Regenerative Medicine of Bone and Teeth : with special references to biological principles, problems and their indicators

So much anticipation from the side of need patients has been caused by recent advances in tissue engineering technology. However, it seems that effective results can be hardly achieved unless we establish the proper principles for this technology. In this review paper, therefore, we discuss these problems and indicators from the viewpoint of the biological principles of hard tissue regeneration, which are as follows: 1) principles of hard tissue reconstruction, 2) bio-functional nano-composites for regeneration of hard tissue, 3) industrialization of growth factors for hard tissue reconstruction, 4) history and problems of medical ceramic materials, and 5) dentin matrices as a new autograft material for osseous regeneration.

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