Computed tomographic mammography using a conventional body scanner.

The technique for computed tomographic (CT) examination of the breasts using a conventional body scanner is described, and experience with 67 patients is reported. In the diagnosis of both malignant and benign breast lesions, the results with a body scanner were equal to those of a dedicated CT/M mammographic unit. Although the CT study of the breast cannot replace conventional mammography in screening or in routine diagnostic workup, the unique capability of demonstrating both anatomic changes and increased iodide concentration in a cancer provides many advantages over conventional mammography. CT mammography appears to have the capability to detect breast cancers that are occult to other methods. Indications for a CT study of the breasts are: (1) clinically suspected breast cancer, especially with a mammographically occult lesion; (2) questionable mammographic findings, including microcalcifications, tumor shape, architectural distortion, and uncertain lesion location; and (3) evaluation of postbiopsy or postlumpectomy breast cancers when a primary irradiation therapy is contemplated. Breast CT also appears to be a valuable diagnostic tool in searching for a second primary breast cancer, follow-up study of postirradiation of breast cancer, followup study for postmastectomy patients, and screening procedure for genetically high-risk patients, especially those with dense breasts.

[1]  J. Newhouse,et al.  Tissue distribution of soluble contrast: effect of dose variation and changes with time. , 1981, AJR. American journal of roentgenology.

[2]  R. Muir The evolution of carcinoma of the mamma , 1941 .

[3]  M. Black,et al.  Association of atypical characteristics of benign breast lesions with subsequent risk of breast cancer , 1972, Cancer.

[4]  A. W. Templeton,et al.  Computed tomography in detection and diagnosis of breast cancer , 1980, Cancer.

[5]  J. H. Gallagher,et al.  Computed tomographic evaluation of the breast. , 1978, AJR. American journal of roentgenology.

[6]  D. Page,et al.  Relation between component parts of fibrocystic disease complex and breast cancer. , 1978, Journal of the National Cancer Institute.

[7]  M. Moskowitz,et al.  Proliferative disorders of the breast as risk factors for breast cancer in a self-selected screened population: pathologic markers. , 1980, Radiology.

[8]  J. J. Gisvold,et al.  Computed tomographic mammography (CTM). , 1979, AJR. American journal of roentgenology.

[9]  J. Sibala,et al.  Computed tomographic mammography. Diagnosis of mammographically and clinically occult carcinoma of the breast. , 1981, Archives of surgery.

[10]  S J Dwyer,et al.  Specific value of computed tomographic breast scanner (CT/M) in diagnosis of breast diseases. , 1979, Radiology.

[11]  J. H. Gallagher,et al.  Computed tomography of the breast. A preliminary report. , 1977, Radiology.

[12]  A W Templeton,et al.  Preoperative diagnosis of potentially precancerous breast lesions by computed tomography breast scanner: preliminary study. , 1978, Radiology.

[13]  P. Dean,et al.  The diagnostic potential of contrast enhancement pharmacokinetics. , 1978, Investigative radiology.