A variant in African-American women with breast cancer provides resistance to apoptosis and promotes metastasis in mice , 2009, Journal of Human Genetics.
[192] E. Jungheim,et al. Progesterone stimulates mitochondrial activity with subsequent inhibition of apoptosis in MCF-10A benign breast epithelial cells. , 2009, American journal of physiology. Endocrinology and metabolism.
[193] R. Wilson,et al. Cancer genome sequencing: a review. , 2009, Human molecular genetics.
[194] Mikhail F Alexeyev,et al. Is there more to aging than mitochondrial DNA and reactive oxygen species? , 2009, The FEBS journal.
[195] M. Rossi,et al. Mitochondrial Localization of PARP-1 Requires Interaction with Mitofilin and Is Involved in the Maintenance of Mitochondrial DNA Integrity* , 2009, The Journal of Biological Chemistry.
[196] M. Guha,et al. Heterogeneous nuclear ribonucleoprotein A2 is a common transcriptional coactivator in the nuclear transcription response to mitochondrial respiratory stress. , 2009, Molecular biology of the cell.
[197] Forest M White,et al. Oncogenic EGFR Signaling Networks in Glioma , 2009, Science Signaling.
[198] A. Gazdar,et al. Activating and resistance mutations of EGFR in non-small-cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors , 2009, Oncogene.
[199] Keshav K. Singh,et al. Cancer cell mitochondria confer apoptosis resistance and promote metastasis , 2009, Cancer biology & therapy.
[200] Keshav K. Singh,et al. Mutations in mitochondrial DNA polymerase γ promote breast tumorigenesis , 2009, Journal of Human Genetics.
[201] J. Douglas,et al. Sequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American men , 2009, The Prostate.
[202] L. Rasmussen,et al. Novel DNA mismatch-repair activity involving YB-1 in human mitochondria. , 2009, DNA repair.
[203] Keshav K. Singh,et al. p53 regulates mtDNA copy number and mitocheckpoint pathway , 2009, Journal of carcinogenesis.
[204] Johan Auwerx,et al. PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure , 2009, Current opinion in lipidology.
[205] N. Venediktova,et al. Oxidative stress induces degradation of mitochondrial DNA , 2009, Nucleic acids research.
[206] J. Bielas,et al. Quantification of random mutations in the mitochondrial genome. , 2008, Methods.
[207] N. Rothman,et al. A prospective study of mitochondrial DNA copy number and risk of non-Hodgkin lymphoma. , 2008, Blood.
[208] J. Hacia,et al. mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft , 2008, BMC Genomics.
[209] H. Leffers,et al. Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer. , 2008, Annals of oncology : official journal of the European Society for Medical Oncology.
[210] Keshav K. Singh,et al. Tumorigenic transformation of human breast epithelial cells induced by mitochondrial DNA depletion , 2008, Cancer biology & therapy.
[211] S. Covo,et al. Numt-Mediated Double-Strand Break Repair Mitigates Deletions during Primate Genome Evolution , 2008, PLoS genetics.
[212] M. Bakhanashvili,et al. p53 in mitochondria enhances the accuracy of DNA synthesis , 2008, Cell Death and Differentiation.
[213] Daozhen Chen,et al. The intra-nucleus integration of mitochondrial DNA (mtDNA)in cervical mucosa cells and its relation with c-myc expression , 2008, Journal of experimental & clinical cancer research : CR.
[214] C. Ricketts,et al. Germline SDHB mutations and familial renal cell carcinoma. , 2008, Journal of the National Cancer Institute.
[215] W. Bamlet,et al. Mitochondrial Genetic Polymorphisms Do Not Predict Survival in Patients with Pancreatic Cancer , 2008, Cancer Epidemiology Biomarkers & Prevention.
[216] S. Leal,et al. Mitochondrial DNA variant interactions modify breast cancer risk , 2008, Journal of Human Genetics.
[217] M. Spitz,et al. Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma. , 2008, Journal of the National Cancer Institute.
[218] T. Kelly,et al. Progressive tumor features accompany epithelial–mesenchymal transition induced in mitochondrial DNA–depleted cells , 2008, Cancer science.
[219] Keith W. Caldecott,et al. Single-strand break repair and genetic disease , 2008, Nature Reviews Genetics.
[220] H. Brown-Borg,et al. Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells , 2008, Neuroscience Letters.
[221] Wei Zhang,et al. The hOGG1 Ser326Cys Polymorphism and Lung Cancer Risk: A Meta-analysis , 2008, Cancer Epidemiology Biomarkers & Prevention.
[222] I. Blair,et al. DNA Adducts with Lipid Peroxidation Products* , 2008, Journal of Biological Chemistry.
[223] N. Sondheimer,et al. A Distinctive Physiological Role for IκBβ in the Propagation of Mitochondrial Respiratory Stress Signaling* , 2008, Journal of Biological Chemistry.
[224] J. Hayashi,et al. ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis , 2008, Science.
[225] Xuejun Jiang,et al. Mitochondrially localized EGFR is subjected to autophagic regulation and implicated in cell survival , 2008, Autophagy.
[226] N. Avadhani,et al. Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain* , 2008, Journal of Biological Chemistry.
[227] D. Peeper,et al. Cellular senescence in vivo: a barrier to tumorigenesis. , 2008, Current opinion in cell biology.
[228] Ru Wei,et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth , 2008, Nature.
[229] C. Klinge,et al. Estradiol stimulates transcription of nuclear respiratory factor-1 and increases mitochondrial biogenesis. , 2008, Molecular endocrinology.
[230] E. Siegel,et al. Increased distributional variance of mitochondrial DNA content associated with prostate cancer cells as compared with normal prostate cells , 2008, The Prostate.
[231] C. Haiman,et al. Mitochondrial DNA G10398A variant is not associated with breast cancer in African-American women. , 2008, Cancer genetics and cytogenetics.
[232] Y. Furuta,et al. Increased mitochondrial DNA induces acquired docetaxel resistance in head and neck cancer cells , 2008, Oncogene.
[233] J. Benítez,et al. Is mitochondrial DNA variation associated with sporadic breast cancer risk? , 2008, Cancer research.
[234] C. Moraes,et al. Transcriptional co-expression and co-regulation of genes coding for components of the oxidative phosphorylation system , 2008, BMC Genomics.
[235] I. Weissman,et al. BCL-2 and mutant NRAS interact physically and functionally in a mouse model of progressive myelodysplasia. , 2007, Cancer research.
[236] J. Russo,et al. ERbeta shifts from mitochondria to nucleus during estrogen-induced neoplastic transformation of human breast epithelial cells and is involved in estrogen-induced synthesis of mitochondrial respiratory chain proteins. , 2007, Biochimica et biophysica acta.
[237] T. Mizumachi,et al. Induction of acquired resistance to antiestrogen by reversible mitochondrial DNA depletion in breast cancer cell line , 2007, International journal of cancer.
[238] Hui Li,et al. mtDNA evidence: genetic background associated with related populations at high risk for esophageal cancer between Chaoshan and Taihang Mountain areas in China. , 2007, Genomics.
[239] M. Verma,et al. Application of mitochondrial genome information in cancer epidemiology. , 2007, Clinica chimica acta; international journal of clinical chemistry.
[240] K. Ghoshal,et al. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. , 2007, Gastroenterology.
[241] B. Spiegelman,et al. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α , 2007, Proceedings of the National Academy of Sciences.
[242] U. Moll,et al. The Role of Ubiquitination in the Direct Mitochondrial Death Program of p53 , 2007, Cell cycle.
[243] W. Bamlet,et al. Mitochondrial Genetic Polymorphisms and Pancreatic Cancer Risk , 2007, Cancer Epidemiology Biomarkers & Prevention.
[244] Michael T Ryan,et al. Mitochondrial-nuclear communications. , 2007, Annual review of biochemistry.
[245] G. Stamp,et al. Binding of Ras to Phosphoinositide 3-Kinase p110α Is Required for Ras- Driven Tumorigenesis in Mice , 2007, Cell.
[246] S. Leal,et al. Mitochondrial genetic background modifies breast cancer risk. , 2007, Cancer research.
[247] Y. Akao,et al. MicroRNA-143 and -145 in colon cancer. , 2007, DNA and cell biology.
[248] S. Srinivasan,et al. Activation of a Novel Calcineurin-mediated Insulin-like Growth Factor-1 Receptor Pathway, Altered Metabolism, and Tumor Cell Invasion in Cells Subjected to Mitochondrial Respiratory Stress* , 2007, Journal of Biological Chemistry.
[249] K. Darvishi,et al. Mitochondrial DNA G10398A polymorphism imparts maternal Haplogroup N a risk for breast and esophageal cancer. , 2007, Cancer letters.
[250] U. Kees,et al. Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia. , 2007, Cancer research.
[251] Ignacio Blanco,et al. Conventional renal cancer in a patient with fumarate hydratase mutation. , 2007, Human pathology.
[252] Ziding Feng,et al. Memorial Sloan-Kettering Cancer , 2006 .
[253] G. Park,et al. SIRT1 promotes DNA repair activity and deacetylation of Ku70 , 2007, Experimental & Molecular Medicine.
[254] E. Espinosa,et al. Phospholipid Hydroperoxide Glutathione Peroxidase (PHGPx) expression is downregulated in poorly differentiated breast invasive ductal carcinoma , 2007, Free radical research.
[255] Peng Huang,et al. Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism , 2006, The Journal of cell biology.
[256] D. Thal,et al. Incorporation and Replication of 8-Oxo-deoxyguanosine by the Human Mitochondrial DNA Polymerase* , 2006, Journal of Biological Chemistry.
[257] M. Hou,et al. A study of glutathione status in the blood and tissues of patients with breast cancer , 2006, Cell biochemistry and function.
[258] E. Bonora,et al. Novel germline variants identified in the inner mitochondrial membrane transporter TIMM44 and their role in predisposition to oncocytic thyroid carcinomas , 2006, British Journal of Cancer.
[259] P. Modrich. Mechanisms in Eukaryotic Mismatch Repair* , 2006, Journal of Biological Chemistry.
[260] A. Cheung,et al. Association of decreased mitochondrial DNA content with ovarian cancer progression , 2006, British Journal of Cancer.
[261] S. Pizzi,et al. Mitochondrial DNA D-loop in pancreatic cancer: somatic mutations are epiphenomena while the germline 16519 T variant worsens metabolism and outcome. , 2006, American journal of clinical pathology.
[262] S. Planchon,et al. Structural and functional consequences of c-N-Ras constitutively associated with intact mitochondria. , 2006, Biochimica et biophysica acta.
[263] Jean-Claude Martinou,et al. Nitric oxide‐induced mitochondrial fission is regulated by dynamin‐related GTPases in neurons , 2006, The EMBO journal.
[264] Saroj P. Mathupala,et al. Hexokinase II: Cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria , 2006, Oncogene.
[265] Marty C. Brandon,et al. Mitochondrial mutations in cancer , 2006, Oncogene.
[266] D. Reich,et al. Principal components analysis corrects for stratification in genome-wide association studies , 2006, Nature Genetics.
[267] Eyal Gottlieb,et al. TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis , 2006, Cell.
[268] A. Citri,et al. EGF–ERBB signalling: towards the systems level , 2006, Nature Reviews Molecular Cell Biology.
[269] Oksana Gavrilova,et al. p53 Regulates Mitochondrial Respiration , 2006, Science.
[270] E. Bonora,et al. Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III. , 2006, Cancer research.
[271] Muller Fabbri,et al. MicroRNAs and leukemias: how strong is the connection? , 2006, Leukemia research.
[272] Ivan H. Still,et al. Proteomic analysis of proteins involved in mitochondria-to-nucleus retrograde response in human cancer cells , 2006 .
[273] G. Cohen,et al. p53 Is Cleaved by Caspases Generating Fragments Localizing to Mitochondria* , 2006, Journal of Biological Chemistry.
[274] R. Rizzuto,et al. Mitochondrial dynamics and Ca2+ signaling. , 2006, Biochimica et biophysica acta.
[275] Keshav K. Singh. Mitochondria Damage Checkpoint, Aging, and Cancer , 2006, Annals of the New York Academy of Sciences.
[276] S. Mitra,et al. Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells , 2006, Nucleic acids research.
[277] A. Gotoh,et al. Mitochondrial DNA determines androgen dependence in prostate cancer cell lines , 2006, Oncogene.
[278] C. Thompson,et al. PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis. , 2006, Molecular cell.
[279] F. Marshall,et al. North American white mitochondrial haplogroups in prostate and renal cancer. , 2006, The Journal of urology.
[280] M. Hung,et al. EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization , 2006, Breast Cancer Research and Treatment.
[281] X. Chen,et al. Mitochondrial Aβ: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease , 2005 .
[282] A. Psarra,et al. Estrogen receptors (cid:2) and (cid:3) (ER (cid:2) and ER (cid:3) ) and androgen receptor (AR) in human sperm: localization of ER (cid:3) and AR in mitochondria of the midpiece , 2005 .
[283] J. Cidlowski,et al. Antiinflammatory action of glucocorticoids--new mechanisms for old drugs. , 2005, The New England journal of medicine.
[284] Keshav K. Singh,et al. Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors , 2005, Cancer biology & therapy.
[285] S. Sukumar,et al. Tumor‐specific changes in mtDNA content in human cancer , 2005, International journal of cancer.
[286] G. Achanta,et al. Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol γ , 2005, The EMBO journal.
[287] Izumi Horikawa,et al. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. , 2005, Molecular biology of the cell.
[288] C. Chi,et al. Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer , 2005, Genes, chromosomes & cancer.
[289] R. Millikan,et al. Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. , 2005, Cancer research.
[290] C. Chi,et al. Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer , 2005, Genes, chromosomes & cancer.
[291] Joseph Geradts,et al. Inter-genomic cross talk between mitochondria and the nucleus plays an important role in tumorigenesis. , 2005, Gene.
[292] T. D. Pugh,et al. Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging , 2005, Science.
[293] A. Cheung,et al. The increase of mitochondrial DNA content in endometrial adenocarcinoma cells: a quantitative study using laser-captured microdissected tissues. , 2005, Gynecologic oncology.
[294] T. Mourier. Reverse transcription in genome evolution , 2005, Cytogenetic and Genome Research.
[295] A. Chatterjee,et al. Oxidized guanine lesions and hOgg1 activity in lung cancer , 2005, Oncogene.
[296] S. Rhee,et al. Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling. , 2005, Free radical biology & medicine.
[297] M. Nakao,et al. Transcriptional Blockade Induces p53-dependent Apoptosis Associated with Translocation of p53 to Mitochondria* , 2005, Journal of Biological Chemistry.
[298] Pen-Hui Yin,et al. Mitochondrial Genome Instability and mtDNA Depletion in Human Cancers , 2005, Annals of the New York Academy of Sciences.
[299] N. Colburn,et al. p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase. , 2005, Cancer research.
[300] Russell G. Jones,et al. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. , 2005, Molecular cell.
[301] A. Carvalho,et al. Increased Mitochondrial DNA Content in Saliva Associated with Head and Neck Cancer , 2005, Clinical Cancer Research.
[302] Rachel Schiff,et al. Estrogen-receptor biology: continuing progress and therapeutic implications. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[303] D. Guertin,et al. Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex , 2005, Science.
[304] Okio Hino,et al. A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis. , 2005, Cancer research.
[305] Sun Young Park,et al. Cellular aging of mitochondrial DNA-depleted cells. , 2004, Biochemical and biophysical research communications.
[306] K. Roemer,et al. Identification of a putative p53 binding sequence within the human mitochondrial genome , 2004, FEBS letters.
[307] M. Wozniak,et al. Fast perinuclear clustering of mitochondria in oxidatively stressed human choriocarcinoma cells. , 2004, Folia morphologica.
[308] Keshav K. Singh. Mitochondria damage checkpoint in apoptosis and genome stability. , 2004, FEMS yeast research.
[309] E. Azzam,et al. Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: A unifying concept in stress response biology , 2004, Cancer and Metastasis Reviews.
[310] Myriam Gorospe,et al. Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase , 2004, Science.
[311] R. Kofler,et al. Glucocorticoid-induced apoptosis and glucocorticoid resistance: molecular mechanisms and clinical relevance , 2004, Cell Death and Differentiation.
[312] J. Yager,et al. Mitochondrial localization of ER and ER in human MCF7 cells , 2004 .
[313] Howard T. Jacobs,et al. Premature ageing in mice expressing defective mitochondrial DNA polymerase , 2004, Nature.
[314] N. Larebeke,et al. Endogenous DNA damage in humans: a review of quantitative data , 2004 .
[315] N. Avadhani,et al. Mitochondrial signaling: the retrograde response. , 2004, Molecular cell.
[316] M. Armoni,et al. The Tumor Suppressor p53 Down-Regulates Glucose Transporters GLUT1 and GLUT4 Gene Expression , 2004, Cancer Research.
[317] J. Simpkins,et al. Subcellular distribution of native estrogen receptor α and β subtypes in cultured human lens epithelial cells , 2004 .
[318] Noriyuki Fuku,et al. Mitochondrial Genome Single Nucleotide Polymorphisms and Their Phenotypes in the Japanese , 2004, Annals of the New York Academy of Sciences.
[319] S. Doglia,et al. Mitochondria in tumor cells studied by laser scanning confocal microscopy. , 2004, Journal of biomedical optics.
[320] I. Chang,et al. Resistance of Mitochondrial DNA-depleted Cells against Cell Death , 2004, Journal of Biological Chemistry.
[321] R. Jope,et al. Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3‐kinase activation , 2003, Journal of neurochemistry.
[322] Johanne Toutant,et al. Small interfering RNA-mediated reduction in heterogeneous nuclear ribonucleoparticule A1/A2 proteins induces apoptosis in human cancer cells but not in normal mortal cell lines. , 2003, Cancer research.
[323] L. Rasmussen,et al. Mitochondrial impairment is accompanied by impaired oxidative DNA repair in the nucleus. , 2003, Mutagenesis.
[324] N. Bresolin,et al. Remarkable infidelity of polymerase γA associated with mutations in POLG1 exonuclease domain , 2003, Neurology.
[325] J. Parsons,et al. Compromised Incision of Oxidized Pyrimidines in Liver Mitochondria of Mice Deficient in NTH1 and OGG1 Glycosylases* , 2003, Journal of Biological Chemistry.
[326] L. Rasmussen,et al. Mitochondria-mediated nuclear mutator phenotype in Saccharomyces cerevisiae. , 2003, Nucleic acids research.
[327] K. Horwitz,et al. Expression Profiling of Human Breast Cancers and Gene Regulation by Progesterone Receptors , 2003, Journal of Mammary Gland Biology and Neoplasia.
[328] F. Andris,et al. Reconstructing eukaryotic NAD metabolism. , 2003, BioEssays : news and reviews in molecular, cellular and developmental biology.
[329] H. Itoh,et al. P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA. , 2003, Cancer research.
[330] Keshav K. Singh,et al. Mitochondrial impairment in p53-deficient human cancer cells. , 2003, Mutagenesis.
[331] E. Cook,et al. Interethnic difference in the allelic distribution of human epidermal growth factor receptor intron 1 polymorphism. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[332] Petr Pancoska,et al. p53 has a direct apoptogenic role at the mitochondria. , 2003, Molecular cell.
[333] T. Price,et al. Cloning and expression of a novel, truncated, progesterone receptor , 2003, Molecular and Cellular Endocrinology.
[334] A. Hall,et al. Mismatch repair activity in mammalian mitochondria. , 2003, Nucleic acids research.
[335] John R. Johnson,et al. Native American mtDNA prehistory in the American Southwest. , 2003, American journal of physical anthropology.
[336] H. Kamiya. Mutagenic potentials of damaged nucleic acids produced by reactive oxygen/nitrogen species: approaches using synthetic oligonucleotides and nucleotides: survey and summary. , 2003, Nucleic acids research.
[337] Peng Huang,et al. Mitochondrial defects in cancer , 2002, Molecular Cancer.
[338] Sushant Kachhap,et al. Nuclear genes involved in mitochondria-to-nucleus communication in breast cancer cells , 2002, Molecular Cancer.
[339] G. Amuthan,et al. Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells , 2002, Oncogene.
[340] Jia Luo,et al. Induction or suppression of expression of cytochrome C oxidase subunit II by heregulin β 1 in human mammary epithelial cells is dependent on the levels of ErbB2 expression , 2002, Journal of cellular physiology.
[341] M. Woischnik,et al. Pattern of organization of human mitochondrial pseudogenes in the nuclear genome. , 2002, Genome research.
[342] S. Ingles,et al. The -9Ala/-9Val polymorphism in the mitochondrial targeting sequence of the manganese superoxide dismutase gene (MnSOD) is associated with age among Hispanics with colorectal carcinoma. , 2002, Oncology reports.
[343] V. Skulachev,et al. Mitochondria Enter the Nucleus (One Further Problem in Chronic Alcoholism) , 2001, Biochemistry (Moscow).
[344] I. Kirkinezos,et al. Reactive oxygen species and mitochondrial diseases. , 2001, Seminars in cell & developmental biology.
[345] I. Vetter,et al. The Guanine Nucleotide-Binding Switch in Three Dimensions , 2001, Science.
[346] P. Arctander,et al. The Human Genome Project reveals a continuous transfer of large mitochondrial fragments to the nucleus. , 2001, Molecular biology and evolution.
[347] E. Seeberg,et al. Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice. , 2001, Cancer research.
[348] E. Kandel,et al. Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. , 2001, Genes & development.
[349] T. Löning,et al. Progesterone Receptor Isoforms, PR-B and PR-A, in Breast Cancer: Correlations with Clinicopathologic Tumor Parameters and Expression of AP-1 Factors , 2001, Hormone Research in Paediatrics.
[350] R. Tyndale,et al. Ethnic variability in the allelic distribution of human aryl hydrocarbon receptor codon 554 and assessment of variant receptor function in vitro. , 2001, Pharmacogenetics.
[351] J. Parks,et al. Neurotoxic Aβ peptides increase oxidative stress in vivo through NMDA‐receptor and nitric‐oxide‐synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro , 2001, Journal of neurochemistry.
[352] M. McNiven,et al. Mitochondrial division: New partners in membrane pinching , 2001, Current Biology.
[353] Ulrich Müller,et al. Mutations in SDHC cause autosomal dominant paraganglioma, type 3 , 2000, Nature Genetics.
[354] V. Bohr,et al. Mitochondria, oxidative DNA damage, and aging , 2000, Journal of the American Aging Association.
[355] L. Oberley,et al. The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase. , 2000, Cancer research.
[356] N D Marchenko,et al. Death Signal-induced Localization of p53 Protein to Mitochondria , 2000, The Journal of Biological Chemistry.
[357] B. Devlin,et al. Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. , 2000, Science.
[358] C. Martínez-A,et al. Bcl-2 differentially targets K-, N-, and H-Ras to mitochondria in IL-2 supplemented or deprived cells: Implications in prevention of apoptosis , 1999, Oncogene.
[359] E. Kandel,et al. Akt/Protein Kinase B Inhibits Cell Death by Preventing the Release of Cytochrome c from Mitochondria , 1999, Molecular and Cellular Biology.
[360] Richard A. Roth,et al. Regulation of GLUT1 Gene Transcription by the Serine/Threonine Kinase Akt1* , 1999, The Journal of Biological Chemistry.
[361] B. Calabretta,et al. Activation of mitochondrial Raf-1 is involved in the antiapoptotic effects of Akt. , 1999, Cancer research.
[362] B. Freedman,et al. Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter‐organelle crosstalk , 1999, The EMBO journal.
[363] Bert Vogelstein,et al. Somatic mutations of the mitochondrial genome in human colorectal tumours , 1998, Nature Genetics.
[364] Samuel H. Wilson,et al. Identification of 5'-deoxyribose phosphate lyase activity in human DNA polymerase gamma and its role in mitochondrial base excision repair in vitro. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[365] E. Kolodny,et al. 5-Fluorocytosine-mediated apoptosis and DNA damage in glioma cells engineered to express cytosine deaminase and their enhancement with interferon , 1998, Journal of Neuro-Oncology.
[366] S. R. Datta,et al. Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery , 1997, Cell.
[367] T. Tamaya,et al. Clinical implication of expression of progesterone receptor form A and B mRNAs in secondary spreading of gynecologic cancers , 1997, The Journal of Steroid Biochemistry and Molecular Biology.
[368] D. Horne,et al. Transport ofS-Adenosylmethionine in Isolated Rat Liver Mitochondria , 1997 .
[369] J. Gustafsson,et al. The novel estrogen receptor‐β subtype: potential role in the cell‐ and promoter‐specific actions of estrogens and anti‐estrogens , 1997, FEBS letters.
[370] B. Van Houten,et al. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[371] G. Schatz. The Protein Import System of Mitochondria* , 1996, The Journal of Biological Chemistry.
[372] E. Shoubridge,et al. Mitochondrial genetics and human disease , 1996, BioEssays : news and reviews in molecular, cellular and developmental biology.
[373] J. Swenberg,et al. DNA adducts: biological markers of exposure and potential applications to risk assessment. , 1996, Mutation research.
[374] S. Riva,et al. The roles of heterogeneous nuclear ribonucleoproteins (hnRNP) in RNA metabolism , 1996, BioEssays : news and reviews in molecular, cellular and developmental biology.
[375] W. Copeland,et al. Mitochondrial DNA polymerase gamma is expressed and translated in the absence of mitochondrial DNA maintenance and replication. , 1996, Nucleic Acids Research.
[376] D. Wallace,et al. Novel mitochondrial DNA deletion found in a renal cell carcinoma , 1996, Genes, chromosomes & cancer.
[377] D. S. St. Clair,et al. Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase. , 1995, Oncogene.
[378] K. Mills,et al. Amplification of mitochondrial DNA in acute myeloid leukaemia , 1994, British journal of haematology.
[379] C. Wilson,et al. A and B forms of the androgen receptor are present in human genital skin fibroblasts. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[380] N. J. Pressman,et al. Cytometric validation of immunocytochemical observations in developing lung cancer , 1993, Diagnostic cytopathology.
[381] S. Ledoux,et al. Repair of oxidative damage within the mitochondrial DNA of RINr 38 cells. , 1993, The Journal of biological chemistry.
[382] T. Lindahl. Instability and decay of the primary structure of DNA , 1993, Nature.
[383] Ronald A. Butow,et al. RTG1 and RTG2: Two yeast genes required for a novel path of communication from mitochondria to the nucleus , 1993, Cell.
[384] V. Bohr,et al. Repair of mitochondrial DNA after various types of DNA damage in Chinese hamster ovary cells. , 1992, Carcinogenesis.
[385] G. Kovacs,et al. Mitochondrial and chromosomal DNA alterations in human chromophobe renal cell carcinomas , 1992, The Journal of pathology.
[386] J. Hayashi,et al. Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[387] D. Wallace,et al. Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNALys mutation , 1990, Cell.
[388] H. Yonekawa,et al. Maternally transmitted histocompatibility antigen of mice: A hydrophobic peptide of a mitochondrially encoded protein , 1990, Cell.
[389] J. L. Bos,et al. ras oncogenes in human cancer: a review. , 1989, Cancer research.
[390] G. Kovacs,et al. Alteration of mitochondrial DNA in human oncocytomas , 1989, Genes, chromosomes & cancer.
[391] M. Maltoni,et al. Study of the c-Ha-ras-1 locus polymorphism in an Italian population with high incidence of gastric cancer. , 1988, Molecular biology & medicine.
[392] C. Sekeris,et al. Presence of glucocorticoid responsive elements in the mitochondrial genome. , 1988, Anticancer research.
[393] T. Lindahl,et al. Nonenzymatic methylation of DNA by the intracellular methyl group donor S‐adenosyl‐L‐methionine is a potentially mutagenic reaction. , 1982, The EMBO journal.
[394] A. Rahi,et al. Tumours of the anterior uvea. II. Intranuclear cytoplasmic inclusions in malignant melanoma of the iris. , 1980, The British journal of ophthalmology.
[395] E. Friedberg,et al. The presence of nuclear and mitochondrial uracil-DNA glycosylase in extracts of human KB cells. , 1980, Nucleic acids research.
[396] M. Miyaki,et al. Strand breaks of mammalian mitochondrial DNA induced by carcinogens. , 1977, Chemico-biological interactions.
[397] D. A. Clayton,et al. The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria. , 1974, Proceedings of the National Academy of Sciences of the United States of America.
[398] M. Matsuyama,et al. Seizing mechanism and fate of intranuclear mitochondria , 1972, Experientia.
[399] G. Bloom. A NUCLEUS WITH CYTOPLASMIC FEATURES , 1967, The Journal of cell biology.
[400] B. Schofield,et al. Nuclear Mitochondria? , 1965, Science.
[401] Lukas D. Osborne,et al. HIF 1 a and HIF 2 a independently activate SRC to promote melanoma metastases , 2018 .
[402] H. Jarjanazi,et al. Association of the +331G/A progesterone receptor gene (PgR) polymorphism with risk of endometrial cancer in Caucasian women: a meta-analysis , 2014, Archives of Gynecology and Obstetrics.
[403] M. Zou,et al. AMPK: a cellular metabolic and redox sensor. A minireview. , 2014, Frontiers in bioscience.
[404] D. Malkin,et al. p53 and hereditary cancer. , 2014, Sub-cellular biochemistry.
[405] J. Chang-Claude,et al. Germline variants of base excision repair genes and breast cancer: A polymorphism in DNA polymerase gamma modifies gene expression and breast cancer risk , 2013, International journal of cancer.
[406] W. Xue,et al. Single-nucleotide polymorphisms of GPX1 and MnSOD and susceptibility to bladder cancer: a systematic review and meta-analysis , 2013, Tumor Biology.
[407] Y. Shiloh,et al. The ATM protein kinase: regulating the cellular response to genotoxic stress, and more. , 2013, Nature reviews. Molecular cell biology.
[408] W. D. Martin,et al. Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice. , 2012, The American journal of pathology.
[409] H. Jaafar,et al. Association of mitochondrial DNA 10398 polymorphism in invasive breast cancer in malay population of peninsular malaysia. , 2012, The Malaysian journal of medical sciences : MJMS.
[410] R. Lightowlers,et al. DNA repair in organelles: Pathways, organization, regulation, relevance in disease and aging. , 2011, Biochimica et biophysica acta.
[411] R. Mandal,et al. NER and BER repair gene polymorphisms in a healthy north Indian cohort and comparison with different ethnic groups worldwide. , 2010, Asian Pacific journal of cancer prevention : APJCP.
[412] A. Borowsky,et al. Aberrant activation of androgen receptor in a new neuropeptide-autocrine model of androgen-insensitive prostate cancer. , 2009, Cancer research.
[413] F. Ducray,et al. IDH1 and IDH2 mutations in gliomas. , 2009, The New England journal of medicine.
[414] Wei Zhang,et al. The hOGG 1 Ser 326 Cys Polymorphism and Lung Cancer Risk : A Meta-analysis , 2008 .
[415] L. Shkreta,et al. hnRNP proteins and splicing control. , 2007, Advances in experimental medicine and biology.
[416] M. Fukuzawa,et al. Renal cell carcinoma in a pediatric patient with an inherited mitochondrial mutation , 2005, Pediatric Surgery International.
[417] A. Psarra,et al. Estrogen receptors alpha and beta (ERalpha and ERbeta) and androgen receptor (AR) in human sperm: localization of ERbeta and AR in mitochondria of the midpiece. , 2005, Human reproduction.
[418] L. Aaltonen,et al. Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors. , 2004, The American journal of pathology.
[419] J. Yager,et al. Mitochondrial localization of ERalpha and ERbeta in human MCF7 cells. , 2004, American journal of physiology. Endocrinology and metabolism.
[420] N. Van Larebeke,et al. Endogenous DNA damage in humans: a review of quantitative data. , 2004, Mutagenesis.
[421] J. Simpkins,et al. Subcellular distribution of native estrogen receptor alpha and beta subtypes in cultured human lens epithelial cells. , 2004, Experimental eye research.
[422] P. Seibel,et al. Glucocorticoid and thyroid hormone receptors in mitochondria of animal cells. , 2003, International review of cytology.
[423] A. Holmgren,et al. Antioxidant function of thioredoxin and glutaredoxin systems. , 2000, Antioxidants & redox signaling.
[424] M. Bauer,et al. Protein translocation into mitochondria: the role of TIM complexes. , 2000, Trends in cell biology.
[425] C S Song,et al. Regulation of androgen action. , 1999, Vitamins and hormones.
[426] Keshav K. Singh. Mitochondrial DNA Mutations in Aging, Disease and Cancer , 1998, Springer Berlin Heidelberg.
[427] R. Mahalingam,et al. Selected nuclear LINE elements with mitochondrial‐DNA‐like inserts are more plentiful and mobile in tumor than in normal tissue of mouse and rat , 1998, Journal of cellular biochemistry.
[428] G. Takemura,et al. Intranuclear mitochondria in human myocardial cells. , 1997, Pathology, research and practice.
[429] A. Treston,et al. Purification and Characterization of a Protein That Permits Early Detection of Lung Cancer IDENTIFICATION OF HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-A2/B1 AS THE ANTIGEN FOR MONOCLONAL ANTIBODY 703D4* , 1996 .
[430] B. Ames. Oxidative DNA damage and aging , 1990 .