Heparin-induced thrombocytopenia and thrombosis.

[1]  W. Mäurer,et al.  Therapie des Heparin-induzierten Thrombose-Thrombozytopenie-Syndroms mit Immunglobulinen , 2008, Deutsche medizinische Wochenschrift.

[2]  B. Chong.  Heparin‐induced thrombocytopenia , 2003, British journal of haematology.

[3]  M. R. Jackson,et al.  Diagnosis of heparin-induced thrombocytopenia in the vascular surgery patient. , 1997, Surgery.

[4]  V. Hach-Wunderle,et al.  Heparin-related thrombosis despite normal platelet counts in vascular surgery. , 1997, American journal of surgery.

[5]  J. Kelton,et al.  A 14-year study of heparin-induced thrombocytopenia. , 1996, The American journal of medicine.

[6]  Maier Rv,et al.  Endothelial changes after shock and injury. , 1996 .

[7]  D. Silver,et al.  Use of enoxaparin in patients with heparin-induced thrombocytopenia syndrome. , 1996, Journal of vascular surgery.

[8]  A. Greinacher,et al.  Platelets of patients with peripheral arterial disease are hypersensitive to heparin. , 1996, Thrombosis research.

[9]  J. Amiral,et al.  Pathogenicity of IgA and/or IgM antibodies to heparin–PF4 complexes in patients with heparin‐induced thrombocytopenia , 1996, British journal of haematology.

[10]  A. Jawad,et al.  Comparison of PF4/heparin ELISA assay with the 14C-serotonin release assay in the diagnosis of heparin-induced thrombocytopenia. , 1995, American journal of clinical pathology.

[11]  J. Kelton,et al.  Diagnosis of heparin-induced thrombocytopenia. Still a journey, not yet a destination. , 1995, American journal of clinical pathology.

[12]  J. M. Osborne,et al.  On the Role of Platelet FcγRIIa Phenotype in Heparin-Induced Thrombocytopenia , 1995, Thrombosis and Haemostasis.

[13]  V. Roongta,et al.  Heparin binding to platelet factor-4. An NMR and site-directed mutagenesis study: arginine residues are crucial for binding. , 1995, The Biochemical journal.

[14]  F. Schiele,et al.  Use of recombinant hirudin as antithrombotic treatment in patients with heparin‐induced thrombocytopenia , 1995, American journal of hematology.

[15]  P. Leder,et al.  The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation , 1995, The Journal of experimental medicine.

[16]  G. Müller‐Berghaus,et al.  Recombinant hirudin as a new anticoagulant during cardiac operations instead of heparin: successful for aortic valve replacement in man. , 1995, The Journal of thoracic and cardiovascular surgery.

[17]  J. Hirsh,et al.  Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. , 1995, The New England journal of medicine.

[18]  J. Fontcuberta,et al.  Heparin-induced thrombocytopenia and heart operation: management with tedelparin. , 1995, The Annals of thoracic surgery.

[19]  D. Silver,et al.  Do patients with the heparin-induced thrombocytopenia syndrome have heparin-specific antibodies? , 1995, Journal of vascular surgery.

[20]  J. Kelton,et al.  Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia. , 1994, Blood.

[21]  G. Shorten,et al.  Management of cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia using prostaglandin E1 and aspirin. , 1994, Journal of cardiothoracic and vascular anesthesia.

[22]  A. Greinacher,et al.  Platelet response to vascular surgery--a preliminary study on the effect of aspirin and heparin. , 1994, Thrombosis research.

[23]  G. Laub,et al.  Heparinless cardiopulmonary bypass with ancrod. , 1994, The Annals of thoracic surgery.

[24]  J. Kelton,et al.  Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4. , 1994, Blood.

[25]  C. Feindel,et al.  Successful treatment of massive pulmonary embolism after coronary artery bypass grafting due to heparin-induced thrombocytopenia. , 1994, The Annals of thoracic surgery.

[26]  E. Frenkel,et al.  Thrombocytopenia. Issues in diagnosis and therapy. , 1994, The Medical clinics of North America.

[27]  A. Greinacher,et al.  Heparin-Associated Thrombocytopenia: The Effects of Various Intravenous lgG Preparations on Antibody Mediated Platelet Activation - A Possible New Indication for High Dose i.v. IgG , 1994, Thrombosis and Haemostasis.

[28]  A. Greinacher,et al.  Heparin-associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen. , 1994, Thrombosis and haemostasis.

[29]  D. Keeling,et al.  Platelet aggregation in response to four low molecular weight heparins and the heparinoid ORG 10172 in patients with heparin‐induced thrombocytopenia , 1994, British journal of haematology.

[30]  H. Magnani.  Heparin-Induced Thrombocytopenia (HIT): An Overview of 230 Patients Treated with Orgaran (Org 10172) , 1993, Thrombosis and Haemostasis.

[31]  M. J. Kikta,et al.  Can low molecular weight heparins and heparinoids be safely given to patients with heparin-induced thrombocytopenia syndrome? , 1993, Surgery.

[32]  J. Maraganore.  Thrombin, Thrombin Inhibitors, and the Arterial Thrombotic Process , 1993, Thrombosis and Haemostasis.

[33]  D. M. Rothkopf,et al.  The Effect of Ibuprofen on Microvascular Thrombosis in an Experimental Rabbit Model , 1993, Annals of plastic surgery.

[34]  B. P. Schmitt,et al.  Heparin-associated thrombocytopenia: a critical review and pooled analysis. , 1993, The American journal of the medical sciences.

[35]  B. Chong,et al.  The Clinical Usefulness of the Platelet Aggregation Test for the Diagnosis of Heparin-Induced Thrombocytopenia , 1993, Thrombosis and Haemostasis.

[36]  J. Brandt,et al.  Platelet aggregation studies for the diagnosis of heparin-induced thrombocytopenia. , 1993, American journal of clinical pathology.

[37]  B. Chong,et al.  Increased expression of platelet IgG Fc receptors in immune heparin-induced thrombocytopenia. , 1993, Blood.

[38]  G. Hempelmann,et al.  Influence of acute preoperative plasmapheresis on platelet function in cardiac surgery. , 1993, Journal of cardiothoracic and vascular anesthesia.

[39]  R. Mohr,et al.  The hemostatic effect of autologous platelet-rich plasma versus autologous whole blood after cardiac operations: is platelet separation really necessary? , 1993, The Journal of thoracic and cardiovascular surgery.

[40]  J. B. Borman,et al.  Aprotinin treatment during open heart operation in a patient with severe thrombocytopenia. , 1992, The Annals of thoracic surgery.

[41]  J. Amiral,et al.  Platelet Factor 4 Complexed to Heparin Is the Target for Antibodies Generated in Heparin-Induced Thrombocytopenia , 1992, Thrombosis and Haemostasis.

[42]  A. Greinacher,et al.  Heparin‐associated thrombocytopenia in a patient treated with polysulphated chondroitin sulphate: evidence for immunological crossreactivity between heparin and polysulphated glycosaminoglycan , 1992, British journal of haematology.

[43]  A. Greinacher,et al.  Heparin-Associated Thrombocytopenia: The Antibody Is Not Heparin Specific , 1992, Thrombosis and Haemostasis.

[44]  G. Anderson.  Insights into heparin‐induced thrombocytopenia , 1992, British journal of haematology.

[45]  J. Gockerman,et al.  Parenteral Anticoagulation with the Heparinoid Lomoparan (Org 10172) in Patients with Heparin Induced Thrombocytopenia and Thrombosis , 1992, Thrombosis and Haemostasis.

[46]  N. Melling,et al.  Platelet-leukocyte plasmapheresis attenuates the deleterious effects of cardiopulmonary bypass. , 1992, The Annals of thoracic surgery.

[47]  A. Greinacher,et al.  A Rapid and Sensitive Test for Diagnosing Heparin-Associated Thrombocytopenia , 1991, Thrombosis and Haemostasis.

[48]  P. T. Larsson,et al.  Effects of stress and beta-blockade on platelet function. , 1991, Circulation.

[49]  P. Brill-Edwards,et al.  Rapid anticoagulation using ancrod for heparin-induced thrombocytopenia. , 1991, Blood.

[50]  L. Kjellén,et al.  Heparin or Heparan Sulfate - What is the Difference? , 1991, Thrombosis and Haemostasis.

[51]  C. Kessler,et al.  Disseminated intravascular coagulation associated with Staphylococcus aureus septicemia is mediated by peptidoglycan-induced platelet aggregation. , 1991, The Journal of infectious diseases.

[52]  R. Aster,et al.  Characteristics of quinine- and quinidine-induced antibodies specific for platelet glycoproteins IIb and IIIa. , 1991, Blood.

[53]  A. Eldor,et al.  Edta‐dependent pseudothrombocytopenia: A clinical study of 18 patients and a review of the literature , 1991, American journal of hematology.

[54]  B. Murray,et al.  The use of a low molecular weight heparinoid (Org 10172) for extracorporeal procedures in patients with heparin dependent thrombocytopenia and thrombosis. , 1991, Australian and New Zealand journal of medicine.

[55]  P. Eisenberg,et al.  Role of new anticoagulants as adjunctive therapy during thrombolysis. , 1991, The American journal of cardiology.

[56]  J. George,et al.  The clinical importance of acquired abnormalities of platelet function. , 1991, The New England journal of medicine.

[57]  P. Damas,et al.  Heparin-Induced Thrombocytopenia: A Case Report , 1990, Angiology.

[58]  N. Takeyama,et al.  Platelet size and function in septic rats: changes in the adenylate pool. , 1990, The Journal of surgical research.

[59]  Y. Gruel,et al.  Fatal effect of re-exposure to heparin after previous heparin-associated thrombocytopenia and thrombosis , 1990, The Lancet.

[60]  S. Karzenski,et al.  Warfarin-Induced Skin Necrosis , 1990, Seminars in thrombosis and hemostasis.

[61]  D. Silver,et al.  Heparin-induced thrombocytopenia in patients who undergo open heart surgery. , 1990, Surgery.

[62]  G. Anderson,et al.  Signal transduction by the platelet Fc receptor. , 1990, Blood.

[63]  T. Ortel,et al.  "Heparin-free" cardiopulmonary bypass: first reported use of heparinoid (Org 10172) to provide anticoagulation for cardiopulmonary bypass. , 1990, Anesthesiology.

[64]  K. McCrae,et al.  Platelet activation induces increased Fc gamma receptor expression. , 1990, Journal of immunology.

[65]  C. Fisher,et al.  Intraoperative management of patients with heparin-induced thrombocytopenia. , 1990, The Annals of thoracic surgery.

[66]  M. Horne,et al.  The effect of molecular weight on heparin binding to platelets , 1990, British journal of haematology.

[67]  J. Kelton,et al.  Heparin and platelets. , 1990, Hematology/oncology clinics of North America.

[68]  S. Keating,et al.  Ancrod (Arvin) as an alternative to heparin anticoagulation for cardiopulmonary bypass. , 1989, Anesthesiology.

[69]  K. Mulvey,et al.  Correction of severe heparin-associated thrombocytopenia with intravenous immunoglobulin. , 1989, Annals of internal medicine.

[70]  R. J. Baird,et al.  Ancrod anticoagulation for cardiopulmonary bypass in heparin-induced thrombocytopenia and thrombosis. , 1989, The Annals of thoracic surgery.

[71]  B. Chong,et al.  Heparin‐induced thrombocytopenia: mechanism of interaction of the heparin‐dependent antibody with platelets , 1989, British journal of haematology.

[72]  J. Choay.  Structure and Activity of Heparin and Its Fragments: An Overview , 1989, Seminars in thrombosis and hemostasis.

[73]  D. Silver,et al.  Thrombocytopenia associated with heparin-coated catheters in patients with heparin-associated antiplatelet antibodies. , 1989, Archives of internal medicine.

[74]  J. Bussel.  Modulation of Fc receptor clearance and antiplatelet antibodies as a consequence of intravenous immune globulin infusion in patients with immune thrombocytopenic purpura. , 1989, The Journal of allergy and clinical immunology.

[75]  B. Chong,et al.  Heparin-induced thrombocytopenia: studies with a new low molecular weight heparinoid, Org 10172 , 1989 .

[76]  M. Gimbrone,et al.  Interaction of platelet factor four with cultured vascular endothelial cells. , 1989, Blood.

[77]  H. Hemker,et al.  The Mode of Action of Heparin in Plasma , 1988, Thrombosis and Haemostasis.

[78]  N. Starr,et al.  Heparin-associated thrombocytopenia: management of patients for open heart surgery. Case reports describing the use of iloprost. , 1988, Anesthesiology.

[79]  M. Sobel,et al.  Surgical management of heparin-associated thrombocytopenia. Strategies in the treatment of venous and arterial thromboembolism. , 1988, Journal of vascular surgery.

[80]  J. Kelton,et al.  Heparin-induced thrombocytopenia: laboratory studies. , 1988, Blood.

[81]  M. Horne.  Heparin binding to normal and abnormal platelets. , 1988, Thrombosis research.

[82]  M. Sobel,et al.  Characterization of platelet binding of heparins and other glycosaminoglycans. , 1988, Thrombosis research.

[83]  W. Bell,et al.  Heparin-associated thrombocytopenia and thrombosis. , 1988, The Journal of laboratory and clinical medicine.

[84]  P. Stanton,et al.  White clot syndrome. , 1988, Southern medical journal.

[85]  M. Steiner.  Platelet surface glycosaminoglycans are an effective shield for distinct platelet receptors. , 1987, Biochimica et biophysica acta.

[86]  C. Fisher,et al.  Prevention of heparin-induced thrombocytopenia during open heart surgery with iloprost (ZK36374). , 1987, Surgery.

[87]  J. Lowe,et al.  Management of patients with heparin-associated thrombocytopenia and thrombosis requiring cardiac surgery. , 1987, The Annals of thoracic surgery.

[88]  C. Kessler,et al.  In vitro correlation of platelet aggregation with occurrence of disseminated intravascular coagulation and subacute bacterial endocarditis. , 1987, The Journal of laboratory and clinical medicine.

[89]  S. Tannenbaum,et al.  Immune endothelial-cell injury in heparin-associated thrombocytopenia. , 1987, The New England journal of medicine.

[90]  D. Reid,et al.  Binding of quinine- and quinidine-dependent drug antibodies to platelets is mediated by the Fab domain of the immunoglobulin G and is not Fc dependent. , 1987, The Journal of clinical investigation.

[91]  P. Castaldi,et al.  Heparin‐induced thrombocytopenia: further studies of the effects of heparin‐dependent antibodies on platelets , 1986, British journal of haematology.

[92]  J. Vender,et al.  Heparin-associated thrombocytopenia: alternative managements. , 1986, Anesthesia and analgesia.

[93]  L. Greenfield,et al.  Dextran 40 reduces heparin-mediated platelet aggregation. , 1986, The Journal of surgical research.

[94]  D. Mikhailidis,et al.  Heparin‐induced platelet aggregation in anorexia nervosa and in severe peripheral vascular disease , 1985, European journal of clinical investigation.

[95]  H. Büller,et al.  A randomized blind study comparing standard heparin and a new low molecular weight heparinoid in cardiopulmonary bypass surgery in dogs. , 1985, The Journal of laboratory and clinical medicine.

[96]  J. Penner,et al.  Complications of heparin administration in normal individuals , 1985, American journal of hematology.

[97]  Y. Gruel,et al.  Treatment of Heparin-Associated Thrombocytopenia and Thrombosis with Low Molecular Weight Heparin (CY 216) , 1985, Seminars in thrombosis and hemostasis.

[98]  Long Rw.  Management of patients with heparin-induced thrombocytopenia requiring cardiopulmonary bypass. , 1985 .

[99]  E. R. Worth,et al.  Extracorporeal circulation in a patient with heparin-induced thrombocytopenia. , 1985, Anesthesiology.

[100]  G. Olinger,et al.  Cardiopulmonary bypass for patients with previously documented heparin-induced platelet aggregation. , 1984, The Journal of thoracic and cardiovascular surgery.

[101]  D. J. King,et al.  Heparin-associated thrombocytopenia. , 1984, Annals of internal medicine.

[102]  J. Kelton,et al.  Clinical usefulness of testing for a heparin-dependent platelet-aggregating factor in patients with suspected heparin-associated thrombocytopenia. , 1984, The Journal of laboratory and clinical medicine.

[103]  D. Lane,et al.  Anticoagulant activities of heparin oligosaccharides and their neutralization by platelet factor 4. , 1984, The Biochemical journal.

[104]  M. Petitou,et al.  Structure-activity relationship in heparin: a synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity. , 1983, Biochemical and biophysical research communications.

[105]  D. Silver,et al.  Heparin-induced thrombocytopenia with thrombosis and hemorrhage. , 1983, Archives of surgery.

[106]  D. Lane,et al.  Binding of platelet factor 4 to heparin oligosaccharides. , 1983, The Biochemical journal.

[107]  C. Prowse,et al.  The in vivo release of human platelet factor 4 by heparin. , 1982, Thrombosis research.

[108]  T. Bjornsson,et al.  Heparin kinetics determined by three assay methods , 1982, Clinical pharmacology and therapeutics.

[109]  C. S. Grace,et al.  Heparin‐induced Thrombocytopenia: Effect of Heparin Platelet Antibody on Platelets , 1981, British journal of haematology.

[110]  J. Holbrook,et al.  The transfer of platelet factor 4 from its proteoglycan carrier to natural and synthetic polymers. , 1981, Biochimica et biophysica acta.

[111]  A. Schreiber,et al.  Heparin-associated thrombocytopenia. , 1980, The New England journal of medicine.

[112]  D. Pepper,et al.  Binding of platelet factor 4 to cultured human umbilical vein endothelial cells. , 1980, Thrombosis research.

[113]  D. Deykin,et al.  Heparin‐induced thrombocytopenia and recurrent thromboembolism , 1980, American journal of hematology.

[114]  V. Bernhard,et al.  White clot syndrome. Peripheral vascular complications of heparin therapy. , 1979, Archives of surgery.

[115]  D. Stechschulte,et al.  Thrombocytopenia associated with antiheparin antibody. , 1978, JAMA.

[116]  D. Silver,et al.  Heparin Induced Thrombocytopenia: Eight Cases with Thrombotic‐Hemorrhagic Complications , 1977, Annals of surgery.

[117]  B. Evatt,et al.  In vitro studies of heparin-associated thrombocytopenia. , 1977, Thrombosis research.

[118]  P. Tomasulo,et al.  Thrombocytopenia occurring during the administration of heparin. A prospective study in 52 patients. , 1976, Annals of internal medicine.

[119]  R. B. Babcock,et al.  Heparin-induced immune thrombocytopenia. , 1976, The New England journal of medicine.

[120]  H. Gralnick,et al.  Heparin-induced thrombocytopenia: confirmation of diagnosis with in vitro methods. , 1975, Blood.

[121]  D. Silver,et al.  Heparin induced thrombocytopenia with thrombotic and hemorrhagic manifestations. , 1973, Surgery, gynecology & obstetrics.

[122]  E. Lüscher,et al.  Characterization of a chondroitin 4 -sulfate proteoglycan carrier for heparin neutralizing activity (platelet factor 4 ) released from human blood platelets. , 1972, Biochimica et biophysica acta.

[123]  B. Roberts,et al.  HEPARIN--A CAUSE OF ARTERIAL EMBOLI? , 1964, Surgery.

[124]  A. Ulin,et al.  Heparin-induced thrombocytopenia in man. , 1962, The Journal of laboratory and clinical medicine.

[125]  R. Weismann,et al.  Arterial embolism occurring during systemic heparin therapy. , 1958, A.M.A. archives of surgery.

[126]  Jaques Lb,et al.  The effect of commercial heparin on the platelet count. , 1948, The Journal of laboratory and clinical medicine.

[127]  J. Amiral,et al.  Antibodies to Macromolecular Platelet Factor 4-Heparin Complexes in Heparin-induced Thrombocytopenia: a Study of 44 Cases , 1995, Thrombosis and Haemostasis.

[128]  J. Scott,et al.  Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells. , 1994, The Journal of clinical investigation.

[129]  B. Chong,et al.  Orgaran in Heparin-lnduced Thrombocytopenia , 1992 .

[130]  D. Hoppensteadt,et al.  Effect of dermatan sulfate and heparan sulfate on platelet activity compared to heparin. , 1991, Seminars in thrombosis and hemostasis.

[131]  J. Hirsh.  Drug therapy : heparin , 1991 .

[132]  B. Casu,et al.  Structural features and binding properties of chondroitin sulfates, dermatan sulfate, and heparan sulfate. , 1991, Seminars in thrombosis and hemostasis.

[133]  S. Adnot,et al.  Low molecular weight heparin fractions as an alternative therapy in heparin-induced thrombocytopenia. , 1987, Haemostasis.

[134]  R. Hull,et al.  Antithrombotic therapy for venous thromboembolic disease. , 1986, Chest.

[135]  J. Kelton,et al.  A diagnostic test for heparin-induced thrombocytopenia , 1986 .

[136]  J. George,et al.  Human platelet surface binding of endogenous secreted factor VIII-von Willebrand factor and platelet factor 4 , 1982 .

[137]  R. Rosenberg,et al.  Effect of heparin and heparin fractions on platelet aggregation. , 1980, The Journal of clinical investigation.

[138]  L. Jaques,et al.  Vascular sequestration of heparin. , 1978, Thrombosis research.