The netrin protein family

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[2]  M. Sheng,et al.  Trans-synaptic adhesion between NGL-3 and LAR regulates the formation of excitatory synapses , 2009, Nature Neuroscience.

[3]  K. Klinger,et al.  Netrin-4 regulates angiogenic responses and tumor cell growth. , 2009, Experimental cell research.

[4]  Y. Rao,et al.  DSCAM functions as a netrin receptor in commissural axon pathfinding , 2009, Proceedings of the National Academy of Sciences.

[5]  G. Steinberg,et al.  Netrin-4 Enhances Angiogenesis and Neurologic Outcome after Cerebral Ischemia , 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[6]  J. Antel,et al.  Netrin 1 and Dcc regulate oligodendrocyte process branching and membrane extension via Fyn and RhoA , 2009, Development.

[7]  A. Sadikot,et al.  Graded expression of netrin-1 by specific neuronal subtypes in the adult mammalian striatum , 2008, Neuroscience.

[8]  F. Charron,et al.  Dscam guides embryonic axons by Netrin-dependent and -independent functions , 2008, Development.

[9]  J. Antel,et al.  Maintenance of Axo-Oligodendroglial Paranodal Junctions Requires DCC and Netrin-1 , 2008, The Journal of Neuroscience.

[10]  M. Poupon,et al.  Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B , 2008, Proceedings of the National Academy of Sciences.

[11]  M. Tessier-Lavigne,et al.  DSCAM Is a Netrin Receptor that Collaborates with DCC in Mediating Turning Responses to Netrin-1 , 2008, Cell.

[12]  D. Sellers,et al.  Adult spinal cord progenitor cells are repelled by netrin-1 in the embryonic and injured adult spinal cord , 2007, Proceedings of the National Academy of Sciences.

[13]  Daniel A. Colón-Ramos,et al.  Glia Promote Local Synaptogenesis Through UNC-6 (Netrin) Signaling in C. elegans , 2007, Science.

[14]  A. Afenjar,et al.  Netrin G1 mutations are an uncommon cause of atypical Rett syndrome with or without epilepsy. , 2007, Pediatric neurology.

[15]  M. Paulsson,et al.  Binding of Netrin-4 to Laminin Short Arms Regulates Basement Membrane Assembly* , 2007, Journal of Biological Chemistry.

[16]  Renping Zhou,et al.  Characterization of the receptors for axon guidance factor netrin-4 and identification of the binding domains , 2007, Molecular and Cellular Neuroscience.

[17]  T. Kennedy,et al.  When a diffusible axon guidance cue stops diffusing: roles for netrins in adhesion and morphogenesis , 2006, Current Opinion in Neurobiology.

[18]  R. Weinberg,et al.  NGL family PSD-95–interacting adhesion molecules regulate excitatory synapse formation , 2006, Nature Neuroscience.

[19]  Hao Wang,et al.  Axon Guidance by Diffusible Chemoattractants: A Gradient of Netrin Protein in the Developing Spinal Cord , 2006, The Journal of Neuroscience.

[20]  M. Tessier-Lavigne,et al.  UNC5A promotes neuronal apoptosis during spinal cord development independent of netrin-1 , 2006, Nature Neuroscience.

[21]  M. Martindale,et al.  Molecular evidence for deep evolutionary roots of bilaterality in animal development. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[22]  R. Burgess,et al.  Motor Axon Guidance of the Mammalian Trochlear and Phrenic Nerves: Dependence on the Netrin Receptor Unc5c and Modifier Loci , 2006, The Journal of Neuroscience.

[23]  A. Clarke,et al.  NTNG1 mutations are a rare cause of Rett syndrome , 2006, American journal of medical genetics. Part A.

[24]  Keisuke Ito,et al.  Netrin 1 regulates ventral tangential migration of guidepost neurons in the lateral olfactory tract , 2006, Development.

[25]  P. Mehlen,et al.  Netrin-1: when a neuronal guidance cue turns out to be a regulator of tumorigenesis , 2005, Cellular and Molecular Life Sciences.

[26]  H. Firth,et al.  Disruption of Netrin G1 by a balanced chromosome translocation in a girl with Rett syndrome , 2005, European Journal of Human Genetics.

[27]  Yi Rao,et al.  Netrin-1 and slit-2 regulate and direct neurite growth of ventral midbrain dopaminergic neurons , 2005, Molecular and Cellular Neuroscience.

[28]  C. Chien,et al.  When sugars guide axons: insights from heparan sulphate proteoglycan mutants , 2004, Nature Reviews Genetics.

[29]  K. Guan,et al.  Mapping Netrin Receptor Binding Reveals Domains of Unc5 Regulating Its Tyrosine Phosphorylation , 2004, The Journal of Neuroscience.

[30]  Dean Y. Li,et al.  The axonal attractant Netrin-1 is an angiogenic factor. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[31]  S. Itohara,et al.  Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules , 2004, The Journal of comparative neurology.

[32]  Li Yuan,et al.  The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system , 2004, Nature.

[33]  Makoto Takemoto,et al.  Identification of the genes that are expressed in the upper layers of the neocortex. , 2004, Cerebral cortex.

[34]  W. Wadsworth,et al.  Assembly and tissue functions of early embryonic laminins and netrins. , 2004, Current opinion in cell biology.

[35]  A. Gurney,et al.  The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons , 2003, Nature Neuroscience.

[36]  A. B. Huber,et al.  Signaling at the growth cone: ligand-receptor complexes and the control of axon growth and guidance. , 2003, Annual review of neuroscience.

[37]  D. Leahy,et al.  Netrin Binds Discrete Subdomains of DCC and UNC5 and Mediates Interactions between DCC and Heparin* , 2003, Journal of Biological Chemistry.

[38]  A. Barclay,et al.  Membrane proteins with immunoglobulin-like domains--a master superfamily of interaction molecules. , 2003, Seminars in immunology.

[39]  G. Otting,et al.  NMR Structure of the Netrin-like Domain (NTR) of Human Type I Procollagen C-Proteinase Enhancer Defines Structural Consensus of NTR Domains and Assesses Potential Proteinase Inhibitory Activity and Ligand Binding* , 2003, Journal of Biological Chemistry.

[40]  M. Tessier-Lavigne,et al.  Netrin 1 mediates spinal cord oligodendrocyte precursor dispersal , 2003, Development.

[41]  T. Kennedy,et al.  Netrin-1 Is a Chemorepellent for Oligodendrocyte Precursor Cells in the Embryonic Spinal Cord , 2003, The Journal of Neuroscience.

[42]  Lindsay Hinck,et al.  Netrin-1/neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis. , 2003, Developmental cell.

[43]  A. Chédotal,et al.  Directional Guidance of Oligodendroglial Migration by Class 3 Semaphorins and Netrin-1 , 2002, The Journal of Neuroscience.

[44]  L. Astic,et al.  Expression of netrin-1 and netrin-1 receptor, DCC, in the rat olfactory nerve pathway during development and axonal regeneration , 2002, Neuroscience.

[45]  S. Itohara,et al.  Complementary expression and neurite outgrowth activity of netrin-G subfamily members , 2002, Mechanisms of Development.

[46]  N. Tamamaki,et al.  Guidance of glial precursor cell migration by secreted cues in the developing optic nerve. , 2001, Development.

[47]  Yukitaka Ushio,et al.  A Role of Netrin-1 in the Formation of the Subcortical Structure Striatum: Repulsive Action on the Migration of Late-Born Striatal Neurons , 2001, The Journal of Neuroscience.

[48]  T. Kennedy,et al.  Widespread Expression of Netrin-1 by Neurons and Oligodendrocytes in the Adult Mammalian Spinal Cord , 2001, The Journal of Neuroscience.

[49]  S. Itohara,et al.  Netrin-G1: a Novel Glycosyl Phosphatidylinositol-Linked Mammalian Netrin That Is Functionally Divergent from Classical Netrins , 2000, The Journal of Neuroscience.

[50]  J. Sanes,et al.  Identification and expression of mouse netrin-4 , 2000, Mechanisms of Development.

[51]  R. Ogata,et al.  Distal Recognition Site for Classical Pathway Convertase Located in the C345C/Netrin Module of Complement Component C51 , 2000, The Journal of Immunology.

[52]  R. Hoffmann,et al.  Glycosaminoglycan-binding properties and secondary structure of the C-terminus of netrin-1. , 2000, Biochemical and biophysical research communications.

[53]  C. Sotelo,et al.  Netrin 1 acts as an attractive or as a repulsive cue for distinct migrating neurons during the development of the cerebellar system. , 2000, Development.

[54]  J. Mott,et al.  Post-translational Proteolytic Processing of Procollagen C-terminal Proteinase Enhancer Releases a Metalloproteinase Inhibitor* , 2000, The Journal of Biological Chemistry.

[55]  W. Wadsworth,et al.  Netrin UNC-6 and the Regulation of Branching and Extension of Motoneuron Axons from the Ventral Nerve Cord of Caenorhabditis elegans , 1999, The Journal of Neuroscience.

[56]  V. Y. Wong,et al.  Cellular expression of a leech netrin suggests roles in the formation of longitudinal nerve tracts and in regional innervation of peripheral targets. , 1999, Journal of neurobiology.

[57]  Mu-ming Poo,et al.  A Ligand-Gated Association between Cytoplasmic Domains of UNC5 and DCC Family Receptors Converts Netrin-Induced Growth Cone Attraction to Repulsion , 1999, Cell.

[58]  D. Gilbert,et al.  Netrin-3, a Mouse Homolog of Human NTN2L, Is Highly Expressed in Sensory Ganglia and Shows Differential Binding to Netrin Receptors , 1999, The Journal of Neuroscience.

[59]  K. Yamakawa,et al.  DSCAM: a novel member of the immunoglobulin superfamily maps in a Down syndrome region and is involved in the development of the nervous system. , 1998, Human molecular genetics.

[60]  F. J. Livesey,et al.  Netrin and Netrin Receptor Expression in the Embryonic Mammalian Nervous System Suggests Roles in Retinal, Striatal, Nigral, and Cerebellar Development , 1997, Molecular and Cellular Neuroscience.

[61]  Michael S. Deiner,et al.  Netrin-1 and DCC Mediate Axon Guidance Locally at the Optic Disc: Loss of Function Leads to Optic Nerve Hypoplasia , 1997, Neuron.

[62]  M. Masu,et al.  Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors , 1997, Nature.

[63]  R. Weinberg,et al.  Phenotype of mice lacking functional Deleted in colorectal cancer (Dec) gene , 1997, Nature.

[64]  Hao Wang,et al.  Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System , 1996, Cell.

[65]  M. Masu,et al.  Deleted in Colorectal Cancer (DCC) Encodes a Netrin Receptor , 1996, Cell.

[66]  J. Culotti,et al.  UNC-40, a C. elegans Homolog of DCC (Deleted in Colorectal Cancer), Is Required in Motile Cells Responding to UNC-6 Netrin Cues , 1996, Cell.

[67]  Y. Jan,et al.  frazzled Encodes a Drosophila Member of the DCC Immunoglobulin Subfamily and Is Required for CNS and Motor Axon Guidance , 1996, Cell.

[68]  M. Seeger,et al.  Guidance Cues at the Drosophila CNS Midline: Identification and Characterization of Two Drosophila Netrin/UNC-6 Homologs , 1996, Neuron.

[69]  J. Tschopp,et al.  The death domain motif found in Fas (Apo‐1) and TNF receptor is present in proteins involved in apoptosis and axonal guidance , 1995, FEBS letters.

[70]  M. Tessier-Lavigne,et al.  The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons , 1995, Cell.

[71]  W. Dreyer,et al.  Neogenin, an avian cell surface protein expressed during terminal neuronal differentiation, is closely related to the human tumor suppressor molecule deleted in colorectal cancer , 1994, The Journal of cell biology.

[72]  Timothy E. Kennedy,et al.  Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord , 1994, Cell.

[73]  T. Jessell,et al.  The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6 , 1994, Cell.

[74]  Kathleen R. Cho,et al.  The DCC gene: structural analysis and mutations in colorectal carcinomas. , 1994, Genomics.

[75]  J. Culotti,et al.  UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans , 1992, Neuron.

[76]  D. Hall,et al.  The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans , 1990, Neuron.

[77]  M. Tessier-Lavigne,et al.  Netrins and their receptors. , 2007, Advances in experimental medicine and biology.

[78]  J. Verhaagen,et al.  Proteoglycans as modulators of axon guidance cue function. , 2007, Advances in experimental medicine and biology.

[79]  L. Patthy,et al.  The NTR module: Domains of netrins, secreted frizzled related proteins, and type I procollagen C‐proteinase enhancer protein are homologous with tissue inhibitors of metalloproteases , 1999, Protein science : a publication of the Protein Society.