Strategies of European SMEs in Biotechnology: The Role of Size, Technology and Market

Both the technological and market focus of 228 European biotechnology SMEs are analysed in this paper. Data from the Genetic Engineering catalogue provide a complementary representation compared to the patent publications that are most commonly used. Results of the analysis produce a new view of the development of biotech SMEs. First, no pattern of specialisation by country is observed, even though three types of company with different technological focus can be distinguished in the sample. Second, it is argued that the rapid technological evolution in this domain can hardly be explained by a rapid evolution of the technological basis of the companies, and should consequently be explained primarily by the creation of new SMEs. Third, four different patterns of linkage between technology and market focus are observed, by means of co-word analysis.

[1]  Luigi Orsenigo,et al.  The Emergence of Biotechnology: Institutions and Markets in Industrial Innovation , 1989 .

[2]  P. B. Joly,et al.  Genome patents , 1996, Nature.

[3]  Vivien Walsh,et al.  Small-firm formation in biotechnology: A comparison of France, Britain and Canada , 1995 .

[4]  M. Sharp,et al.  The science of nations: European multinationals and American biotechnology , 1999 .

[5]  Marie-Angèle de Looze,et al.  An analysis of innovation strategies and industrial differentiation through patent applications: the case of plant biotechnology , 1996 .

[6]  Luigi Orsenigo,et al.  The emergence of biotechnology , 1989 .

[7]  S. Winter,et al.  Appropriating the Returns from Industrial Research and Development , 1987 .

[8]  W. Powell,et al.  Interorganizational Collaboration and the Locus of Innovation: Networks of Learning in Biotechnology. , 1996 .

[9]  J. Niosi National systems of innovations are “x-efficient” (and x-effective): Why some are slow learners , 2002 .

[10]  Franco Malerba,et al.  Schumpeterian patterns of innovation are technology-specific , 1996 .

[11]  William J. Abernathy,et al.  Patterns of Industrial Innovation , 1978 .

[12]  Jacqueline Senker,et al.  Biotechnology and competitive advantage: Europe's firms and the US challenge , 1998 .

[13]  David B. Audretsch,et al.  Innovation in Large and Small Firms: An Empirical Analysis , 1988 .

[14]  Dominique Vinck,et al.  Gestion de la recherche : nouveaux problèmes, nouveaux outils , 1991 .

[15]  Roger Coronini,et al.  A note on recent trends in knowledge creation and appropriation through genomics: a scientometric analysis , 2001 .

[16]  Marc Humbert,et al.  The impact of globalisation on Europe's firms and industries , 1993 .

[17]  Jacqueline Senker,et al.  Organizational Learning in Cooperative Alliances: Some Case Studies in Biotechnology , 1997 .

[18]  M. Tushman,et al.  Technological Discontinuities and Dominant Designs: A Cyclical Model of Technological Change , 1990 .

[19]  Hitoo Nishino,et al.  Beyond the language barrier , 1996, Nature.

[20]  Katherine W. McCain,et al.  The structure of biotechnology R & D , 1995, Scientometrics.