Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase
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D. Vertommen | C. Proud | E. M. Smith | X. Wang | M. Rider | G. Herinckx | N. Hussain | S. P. Ruys
[1] S. Burchill,et al. Detection and characterisation of multi-drug resistance protein 1 (MRP-1) in human mitochondria , 2012, British Journal of Cancer.
[2] C. Proud,et al. Insights into the regulation of eukaryotic elongation factor 2 kinase and the interplay between its domains , 2011, The Biochemical journal.
[3] J. Duley,et al. Vincristine pharmacodynamics and pharmacogenetics in children with cancer: A limited‐sampling, population modelling approach , 2011, Journal of paediatrics and child health.
[4] B. Turk,et al. Purification and characterization of tagless recombinant human elongation factor 2 kinase (eEF-2K) expressed in Escherichia coli. , 2011, Protein expression and purification.
[5] Steven P. Smith,et al. Identification of calmodulin and MlcC as light chains for Dictyostelium myosin-I isozymes. , 2011, Biochemistry.
[6] T. Alain,et al. Pharmacological and Genetic Evaluation of Proposed Roles of Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase (MEK), Extracellular Signal-regulated Kinase (ERK), and p90RSK in the Control of mTORC1 Protein Signaling by Phorbol Esters* , 2011, The Journal of Biological Chemistry.
[7] L. Runnels,et al. TRPM6 and TRPM7: A Mul-TRP-PLIK-cation of channel functions. , 2011, Current pharmaceutical biotechnology.
[8] J. Bonner. Dictyostelium discoideum , 2011 .
[9] Ora Schueler-Furman,et al. Autophosphorylation Activates Dictyostelium Myosin II Heavy Chain Kinase A by Providing a Ligand for an Allosteric Binding Site in the α-Kinase Domain* , 2010, The Journal of Biological Chemistry.
[10] Brian D. Marsden,et al. High-throughput production of human proteins for crystallization: The SGC experience , 2010, Journal of structural biology.
[11] Wen Hwa Lee,et al. Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation , 2010, PLoS biology.
[12] Zongchao Jia,et al. Crystal Structure of the α-Kinase Domain of Dictyostelium Myosin Heavy Chain Kinase A , 2010, Science Signaling.
[13] Manolis Kellis,et al. The Tasmanian Devil Transcriptome Reveals Schwann Cell Origins of a Clonally Transmissible Cancer , 2009, Science.
[14] R. Pinkerton,et al. Vincristine: Can its therapeutic index be enhanced? , 2009, Pediatric blood & cancer.
[15] Shelly Lachish,et al. Transmission dynamics of Tasmanian devil facial tumor disease may lead to disease-induced extinction. , 2009, Ecology.
[16] G. Mei,et al. Monomer-dimer equilibrium in glutathione transferases: a critical re-examination. , 2009, Biochemistry.
[17] S. W. Crawley,et al. Identification of dimer interactions required for the catalytic activity of the TRPM7 alpha-kinase domain. , 2009, The Biochemical journal.
[18] Menna E. Jones,et al. Demography, disease and the devil: life-history changes in a disease-affected population of Tasmanian devils (Sarcophilus harrisii). , 2009, The Journal of animal ecology.
[19] Alexey I Nesvizhskii,et al. Comparison of MS(2)-only, MSA, and MS(2)/MS(3) methodologies for phosphopeptide identification. , 2009, Journal of proteome research.
[20] E. Murchison. Clonally transmissible cancers in dogs and Tasmanian devils , 2008, Oncogene.
[21] A. Castor,et al. Vincristine pharmacokinetics is related to clinical outcome in children with standard risk acute lymphoblastic leukemia , 2008, British journal of haematology.
[22] B. Viollet,et al. AMP-activated Protein Kinase Phosphorylates and Desensitizes Smooth Muscle Myosin Light Chain Kinase*♦ , 2008, Journal of Biological Chemistry.
[23] S. W. Crawley,et al. Determinants for substrate phosphorylation by Dictyostelium myosin II heavy chain kinases A and B and eukaryotic elongation factor-2 kinase. , 2008, Biochimica et biophysica acta.
[24] C. Proud,et al. cdc2–cyclin B regulates eEF2 kinase activity in a cell cycle‐ and amino acid‐dependent manner , 2008, The EMBO journal.
[25] C. Figdor,et al. Massive Autophosphorylation of the Ser/Thr-Rich Domain Controls Protein Kinase Activity of TRPM6 and TRPM7 , 2008, PloS one.
[26] N. Eberle,et al. Combination chemotherapy in feline lymphoma: treatment outcome, tolerability, and duration in 23 cats. , 2008, Journal of veterinary internal medicine.
[27] Richard D. Smith,et al. Does trypsin cut before proline? , 2008, Journal of proteome research.
[28] Katherine Belov,et al. Transmission of a fatal clonal tumor by biting occurs due to depleted MHC diversity in a threatened carnivorous marsupial , 2007, Proceedings of the National Academy of Sciences.
[29] C. Proud,et al. PRAS40 Is a Target for Mammalian Target of Rapamycin Complex 1 and Is Required for Signaling Downstream of This Complex* , 2007, Journal of Biological Chemistry.
[30] M. Hedhammar,et al. Z(basic)--a novel purification tag for efficient protein recovery. , 2007, Journal of chromatography. A.
[31] K. Belov,et al. Characterization of major histocompatibility complex class I and class II genes from the Tasmanian devil (Sarcophilus harrisii) , 2007, Immunogenetics.
[32] D. Levêque,et al. Molecular Pharmacokinetics of Catharanthus (Vinca) Alkaloids , 2007, Journal of clinical pharmacology.
[33] C. Proud,et al. 21 Regulation of Translation Elongation and the Cotranslational Protein Targeting Pathway , 2007 .
[34] P. Mittl,et al. Sel1-like repeat proteins in signal transduction. , 2007, Cellular signalling.
[35] M. Mann,et al. Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks , 2006, Cell.
[36] Clare E. Hawkins,et al. Emerging disease and population decline of an island endemic, the Tasmanian devil Sarcophilus harrisii , 2006 .
[37] D. Vertommen,et al. Insulin Antagonizes Ischemia-induced Thr172 Phosphorylation of AMP-activated Protein Kinase α-Subunits in Heart via Hierarchical Phosphorylation of Ser485/491* , 2006, Journal of Biological Chemistry.
[38] A. Pearse,et al. Allograft theory: Transmission of devil facial-tumour disease , 2006, Nature.
[39] A. Perraud,et al. The Channel Kinases TRPM6 and TRPM7 Are Functionally Nonredundant* , 2005, Journal of Biological Chemistry.
[40] Meredith C. Hermosura,et al. A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[41] A. Nairn,et al. Channel Function Is Dissociated from the Intrinsic Kinase Activity and Autophosphorylation of TRPM7/ChaK1* , 2005, Journal of Biological Chemistry.
[42] W. Kamps,et al. Vincristine pharmacokinetics and response to vincristine monotherapy in an up-front window study of the Dutch Childhood Leukaemia Study Group (DCLSG). , 2005, European journal of cancer.
[43] I. McGregor,et al. Rapid quantitation of fluoxetine and norfluoxetine in serum by micro-disc solid-phase extraction with high-performance liquid chromatography-ultraviolet absorbance detection. , 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[44] A. Ryazanov,et al. Alpha-kinases: analysis of the family and comparison with conventional protein kinases. , 2004, Progress in biophysics and molecular biology.
[45] Wei Li,et al. Mutations Linked to Leukoencephalopathy with Vanishing White Matter Impair the Function of the Eukaryotic Initiation Factor 2B Complex in Diverse Ways , 2004, Molecular and Cellular Biology.
[46] Christopher G. Proud,et al. A Novel mTOR-Regulated Phosphorylation Site in Elongation Factor 2 Kinase Modulates the Activity of the Kinase and Its Binding to Calmodulin , 2004, Molecular and Cellular Biology.
[47] C. Proud,et al. Stimulation of the AMP-activated Protein Kinase Leads to Activation of Eukaryotic Elongation Factor 2 Kinase and to Its Phosphorylation at a Novel Site, Serine 398* , 2004, Journal of Biological Chemistry.
[48] W. Kamps,et al. Influence of functional polymorphisms of the MDR1 gene on vincristine pharmacokinetics in childhood acute lymphoblastic Leukemia , 2003, Clinical pharmacology and therapeutics.
[49] Veterinary Co-operative Oncology Group - Common Terminology Criteria for Adverse Events (VCOG-CTCAE) following chemotherapy or biological antineoplastic therapy in dogs and cats v1.0. , 2004, Veterinary and comparative oncology.
[50] D. Vertommen,et al. Identification of Phosphorylation Sites in AMP-activated Protein Kinase (AMPK) for Upstream AMPK Kinases and Study of Their Roles by Site-directed Mutagenesis* , 2003, Journal of Biological Chemistry.
[51] M. Herrtage,et al. Owners' assessments of their dog's quality of life during palliative chemotherapy for lymphoma. , 2002, The Journal of small animal practice.
[52] C. Proud,et al. Regulation of peptide-chain elongation in mammalian cells. , 2002, European journal of biochemistry.
[53] A. Ryazanov,et al. Regulation of elongation factor-2 kinase by pH. , 2002, Biochemistry.
[54] D. Vertommen,et al. Activation of AMP-Activated Protein Kinase Leads to the Phosphorylation of Elongation Factor 2 and an Inhibition of Protein Synthesis , 2002, Current Biology.
[55] U. Giger,et al. Comparison of platelet count recovery with use of vincristine and prednisone or prednisone alone for treatment for severe immune-mediated thrombocytopenia in dogs. , 2002, Journal of the American Veterinary Medical Association.
[56] Philip R. Cohen,et al. A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38δ , 2001, The EMBO journal.
[57] C. Proud,et al. Regulation of elongation factor 2 kinase by p90RSK1 and p70 S6 kinase , 2001, The EMBO journal.
[58] J Kuriyan,et al. Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity. , 2001, Molecular cell.
[59] Kathryn S. Lilley,et al. Phosphorylation of elongation factor-2 kinase on serine 499 by cAMP-dependent protein kinase induces Ca(2+)/calmodulin-independent activity , 2001 .
[60] K. Lilley,et al. Phosphorylation of elongation factor-2 kinase on serine 499 by cAMP-dependent protein kinase induces Ca2+/calmodulin-independent activity. , 2001, The Biochemical journal.
[61] A. Ryazanov,et al. Mapping the functional domains of elongation factor-2 kinase. , 2000, Biochemistry.
[62] C. Smythe,et al. ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK , 1999, Oncogene.
[63] N. Redpath,et al. Analysis of the domain structure of elongation factor‐2 kinase by mutagenesis , 1999, FEBS letters.
[64] A. Ryazanov,et al. Alpha-kinases: a new class of protein kinases with a novel catalytic domain , 1999, Current Biology.
[65] W. Kamps,et al. Vincristine pharmacokinetics after repetitive dosing in children , 1999, Cancer Chemotherapy and Pharmacology.
[66] G. S. Price,et al. Use of body surface area (BSA)-based dosages to calculate chemotherapeutic drug dose in dogs: I. Potential problems with current BSA formulae. , 1998, Journal of veterinary internal medicine.
[67] K. Gelmon,et al. Validation of a high-performance liquid chromatographic assay method for quantification of total vincristine sulfate in human plasma following administration of vincristine sulfate liposome injection. , 1997, Journal of pharmaceutical and biomedical analysis.
[68] D. Vertommen,et al. Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades* , 1997, The Journal of Biological Chemistry.
[69] M Wiedmann,et al. Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[70] A. Rhoads,et al. Sequence motifs for calmodulin recognition , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[71] A. Legendre,et al. Marked neutropenia in five tumor-bearing cats one week following single-agent vincristine sulfate chemotherapy. , 1996, Veterinary clinical pathology.
[72] C. Proud,et al. Regulation of translation elongation factor‐2 by insulin via a rapamycin‐sensitive signalling pathway. , 1996, The EMBO journal.
[73] S. D. de Graaf,et al. Vincristine disposition in children with acute lymphoblastic leukemia. , 1995, Medical and pediatric oncology.
[74] M. Bally,et al. Liposome encapsulated vincristine: preclinical toxicologic and pharmacologic comparison with free vincristine and empty liposomes in mice, rats and dogs , 1994, Anti-cancer drugs.
[75] C. Proud,et al. Cyclic AMP-dependent protein kinase phosphorylates rabbit reticulocyte elongation factor-2 kinase and induces calcium-independent activity. , 1993, The Biochemical journal.
[76] C. Proud,et al. Purification and phosphorylation of elongation factor-2 kinase from rabbit reticulocytes. , 1993, European journal of biochemistry.
[77] C. Proud,et al. Identification of the phosphorylation sites in elongation factor‐2 from rabbit reticulocytes , 1991, FEBS letters.
[78] M. Jordan,et al. Mechanism of inhibition of cell proliferation by Vinca alkaloids. , 1991, Cancer research.
[79] L. Ovchinnikov,et al. Three phosphorylation sites in elongation factor 2 , 1990, FEBS letters.
[80] P. D. de Jong,et al. Ligation-independent cloning of PCR products (LIC-PCR). , 1990, Nucleic acids research.
[81] J. Gariépy,et al. Dictyostelium myosin II heavy-chain kinase A is activated by autophosphorylation: studies with Dictyostelium myosin II and synthetic peptides. , 1990, Biochemistry.
[82] O. Nygård,et al. Functional properties of phosphorylated elongation factor 2. , 1990, European journal of biochemistry.
[83] A. Ryazanov,et al. Mechanism of elongation factor 2 (EF‐2) inactivation upon phosphorylation Phosphorylated EF‐2 is unable to catalyze translocation , 1989, FEBS letters.
[84] A. Nairn,et al. Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2. , 1987, The Journal of biological chemistry.
[85] A. Ryazanov. Ca2+/calmodulin‐dependent phosphorylation of elongation factor 2 , 1987, FEBS letters.
[86] G. Côté,et al. Purification and characterization of a myosin heavy chain kinase from Dictyostelium discoideum. , 1987, The Journal of biological chemistry.
[87] A. Nairn,et al. Identification of calmodulin-dependent protein kinase III and its major Mr 100,000 substrate in mammalian tissues. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[88] E. Macewen,et al. Vincristine for treatment of transmissible venereal tumor in the dog--. , 1982, Journal of the American Veterinary Medical Association.
[89] D. Morton,et al. Animal models for the comparative assessment of neurotoxicity following repeated administration of vinca alkaloids. , 1979, Cancer treatment reports.
[90] P. Cohen,et al. The substrate specificity of adenosine 3':5'-cyclic monophosphate-dependent protein kinase of rabbit skeletal muscle. , 1977, The Biochemical journal.
[91] M. M. Bradford. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.
[92] D. Love,et al. Studies on feline lymphosarcoma in the Sydney area. , 1974, The Australian journal of experimental biology and medical science.
[93] W. Wooster,et al. Crystal structure of , 2005 .
[94] U. K. Laemmli,et al. Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.
[95] T. Dawson,et al. Standard metabolism, body temperature, and surface areas of Australian marsupials. , 1970, The American journal of physiology.
[96] E. Gehan,et al. The determinatio of the number of patients required in a preliminary and a follow-up trial of a new chemotherapeutic agent. , 1961, Journal of chronic diseases.