Catalytic activity of Manganese(II)-Gluconate complex in reactions of Hydrogen Peroxide

Kinetic studies of the hydrogen peroxide decomposition catalyzed by the dimeric Mn(II)-gluconate complex, in alkaline medium, showed evidence for the oxidative cleavage of the ligand, leading to the formation of formaldehyde as one of the products. In the presence of a large excess of other hydroxylated substrates, such as methanol or ethylene glycol, a significant increase in the yield of formaldehyde was observed, corroborating the observed peroxidase activity in this system, in addition to the catalase activity. Oxygen free radicals were detected as intermediates of reaction, by ESR spectroscopy using the spintrapping method, only under aerobic conditions. Therefore, a nonradical mechanism was proposed for the reaction, based on the formation of a peroxo-Mn(II) complex, and its further reduction to the previous Mn(II) species. © 1994 John Wiley & Sons, Inc.

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