Discovery of 9-(1-anilinoethyl)-2-morpholino-4-oxo-pyrido[1,2-a]pyrimidine-7-carboxamides as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours.
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S. Green | B. Barlaam | S. Degorce | R. Morgentin | P. Plé | S. Cosulich | F. Giordanetto | Urs J Hancox | L. Hennequin | T. Inghardt | M. Fitzek | Lara Ward | C. Lambert-van der Brempt | Sarah L. Pass | Twana Saleh