The LKB 1 Tumor Suppressor as a Biomarker in Mouse and Human Tissues
暂无分享,去创建一个
D. Hayes | Kwok-Kin Wong | N. Sharpless | N. Bardeesy | D. Castrillon | N. Zhao | Song Zhang | T. Stewart | Y. Nakada | C. G. Peña | Kwok-kin Wong
[1] E. Wang,et al. Clinicopathologic Correlations of Liver Kinase B1, E-Cadherin, and N-Cadherin Expression in Non–Small Cell Lung Cancer , 2013, Applied immunohistochemistry & molecular morphology : AIMM.
[2] C. Perou,et al. LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma. , 2012, Cancer cell.
[3] Matthew D. Wilkerson,et al. Differential Pathogenesis of Lung Adenocarcinoma Subtypes Involving Sequence Mutations, Copy Number, Chromosomal Instability, and Methylation , 2012, PloS one.
[4] D. Sabatini,et al. mTOR Signaling in Growth Control and Disease , 2012, Cell.
[5] Andrew L. Kung,et al. A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response , 2012, Nature.
[6] A. Marcus,et al. Localization‐specific LKB1 loss in head and neck squamous cell carcinoma metastasis , 2011, Head & neck.
[7] T. Mäkelä,et al. Molecular mechanisms of tumor suppression by LKB1 , 2011, FEBS letters.
[8] C. Walker,et al. The role of LKB1 and AMPK in cellular responses to stress and damage , 2011, FEBS letters.
[9] Christopher R. Cabanski,et al. Lung Squamous Cell Carcinoma mRNA Expression Subtypes Are Reproducible, Clinically Important, and Correspond to Normal Cell Types , 2010, Clinical Cancer Research.
[10] M. Wilkerson,et al. Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors. , 2010, Cancer cell.
[11] Guohua Zhang,et al. Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression. , 2010, Oncology reports.
[12] Kwok-Kin Wong,et al. Lkb1 inactivation is sufficient to drive endometrial cancers that are aggressive yet highly responsive to mTOR inhibitor monotherapy , 2010, Disease Models & Mechanisms.
[13] R. Shaw,et al. The LKB1–AMPK pathway: metabolism and growth control in tumour suppression , 2009, Nature Reviews Cancer.
[14] Chin-Lee Wu,et al. mTOR and HIF-1α-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome , 2009, Proceedings of the National Academy of Sciences.
[15] Kwok-Kin Wong,et al. Somatic LKB1 Mutations Promote Cervical Cancer Progression , 2009, PloS one.
[16] A. Hezel,et al. LKB1; linking cell structure and tumor suppression , 2008, Oncogene.
[17] D. Hayes,et al. LKB1 and lung cancer: more than the usual suspects. , 2008, Cancer research.
[18] Y. Miyagi,et al. LKB1 protein expression in neuroendocrine tumors of the lung , 2008, Pathology international.
[19] Kwok-Kin Wong,et al. Loss of Lkb1 provokes highly invasive endometrial adenocarcinomas. , 2008, Cancer research.
[20] F. López-Ríos,et al. Specific pattern of LKB1 and phospho-acetyl-CoA carboxylase protein immunostaining in human normal tissues and lung carcinomas. , 2007, Human pathology.
[21] D. Neil Hayes,et al. LKB1 modulates lung cancer differentiation and metastasis , 2007, Nature.
[22] Kei Sakamoto,et al. LKB1-dependent signaling pathways. , 2006, Annual review of biochemistry.
[23] M. Rossel,et al. Stability of the Peutz–Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37 , 2003, Oncogene.
[24] P. Guldberg,et al. Somatic mutation of the Peutz-Jeghers syndrome gene, LKB1/STK11, in malignant melanoma , 1999, Oncogene.
[25] M. Stratton,et al. A serine/threonine kinase gene defective in Peutz–Jeghers syndrome , 1998, Nature.
[26] D. Anderson,et al. Generation of papillomavirus-immortalized cell lines from normal human ectocervical, endocervical, and vaginal epithelium that maintain expression of tissue-specific differentiation proteins. , 1997, Biology of reproduction.