Berberine modulates expression of mdr1 gene product and the responses of digestive track cancer cells to Paclitaxel

[1]  C. Chi,et al.  Up‐regulation of multidrug resistance transporter expression by berberine in human and murine hepatoma cells , 1999, Cancer.

[2]  C. Chi,et al.  Submicromolar paclitaxel induces apoptosis in human gastric cancer cells at early G1 phase. , 1998, Anticancer research.

[3]  J. Whang‐Peng,et al.  Phase II and pharmacokinetic study of paclitaxel therapy for unresectable hepatocellular carcinoma patients. , 1998, British Journal of Cancer.

[4]  F. Vikhanskaya,et al.  Inactivation of p53 in a human ovarian cancer cell line increases the sensitivity to paclitaxel by inducing G2/M arrest and apoptosis. , 1998, Experimental cell research.

[5]  C. Belani.  Paclitaxel/carboplatin in the treatment of non-small-cell lung cancer. , 1998, Oncology.

[6]  M. Kool,et al.  Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. , 1997, Cancer research.

[7]  C. Franceschi,et al.  JC‐1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess ΔΨ changes in intact cells: implications for studies on mitochondrial functionality during apoptosis , 1997, FEBS letters.

[8]  J. Petriz,et al.  Flow cytometric analysis of P-glycoprotein function using rhodamine 123 , 1997, Leukemia.

[9]  R. Kerbel,et al.  Abrogation of taxol-induced G2-M arrest and apoptosis in human ovarian cancer cells grown as multicellular tumor spheroids. , 1997, Cancer research.

[10]  Bnf.  ▼Paclitaxel and ▼docetaxel in breast and ovarian cancer , 1997, Drug and therapeutics bulletin.

[11]  L. Peters,et al.  Relationship of mitotic arrest and apoptosis to antitumor effect of paclitaxel. , 1996, Journal of the National Cancer Institute.

[12]  K. Adachi,et al.  Schedule-dependent interaction between paclitaxel and 5-fluorouracil in human carcinoma cell lines in vitro. , 1996, British Journal of Cancer.

[13]  T. Chambers,et al.  Expression, subcellular distribution and response to phorbol esters of protein kinase C (PKC) isozymes in drug-sensitive and multidrug-resistant KB cells evidence for altered regulation of PKC-alpha. , 1996, European journal of biochemistry.

[14]  L. Goldstein.  MDR1 gene expression in solid tumours. , 1996, European journal of cancer.

[15]  B. Sikic,et al.  Resistance mechanisms in human sarcoma mutants derived by single-step exposure to paclitaxel (Taxol). , 1996, Cancer research.

[16]  Y. Miura,et al.  Schedule-dependent interaction between paclitaxel and doxorubicin in human cancer cell lines in vitro. , 1995, European journal of cancer.

[17]  S. Strom,et al.  Induction of P‐Glycorprotein mRNA by protein synthesis inhibition is not controlled by a transcriptional repressor protein in rat and human liver cells , 1995 .

[18]  B. Yung,et al.  Berberine complexes with DNA in the berberine-induced apoptosis in human leukemic HL-60 cells. , 1995, Cancer letters.

[19]  E. Lazarides,et al.  Taxol-Induced Mitotic Block Triggers Rapid Onset of a p53-Independent Apoptotic Pathway , 1995, Molecular medicine.

[20]  N. Davidson.  Paclitaxel , 1995, The Lancet.

[21]  S. Ishida,et al.  Aggregation of DNA enhanced by the protoberberine alkaloids, coralyne and berberine. , 1994, Chemical & pharmaceutical bulletin.

[22]  S. Hahn,et al.  Glutathione depletion by L-buthionine sulfoximine antagonizes taxol cytotoxicity. , 1993, Cancer research.

[23]  S. Arbuck,et al.  Taxol: the first of the taxanes, an important new class of antitumor agents. , 1992, Seminars in oncology.

[24]  M. Spitaler,et al.  Detection of activity of P‐glycoprotein in human tumour samples using rhodamine 123 , 1992, British journal of haematology.

[25]  S. Thorgeirsson,et al.  Regulation of P-glycoprotein gene expression in hepatocyte cultures and liver cell lines by a trans-acting transcriptional repressor. , 1992, Nucleic acids research.

[26]  R. Donehower,et al.  Taxol: twenty years later, the story unfolds. , 1991, Journal of the National Cancer Institute.

[27]  D. V. Von Hoff,et al.  Taxol: a new and effective anti-cancer drug. , 1991, Anti-cancer drugs.

[28]  I. Roninson,et al.  Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells , 1991, Cell.

[29]  R. Donehower,et al.  Taxol: a novel investigational antimicrotubule agent. , 1990, Journal of the National Cancer Institute.

[30]  R. C. Chang,et al.  Characterization of two new cell lines derived from oral cavity human squamous cell carcinomas--OC1 and OC2. , 1990, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[31]  M. Grogl,et al.  Reversal of drug-resistant falciparum malaria by calcium antagonists: potential for host cell toxicity. , 1990, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[32]  E. Beachey,et al.  Influence of berberine sulfate on synthesis and expression of Pap fimbrial adhesin in uropathogenic Escherichia coli , 1988, Antimicrobial Agents and Chemotherapy.

[33]  W. Creasey.  Biochemical effects of berberine. , 1979, Biochemical pharmacology.

[34]  K. Sakakibara,et al.  Establishment of cultured cell lines derived from a human gastric carcinoma. , 1978, The Japanese journal of experimental medicine.

[35]  L. Wilson.  MICROTUBULES AS DRUG RECEPTORS: PHARMACOLOGICAL PROPERTIES OF MICROTUBULE PROTEIN * , 1975, Annals of the New York Academy of Sciences.

[36]  A. Krey,et al.  Berberine: Complex with DNA , 1969, Science.

[37]  C. Chi,et al.  Paclitaxel‐induced apoptosis in human gastric carcinoma cell lines , 1996, Cancer.

[38]  Y. Kano,et al.  In vitro schedule-dependent interaction between paclitaxel and cisplatin in human carcinoma cell lines , 1996, Cancer Chemotherapy and Pharmacology.

[39]  S. Strom,et al.  Induction of P-glycoprotein mRNA by protein synthesis inhibition is not controlled by a transcriptional repressor protein in rat and human liver cells. , 1995, Journal of cellular physiology.

[40]  S. Lipsitz,et al.  Phase II trial of taxol in patients with adenocarcinoma of the upper gastrointestinal tract (UGIT). The Eastern Cooperative Oncology group (ECOG) results. , 1995, Investigational new drugs.

[41]  Yue-Fang Chang,et al.  Flowcytometric analysis of the effect of berberine on the expression of glucocorticoid receptors in human hepatoma HepG2 cells. , 1994, Life sciences.

[42]  M. Brach,et al.  Ribozyme‐mediated cleavage of the MDR‐1 transcript restores chemosensitivity in previously resistant cancer cells , 1994, The EMBO journal.

[43]  M. Rosenblum,et al.  Laboratory studies of berberine used alone and in combination with 1,3-bis(2-chloroethyl)-1-nitrosourea to treat malignant brain tumors. , 1990, Chinese medical journal.

[44]  H. Nishino,et al.  Berberine sulfate inhibits tumor-promoting activity of teleocidin in two-stage carcinogenesis on mouse skin. , 1986, Oncology.