Combining transcriptional profiling and genetic linkage analysis to uncover gene networks operating in hematopoietic stem cells and their progeny
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[1] Marius Wernig,et al. Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency , 2008, Cell.
[2] H. Stefánsson,et al. Genetics of gene expression and its effect on disease , 2008, Nature.
[3] Marius Wernig,et al. c-Myc is dispensable for direct reprogramming of mouse fibroblasts. , 2008, Cell stem cell.
[4] George Q. Daley,et al. Reprogramming of human somatic cells to pluripotency with defined factors , 2008, Nature.
[5] Shulan Tian,et al. Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , 2007, Science.
[6] T. Ichisaka,et al. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2007, Cell.
[7] Steven B. Bradfute,et al. Hematopoietic fingerprints: an expression database of stem cells and their progeny. , 2007, Cell stem cell.
[8] L. Almasy,et al. Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes , 2007, Nature Genetics.
[9] Chad A Shaw,et al. Aging Hematopoietic Stem Cells Decline in Function and Exhibit Epigenetic Dysregulation , 2007, PLoS biology.
[10] B. Aronow,et al. The quantitative trait gene latexin influences the size of the hematopoietic stem cell population in mice , 2007, Nature Genetics.
[11] Jingyuan Fu,et al. Mapping Determinants of Gene Expression Plasticity by Genetical Genomics in C. elegans , 2006, PLoS genetics.
[12] Ligang Wu,et al. PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits , 2006, Nucleic Acids Res..
[13] L. Kruglyak,et al. Genetics of global gene expression , 2006, Nature Reviews Genetics.
[14] S. Yamanaka,et al. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.
[15] J. Zeitlinger,et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells , 2006, Nature.
[16] James A. Cuff,et al. A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells , 2006, Cell.
[17] Dan Nettleton,et al. Genetic Regulation of Gene Expression During Shoot Development in Arabidopsis , 2006, Genetics.
[18] S. Hunt,et al. Genome-Wide Associations of Gene Expression Variation in Humans , 2005, PLoS genetics.
[19] Joshua T. Burdick,et al. Mapping determinants of human gene expression by regional and genome-wide association , 2005, Nature.
[20] G. van Zant,et al. Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells. , 2005, Blood.
[21] C. Haley,et al. Genetical genomics in humans and model organisms. , 2005, Trends in genetics : TIG.
[22] J. Castle,et al. An integrative genomics approach to infer causal associations between gene expression and disease , 2005, Nature Genetics.
[23] I. Weissman,et al. Cell intrinsic alterations underlie hematopoietic stem cell aging. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[24] H. Geiger,et al. Regulation of hematopoietic stem cell aging in vivo by a distinct genetic element. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[25] E. Petretto,et al. Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease , 2005, Nature Genetics.
[26] Andrew I Su,et al. Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics' , 2005, Nature Genetics.
[27] Robert W. Williams,et al. Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function , 2005, Nature Genetics.
[28] E. Schadt,et al. Genetic inheritance of gene expression in human cell lines. , 2004, American journal of human genetics.
[29] C. Molony,et al. Genetic analysis of genome-wide variation in human gene expression , 2004, Nature.
[30] R. Sederoff,et al. Coordinated Genetic Regulation of Growth and Lignin Revealed by Quantitative Trait Locus Analysis of cDNA Microarray Data in an Interspecific Backcross of Eucalyptus1 , 2004, Plant Physiology.
[31] Lu Lu,et al. WebQTL: rapid exploratory analysis of gene expression and genetic networks for brain and behavior , 2004, Nature Neuroscience.
[32] H. Snoeck,et al. Quantitative Trait Analysis Reveals Transforming Growth Factor-β2 as a Positive Regulator of Early Hematopoietic Progenitor and Stem Cell Function , 2004, The Journal of experimental medicine.
[33] D. Bartel,et al. MicroRNAs Modulate Hematopoietic Lineage Differentiation , 2004, Science.
[34] Philip M. Long,et al. Comment on " 'Stemness': Transcriptional Profiling of Embryonic and Adult Stem Cells" and "A Stem Cell Molecular Signature" (I) , 2003, Science.
[35] A. Evsikov,et al. Comment on " 'Stemness': Transcriptional Profiling of Embryonic and Adult Stem Cells" and "A Stem Cell Molecular Signature" (II) , 2003, Science.
[36] Rachel B. Brem,et al. Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors , 2003, Nature Genetics.
[37] R. Stoughton,et al. Genetics of gene expression surveyed in maize, mouse and man , 2003, Nature.
[38] Leonard I Zon,et al. Portrait of a stem cell. , 2002, Developmental cell.
[39] D. Melton,et al. "Stemness": Transcriptional Profiling of Embryonic and Adult Stem Cells , 2002, Science.
[40] John T. Dimos,et al. A Stem Cell Molecular Signature , 2002, Science.
[41] E. Vellenga,et al. A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover. , 2002, Blood.
[42] H. Snoeck,et al. Genetically determined variation in the number of phenotypically defined hematopoietic progenitor and stem cells and in their response to early-acting cytokines. , 2002, Blood.
[43] L. Kruglyak,et al. Genetic Dissection of Transcriptional Regulation in Budding Yeast , 2002, Science.
[44] G. de Haan,et al. Age- and stage-specific regulation patterns in the hematopoietic stem cell hierarchy. , 2001, Blood.
[45] J. Nap,et al. Genetical genomics : the added value from segregation , 2001 .
[46] H. Nakauchi,et al. Age-Associated Characteristics of Murine Hematopoietic Stem Cells , 2000, The Journal of experimental medicine.
[47] D. Harrison,et al. Genetic regulation of primitive hematopoietic stem cell senescence. , 2000, Experimental hematology.
[48] D. Metcalf,et al. Identification of a genetic locus modulating splenomegaly induced by granulocyte colony-stimulating factor in mice , 2000, Leukemia.
[49] T. Baldwin,et al. Progenitor cell mobilization by granulocyte colony-stimulating factor controlled by loci on chromosomes 2 and 11. , 2000, Blood.
[50] M. Greaves,et al. Loops, Lineage, and Leukemia , 1998, Cell.
[51] G. de Haan,et al. Intrinsic and Extrinsic Control of Hemopoietic Stem Cell Numbers: Mapping of a Stem Cell Gene , 1997, The Journal of experimental medicine.
[52] C. Scott,et al. Genetic influences determining progenitor cell mobilization and leukocytosis induced by granulocyte colony-stimulating factor. , 1997, Blood.
[53] G. de Haan,et al. Mouse strain-dependent changes in frequency and proliferation of hematopoietic stem cells during aging: correlation between lifespan and cycling activity. , 1997, Blood.
[54] I. Weissman,et al. The aging of hematopoietic stem cells , 1996, Nature Medicine.
[55] M. Marín‐Padilla,et al. Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[56] R. Riblet,et al. Genetic control of the frequency of hematopoietic stem cells in mice: mapping of a candidate locus to chromosome 1 , 1996, The Journal of experimental medicine.
[57] J. Downing,et al. AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis , 1996, Cell.
[58] D. Harrison,et al. Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age. , 1989, Journal of immunology.
[59] R. Behringer,et al. Genetic control of hematopoietic kinetics revealed by analyses of allophenic mice and stem cell suicide , 1983, Cell.
[60] J. L. King,et al. Non-Darwinian evolution. , 1969, Science.
[61] J. Pacheco,et al. Suicide , 1968, Royal Institute of Philosophy Lectures.
[62] M. Kimura. Evolutionary Rate at the Molecular Level , 1968, Nature.
[63] Takashi Aoi,et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts , 2008, Nature Biotechnology.
[64] C. Larsen,et al. Immunogenetics , 2005, Genes and Immunity.
[65] Robert W. Williams,et al. A new set of BXD recombinant inbred lines from advanced intercross populations in mice , 2004, BMC Genetics.
[66] Albert-László Barabási,et al. Genetic Dissection of Transcriptional Regulation in Budding Yeast , 2002 .
[67] I. Weissman,et al. Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations. , 2001, Annual review of cell and developmental biology.
[68] G. de Haan,et al. Dynamic changes in mouse hematopoietic stem cell numbers during aging. , 1999, Blood.
[69] G. de Haan,et al. Genetic analysis of hemopoietic cell cycling in mice suggests its involvement in organismal life span. , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.