p62 in Cancer: Signaling Adaptor Beyond Autophagy

[1]  S. Subramaniam,et al.  p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells. , 2016, Cancer cell.

[2]  Mark Ellisman,et al.  NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria , 2016, Cell.

[3]  A. Durán,et al.  Amino Acid Activation of mTORC1 by a PB1-Domain-Driven Kinase Complex Cascade. , 2015, Cell reports.

[4]  J. Debnath,et al.  Autophagy at the crossroads of catabolism and anabolism , 2015, Nature Reviews Molecular Cell Biology.

[5]  Brian Ruffell,et al.  Macrophages and therapeutic resistance in cancer. , 2015, Cancer cell.

[6]  Lorenzo Galluzzi,et al.  Metabolic Control of Autophagy , 2014, Cell.

[7]  M. Karin,et al.  ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development. , 2014, Cancer cell.

[8]  M. Tschöp,et al.  A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose tissue inflammation in obesity. , 2014, Cell metabolism.

[9]  Christian M. Metallo,et al.  Metabolic reprogramming of stromal fibroblasts through p62-mTORC1 signaling promotes inflammation and tumorigenesis. , 2014, Cancer cell.

[10]  M. Karin,et al.  Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. , 2014, Cell metabolism.

[11]  D. Green,et al.  To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate , 2014, Cell.

[12]  M. Pasparakis,et al.  K63 polyubiquitination and activation of mTOR by the p62-TRAF6 complex in nutrient-activated cells. , 2013, Molecular cell.

[13]  T. Deerinck,et al.  Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice. , 2013, The Journal of clinical investigation.

[14]  K. Guan,et al.  Amino acid signalling upstream of mTOR , 2013, Nature Reviews Molecular Cell Biology.

[15]  E. White.  Deconvoluting the context-dependent role for autophagy in cancer , 2012, Nature Reviews Cancer.

[16]  Aleksey A. Porollo,et al.  p62 is a key regulator of nutrient sensing in the mTORC1 pathway. , 2011, Molecular cell.

[17]  A. Kimmelman,et al.  The dynamic nature of autophagy in cancer. , 2011, Genes & development.

[18]  Scott E. Kern,et al.  Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis , 2011, Nature.

[19]  J. Tschopp,et al.  A role for mitochondria in NLRP3 inflammasome activation , 2011, Nature.

[20]  M. Karin,et al.  Immunity, Inflammation, and Cancer , 2010, Cell.

[21]  M. Diaz-Meco,et al.  p62 at the Crossroads of Autophagy, Apoptosis, and Cancer , 2009, Cell.

[22]  Masaaki Komatsu,et al.  Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice , 2007, Cell.

[23]  D. Benbrook,et al.  Nature Reviews Cancer , 2003 .

[24]  P. Lawrence,et al.  Genes in development , 1977, Nature.