Investigation into the thermal distribution of microwave helical antennas designed for the treatment of Barrett's oesophagus.

A set of helical microwave antennas was designed to investigate their potential use in thermal therapy of Barrett's oesophagus. The antennas had a diameter of up to 3.3 mm and various lengths between 20 and 37 mm; these were designed to operate at 915 MHz. Sets of polytetrafluoroethylene (PTFE) formers were constructed to improve the repeatability and reproducibility of the helix manufacture. Small diameter copper wire was wound over the formers and connected to the coaxial cable at the inner and outer conductor junctions. The power deposition profiles of the antennas were measured in a muscle-equivalent phantom using an infrared camera. The effects of antenna length and coil spacing were characterized. It was observed that uniform temperature profiles along the antenna length were achieved with a length of wire of 99 mm +/- 2 mm. The effective heating length (length of the antenna that exhibits > 50% of the maximum temperature rise) was comparable to the antenna length. The radial penetration depth of 50% of the antenna surface temperature for the optimum 20 mm antenna was 2.5 mm from the antenna outer surface.

[1]  G Hartsgrove,et al.  Simulated biological materials for electromagnetic radiation absorption studies. , 1987, Bioelectromagnetics.

[2]  J Trachtenberg,et al.  Helical antenna arrays for interstitial microwave thermal therapy for prostate cancer: tissue phantom testing and simulations for treatment. , 2001, Physics in medicine and biology.

[3]  T. Cetas,et al.  Heating pattern of helical microwave intracavitary oesophageal applicator. , 1991, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[4]  F. Ellis,et al.  Endoscopic surveillance of Barrett's esophagus. Does it help? , 1993, The Journal of thoracic and cardiovascular surgery.

[5]  T. Ryan,et al.  Comparison of six microwave antennas for hyperthermia treatment of cancer: sar results for single antennas and arrays. , 1991, International journal of radiation oncology, biology, physics.

[6]  W. Samowitz,et al.  Restoration of squamous mucosa after ablation of Barrett's esophageal epithelium. , 1993, Gastroenterology.

[7]  R. R. Smith,et al.  Prevalence and characteristics of Barrett esophagus in patients with adenocarcinoma of the esophagus or esophagogastric junction. , 1988, Human pathology.

[8]  P. Stauffer,et al.  Implantable helical coil microwave antenna for interstitial hyperthermia. , 1988, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.