HYPOHIDROTIC (OR ANHIDROTIC) ECTODERMAL DYSPLASIA—AN APPRAISAL OF DIAGNOSTIC METHODS *

A study has been carried out in 20 members of 5 unrelated families to confirm the diagnosis of hypohidrotic ectodermal dysplasia (HED) in 5 young males, and to detect possible female carriers. The history and the clinical examination were supplemented by sweat testing and plastic imprinting over selected areas of the palm, pore‐counting, and dermatoglyphic analysis. Findings of importance include definitely abnormal imprints in 3 mothers and in 4 affected individuals, good sweat gland function in one of the affected individuals, and unilateral or bilateral high maximal and angles in all affected individuals and in 4 mothers.