Dominant negative Bmp5 mutation reveals key role of BMPs in skeletal response to mechanical stimulation
暂无分享,去创建一个
[1] Amitabha Bandyopadhyay,et al. Genetic Analysis of the Roles of BMP2, BMP4, and BMP7 in Limb Patterning and Skeletogenesis , 2006, PLoS genetics.
[2] Jenneke Klein-Nulend,et al. A comparison of strain and fluid shear stress in stimulating bone cell responses—a computational and experimental study , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[3] S. M. Sims,et al. Estimating the sensitivity of mechanosensitive ion channels to membrane strain and tension. , 2004, Biophysical journal.
[4] H. Weinans,et al. Mechanical Control of Human Osteoblast Apoptosis and Proliferation in Relation to Differentiation , 2003, Calcified Tissue International.
[5] K. Lau,et al. Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways. , 2003, Bone.
[6] W. Van Hul,et al. Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators. , 2002, Developmental biology.
[7] R. Harland,et al. Effects of heterodimerization and proteolytic processing on Derrière and Nodal activity: implications for mesoderm induction in Xenopus. , 2002, Development.
[8] C. Lovejoy,et al. Bone Mineral Content and Density in the Humerus of Adult Myostatin-Deficient Mice , 2002, Calcified Tissue International.
[9] Yue Zhang,et al. Indian hedgehog Is an Essential Component of Mechanotransduction Complex to Stimulate Chondrocyte Proliferation* , 2001, The Journal of Biological Chemistry.
[10] T. Komori,et al. Tensile Stress Induces Bone Morphogenetic Protein 4 in Preosteoblastic and Fibroblastic Cells, Which Later Differentiate into Osteoblasts Leading to Osteogenesis in the Mouse Calvariae in Organ Culture , 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[11] A. E. El Haj,et al. Calcium‐channel activation and matrix protein upregulation in bone cells in response to mechanical strain , 2000, Journal of cellular biochemistry.
[12] H Sievänen,et al. Exercise-induced bone gain is due to enlargement in bone size without a change in volumetric bone density: a peripheral quantitative computed tomography study of the upper arms of male tennis players. , 2000, Bone.
[13] D. Kingsley,et al. Role of the mouse ank gene in control of tissue calcification and arthritis. , 2000, Science.
[14] E. McNally,et al. Dominant negative myostatin produces hypertrophy without hyperplasia in muscle , 2000, FEBS letters.
[15] D. Kingsley,et al. Efficient studies of long-distance Bmp5 gene regulation using bacterial artificial chromosomes. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[16] C. Hamanishi,et al. Pertussis toxin‐sensitive G proteins as mediators of stretch‐induced decrease in nitric‐oxide release of osteoblast‐like cells , 1999, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[17] E. Robertson,et al. Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. , 1999, Development.
[18] B. Hogan,et al. Bmp4 is required for the generation of primordial germ cells in the mouse embryo. , 1999, Genes & development.
[19] D. Constam,et al. Regulation of Bone Morphogenetic Protein Activity by Pro Domains and Proprotein Convertases , 1999, The Journal of cell biology.
[20] D. Burr,et al. Fluid shear-induced mechanical signaling in MC3T3-E1 osteoblasts requires cytoskeleton-integrin interactions. , 1998, American journal of physiology. Cell physiology.
[21] J. Robb,et al. Electrophysiological Responses of Human Bone Cells to Mechanical Stimulation: Evidence for Specific Integrin Function in Mechanotransduction , 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[22] D. Kingsley,et al. Joint patterning defects caused by single and double mutations in members of the bone morphogenetic protein (BMP) family. , 1996, Development.
[23] A. Bradley,et al. Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development. , 1996, Development.
[24] D. Kingsley,et al. The Role of BMPs and GDFs in Development of Region‐Specific Skeletal Structures a , 1996, Annals of the New York Academy of Sciences.
[25] B. Blumberg,et al. Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction. , 1995, Genes & development.
[26] N. Copeland,et al. Chromosomal localization, embryonic expression, and imprinting tests for Bmp7 on distal mouse chromosome 2. , 1995, Genomics.
[27] G. Leivseth,et al. Mechano-reception in osteoblast-like cells. , 1995, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[28] Jennifer Y. King,et al. BMP5 and the molecular, skeletal, and soft-tissue alterations in short ear mice. , 1994, Developmental biology.
[29] J A Frangos,et al. Role of G proteins in shear stress-mediated nitric oxide production by endothelial cells. , 1994, The American journal of physiology.
[30] J. Wittbrodt,et al. Disruption of mesoderm and axis formation in fish by ectopic expression of activin variants: the role of maternal activin. , 1994, Genes & development.
[31] M. Rudnicki,et al. MyoD or Myf-5 is required for the formation of skeletal muscle , 1993, Cell.
[32] D E Ingber,et al. Mechanotransduction across the cell surface and through the cytoskeleton. , 1993, Science.
[33] N. Copeland,et al. The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGFβ superfamily , 1992, Cell.
[34] D. Jones,et al. Biochemical signal transduction of mechanical strain in osteoblast-like cells. , 1991, Biomaterials.
[35] N. Takahashi,et al. Continuously applied compressive pressure induces bone resorption by a mechanism involving prostaglandin E2 synthesis , 1990, Journal of cellular physiology.
[36] J. Frangos,et al. Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production , 1990, Journal of cellular physiology.
[37] A. Banes,et al. The effects of mechanical strain on osteoblasts in vitro. , 1990, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.
[38] N. Takahashi,et al. Effect of a continuously applied compressive pressure on mouse osteoblast‐like cells (MC3T3‐E1) in vitro , 1990, Journal of cellular physiology.
[39] J. Eisman,et al. Muscle strength, physical fitness, and weight but not age predict femoral neck bone mass , 1989, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[40] A. Banes,et al. Osteoblasts increase their rate of division and align in response to cyclic, mechanical tension in vitro. , 1988, Bone and mineral.
[41] U. Zor,et al. The transduction of mechanical force into biochemical events in bone cells may involve activation of phospholipase A2 , 1988, Calcified Tissue International.
[42] J. Wolff. Concerning the interrelationship between form and function of the individual parts of the organism. By Julius Wolff, 1900. , 1988, Clinical orthopaedics and related research.
[43] Frost Hm,et al. The mechanostat: a proposed pathogenic mechanism of osteoporoses and the bone mass effects of mechanical and nonmechanical agents. , 1987 .
[44] T Hansson,et al. The Loads on the Lumbar Spine During Extreme Weight Lifting , 1987, Spine.
[45] K. Offord,et al. Relationship between bone mineral density of spine and strength of back extensors in healthy postmenopausal women. , 1986, Mayo Clinic proceedings.
[46] R. Wasnich,et al. The effect of long-distance running upon appendicular bone mineral content. , 1984, Medicine and science in sports and exercise.
[47] T. Wronski,et al. Effect of spaceflight on periosteal bone formation in rats. , 1983, The American journal of physiology.
[48] A. Huddleston,et al. Bone mass in lifetime tennis athletes. , 1980, JAMA.
[49] D A Nagel,et al. Humeral hypertrophy in response to exercise. , 1977, The Journal of bone and joint surgery. American volume.
[50] J M Vogel,et al. Effect of prolonged bed rest on bone mineral. , 1970, Metabolism: clinical and experimental.
[51] J. Brown,et al. Relation between bone mass and muscle weight. , 1970, Lancet.
[52] N. Bell,et al. The effects of muscle-building exercise on bone mineral density of the radius, spine, and hip in young men , 2007, Calcified Tissue International.
[53] J. Petit,et al. Pleiotropism of bone morphogenetic proteins: from bone induction to cementogenesis and periodontal ligament regeneration. , 2006, Journal of the International Academy of Periodontology.
[54] R. Derynck,et al. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. , 2003, Nature.
[55] N. Seidah,et al. Evidence that furin is an authentic transforming growth factor-beta1-converting enzyme. , 2001, The American journal of pathology.
[56] D. Kingsley. Genetic control of bone and joint formation. , 2001, Novartis Foundation symposium.
[57] D. Kingsley,et al. An extensive 3' regulatory region controls expression of Bmp5 in specific anatomical structures of the mouse embryo. , 1998, Genetics.
[58] H. Frost,et al. The mechanostat: a proposed pathogenic mechanism of osteoporoses and the bone mass effects of mechanical and nonmechanical agents. , 1987, Bone and mineral.
[59] W. J. Felts. In vivo implantation as a technique in skeletal biology. , 1961, International review of cytology.
[60] Margaret C. Green. A Rapid Method for Clearing and Staining Specimens for the Demonstration of Bone , 1952 .