Integrative Genomic Analyses Identifies GGA2 as a Cooperative Driver of EGFR‐Mediated Lung Tumorigenesis
暂无分享,去创建一个
Bradley P. Coe | B. Coe | S. Lam | W. Lam | R. Somwar | W. Lockwood | K. Thu | D. Lu | V. Martinez | Y. Inoue | L. Beverly | A. Unni | M. Oh | Victor D. Martinez | A. Nagelberg | B. Harbourne | H. O'Farrell | Zimple Kurlawala
[1] S. Waguri,et al. GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growth , 2018, Scientific Reports.
[2] S. Elledge,et al. A genetic interaction analysis identifies cancer drivers that modify EGFR dependency. , 2017, Genes & development.
[3] Wei Huang,et al. Regulation of α2B-Adrenergic Receptor Cell Surface Transport by GGA1 and GGA2 , 2016, Scientific Reports.
[4] Jaime Rodriguez-Canales,et al. An Expression Signature as an Aid to the Histologic Classification of Non–Small Cell Lung Cancer , 2016, Clinical Cancer Research.
[5] M. Ringnér,et al. Genomic and Transcriptional Alterations in Lung Adenocarcinoma in Relation to Smoking History , 2014, Clinical Cancer Research.
[6] Steven J. M. Jones,et al. Comprehensive molecular profiling of lung adenocarcinoma , 2014, Nature.
[7] D. Morris,et al. The developing story of Sprouty and cancer , 2014, Cancer and Metastasis Reviews.
[8] C. Futter,et al. EGF receptor trafficking: consequences for signaling and cancer , 2014, Trends in cell biology.
[9] S. Lam,et al. YEATS4 is a novel oncogene amplified in non-small cell lung cancer that regulates the p53 pathway. , 2013, Cancer research.
[10] Ian M. Wilson,et al. EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk , 2013, Oncogene.
[11] John D. Minna,et al. Human Lung Epithelial Cells Progressed to Malignancy through Specific Oncogenic Manipulations , 2013, Molecular Cancer Research.
[12] H. Varmus,et al. Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins , 2012, Proceedings of the National Academy of Sciences.
[13] Benjamin E. Gross,et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. , 2012, Cancer discovery.
[14] S. Lam,et al. Lung Adenocarcinoma of Never Smokers and Smokers Harbor Differential Regions of Genetic Alteration and Exhibit Different Levels of Genomic Instability , 2012, PloS one.
[15] Chris Sander,et al. Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines , 2011, Proceedings of the National Academy of Sciences.
[16] Kwon-Sik Park,et al. Lung cancer signatures in plasma based on proteome profiling of mouse tumor models. , 2011, Cancer cell.
[17] John D. Minna,et al. Divergent Genomic and Epigenomic Landscapes of Lung Cancer Subtypes Underscore the Selection of Different Oncogenic Pathways during Tumor Development , 2011, PloS one.
[18] Morag Park,et al. GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration. , 2011, Developmental cell.
[19] Yosef Yarden,et al. Feedback regulation of EGFR signalling: decision making by early and delayed loops , 2011, Nature Reviews Molecular Cell Biology.
[20] N. Girard,et al. New driver mutations in non-small-cell lung cancer. , 2011, The Lancet. Oncology.
[21] A. Iafrate,et al. Genetically informed lung cancer medicine , 2011, The Journal of pathology.
[22] B. Job,et al. Genomic Aberrations in Lung Adenocarcinoma in Never Smokers , 2010, PloS one.
[23] Hua-Chien Chen,et al. EGFR promotes lung tumorigenesis by activating miR-7 through a Ras/ERK/Myc pathway that targets the Ets2 transcriptional repressor ERF. , 2010, Cancer research.
[24] William Pao,et al. Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer , 2010, Nature Reviews Cancer.
[25] Calum MacAulay,et al. Integrative Genomic Analyses Identify BRF2 as a Novel Lineage-Specific Oncogene in Lung Squamous Cell Carcinoma , 2010, PLoS medicine.
[26] B. Coe,et al. FACADE: a fast and sensitive algorithm for the segmentation and calling of high resolution array CGH data , 2010, Nucleic acids research.
[27] John D. Minna,et al. Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy , 2010, Cancer and Metastasis Reviews.
[28] A. Charollais,et al. Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins. , 2010, Human molecular genetics.
[29] T. Mok,et al. A small step towards personalized medicine for non-small cell lung cancer. , 2009, Discovery medicine.
[30] Calum MacAulay,et al. Oncogene Mutations, Copy Number Gains and Mutant Allele Specific Imbalance (MASI) Frequently Occur Together in Tumor Cells , 2009, PloS one.
[31] Chris Sander,et al. An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors , 2009, Oncogene.
[32] Brian H. Dunford-Shore,et al. Somatic mutations affect key pathways in lung adenocarcinoma , 2008, Nature.
[33] John D. Minna,et al. Deregulated EGFR Signaling during Lung Cancer Progression: Mutations, Amplicons, and Autocrine Loops , 2008, Cancer Prevention Research.
[34] B. Coe,et al. DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers , 2008, Oncogene.
[35] Derek Y. Chiang,et al. Characterizing the cancer genome in lung adenocarcinoma , 2007, Nature.
[36] H. Varmus,et al. Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors. , 2006, Genes & development.
[37] Bradley P. Coe,et al. Differential disruption of cell cycle pathways in small cell and non-small cell lung cancer , 2006, British Journal of Cancer.
[38] J. Minna,et al. Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells. , 2006, Cancer research.
[39] Kimmo J Hatanpaa,et al. Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells. , 2006, Cancer research.
[40] R. Wilson,et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[41] S. Gabriel,et al. EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy , 2004, Science.
[42] A. D. Robertson,et al. GGA proteins bind ubiquitin to facilitate sorting at the trans-Golgi network , 2004, Nature Cell Biology.
[43] E. Ma,et al. Chromosomal aberrations of primary lung adenocarcinomas in nonsmokers , 2003, Cancer.
[44] H. Geuze,et al. Cooperation of GGAs and AP-1 in Packaging MPRs at the Trans-Golgi Network , 2002, Science.
[45] Wanpin Chang,et al. Memapsin 2 (β‐secretase) cytosolic domain binds to the VHS domains of GGA1 and GGA2: implications on the endocytosis mechanism of memapsin 2 , 2002, FEBS letters.
[46] P. Madsen,et al. The sortilin cytoplasmic tail conveys Golgi–endosome transport and binds the VHS domain of the GGA2 sorting protein , 2001, The EMBO journal.
[47] R. Tibshirani,et al. Significance analysis of microarrays applied to the ionizing radiation response , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[48] N. Hanna,et al. EGF Receptor Gene Mutations Are Common in Lung Cancers From “Never Smokers” and Are Associated With Sensitivity of Tumors to Gefitinib and Erlotinib , 2006 .
[49] J. Bonifacino. The GGA proteins: adaptors on the move , 2004, Nature Reviews Molecular Cell Biology.