Iodothyronine deiodinase enzyme activities in bone

[1]  A. Boyde,et al.  A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism. , 2008, Molecular endocrinology.

[2]  A. Bianco,et al.  Expression patterns of WSB-1 and USP-33 underlie cell-specific posttranslational control of type 2 deiodinase in the rat brain. , 2007, Endocrinology.

[3]  A. Boyde,et al.  Thyroid status during skeletal development determines adult bone structure and mineralization. , 2007, Molecular endocrinology.

[4]  A. Boyde,et al.  Thyroid hormone excess rather than thyrotropin deficiency induces osteoporosis in hyperthyroidism. , 2007, Molecular endocrinology.

[5]  J. Harney,et al.  Ubiquitination-Induced Conformational Change within the Deiodinase Dimer Is a Switch Regulating Enzyme Activity , 2007, Molecular and Cellular Biology.

[6]  P. Larsen,et al.  Mice with impaired extrathyroidal thyroxine to 3,5,3'-triiodothyronine conversion maintain normal serum 3,5,3'-triiodothyronine concentrations. , 2007, Endocrinology.

[7]  R. Versteeg,et al.  Regulation of type III iodothyronine deiodinase expression in human cell lines. , 2006, Endocrinology.

[8]  T. Visser,et al.  Thyroid hormone transport by the human monocarboxylate transporter 8 and its rate-limiting role in intracellular metabolism. , 2006, Molecular endocrinology.

[9]  A. Uitterlinden,et al.  Evidence for auto/paracrine actions of vitamin D in bone: 1a‐hydroxylase expression and activity in human bone cells , 2006 .

[10]  J. Harney,et al.  Metabolic Instability of Type 2 Deiodinase Is Transferable To Stable Proteins Independently of Subcellular Localization* , 2006, Journal of Biological Chemistry.

[11]  A. Bianco,et al.  Deiodinases: implications of the local control of thyroid hormone action. , 2006, The Journal of clinical investigation.

[12]  S. Fiering,et al.  Type 3 deiodinase is critical for the maturation and function of the thyroid axis. , 2006, The Journal of clinical investigation.

[13]  Sheue-yann Cheng,et al.  Characterization of skeletal phenotypes of TRα1PV and TRβPV mutant mice: implications for tissue thyroid status and T3 target gene expression , 2006, Nuclear receptor signaling.

[14]  J. Samarut,et al.  Thyroid hormones regulate fibroblast growth factor receptor signaling during chondrogenesis. , 2005, Endocrinology.

[15]  Sheue-yann Cheng,et al.  Contrasting Skeletal Phenotypes in Mice with an Identical Mutation Targeted to Thyroid Hormone Receptor α1 or β , 2005 .

[16]  P. Vestergaard,et al.  Influence of Hyper- and Hypothyroidism, and the Effects of Treatment with Antithyroid Drugs and Levothyroxine on Fracture Risk , 2005, Calcified Tissue International.

[17]  J. Harney,et al.  Type 2 iodothyronine deiodinase is the major source of plasma T3 in euthyroid humans. , 2005, The Journal of clinical investigation.

[18]  T. Visser,et al.  Thyroid hormone transporters in health and disease. , 2005, Thyroid : official journal of the American Thyroid Association.

[19]  P. Larsen,et al.  Cellular and structural biology of the deiodinases. , 2005, Thyroid : official journal of the American Thyroid Association.

[20]  Francis Y. Lee,et al.  μ-Calpain Regulates Receptor Activator of NF-κB Ligand (RANKL)-supported Osteoclastogenesis via NF-κB Activation in RAW 264.7 Cells* , 2005, Journal of Biological Chemistry.

[21]  C. Tabin,et al.  The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate , 2005, Nature Cell Biology.

[22]  A. Uitterlinden,et al.  11β-Hydroxysteroid Dehydrogenase Expression and Glucocorticoid Synthesis Are Directed by a Molecular Switch during Osteoblast Differentiation , 2005 .

[23]  E. Murphy,et al.  The thyroid and the skeleton , 2004, Clinical endocrinology.

[24]  Jacques Samarut,et al.  Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[25]  T. Visser,et al.  Iodothyronine levels in the human developing brain: major regulatory roles of iodothyronine deiodinases in different areas. , 2004, The Journal of clinical endocrinology and metabolism.

[26]  S Jaques,et al.  Differential expression of iodothyronine deiodinase type 2 in growth plates of chickens divergently selected for incidence of tibial dyschondroplasia. , 2004, Animal genetics.

[27]  R. Goodyear,et al.  Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[28]  T. Visser,et al.  Identification of Monocarboxylate Transporter 8 as a Specific Thyroid Hormone Transporter* , 2003, Journal of Biological Chemistry.

[29]  V. Galton,et al.  Determinants of iodothyronine deiodinase activities in rodent uterus. , 2003, Endocrinology.

[30]  J. Bassett,et al.  The molecular actions of thyroid hormone in bone , 2003, Trends in Endocrinology & Metabolism.

[31]  O. Chassande Do unliganded thyroid hormone receptors have physiological functions? , 2003, Journal of molecular endocrinology.

[32]  Sheue-yann Cheng,et al.  A thyrotoxic skeletal phenotype of advanced bone formation in mice with resistance to thyroid hormone. , 2003, Molecular endocrinology.

[33]  H. Kronenberg,et al.  Developmental regulation of the growth plate , 2003, Nature.

[34]  S. Fiering,et al.  The gene locus encoding iodothyronine deiodinase type 3 (Dio3) is imprinted in the fetus and expresses antisense transcripts. , 2002, Endocrinology.

[35]  S. Shalet,et al.  Dexamethasone inhibits and thyroid hormone promotes differentiation of mouse chondrogenic ATDC5 cells. , 2002, Bone.

[36]  V. Darras,et al.  Differential expression of iodothyronine deiodinases in chicken tissues during the last week of embryonic development. , 2002, General and comparative endocrinology.

[37]  W. Klootwijk,et al.  Substitution of cysteine for a conserved alanine residue in the catalytic center of type II iodothyronine deiodinase alters interaction with reducing cofactor. , 2002, Endocrinology.

[38]  K. Nakao,et al.  A novel interaction between thyroid hormones and 1,25(OH)(2)D(3) in osteoclast formation. , 2002, Biochemical and biophysical research communications.

[39]  J. Samarut,et al.  Thyroid hormone activates fibroblast growth factor receptor-1 in bone. , 2002, Molecular endocrinology.

[40]  K. Nakao,et al.  Thyroid Hormones Promote Chondrocyte Differentiation in Mouse ATDC5 Cells and Stimulate Endochondral Ossification in Fetal Mouse Tibias Through Iodothyronine Deiodinases in the Growth Plate , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[41]  P. Larsen,et al.  Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. , 2002, Endocrine reviews.

[42]  S. Fiering,et al.  Targeted disruption of the type 2 selenodeiodinase gene (DIO2) results in a phenotype of pituitary resistance to T4. , 2001, Molecular endocrinology.

[43]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[44]  P. Larsen,et al.  Transcriptional regulation of iodothyronine deiodinases during embryonic development , 2001, Molecular and Cellular Endocrinology.

[45]  D. D. Brown,et al.  Timing of metamorphosis and the onset of the negative feedback loop between the thyroid gland and the pituitary is controlled by type II iodothyronine deiodinase in Xenopus laevis , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[46]  D. Bauer,et al.  Risk for Fracture in Women with Low Serum Levels of Thyroid-Stimulating Hormone , 2001, Annals of Internal Medicine.

[47]  D. Stevens,et al.  Thyroid hormone acts directly on growth plate chondrocytes to promote hypertrophic differentiation and inhibit clonal expansion and cell proliferation. , 2000, Endocrinology.

[48]  L. Sachs,et al.  Dual functions of thyroid hormone receptors during Xenopus development. , 2000, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

[49]  D. Forrest,et al.  Type 2 iodothyronine deiodinase expression in the cochlea before the onset of hearing. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[50]  M. Segni,et al.  Special features of Graves' disease in early childhood. , 1999, Thyroid : official journal of the American Thyroid Association.

[51]  J. Bernal,et al.  Expression of Type 2 Iodothyronine Deiodinase in Hypothyroid Rat Brain Indicates an Important Role of Thyroid Hormone in the Development of Specific Primary Sensory Systems , 1999, The Journal of Neuroscience.

[52]  V. Galton,et al.  Printed in U.S.A. Copyright © 1999 by The Endocrine Society Expression Profiles of the Three Iodothyronine , 2022 .

[53]  H. van Toor,et al.  Ontogeny of iodothyronine deiodinases in human liver. , 1998, The Journal of clinical endocrinology and metabolism.

[54]  M. Itoman,et al.  Thyroid hormone-induced chondrocyte terminal differentiation in rat femur organ culture , 1998, Cell and Tissue Research.

[55]  D. Lacey,et al.  Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation , 1998, Cell.

[56]  J. Köhrle,et al.  Selenoproteins are expressed in fetal human osteoblast-like cells. , 1998, Biochemical and biophysical research communications.

[57]  R. Bland,et al.  Thyroid hormone, vitamin D and retinoid receptor expression and signalling in primary cultures of rat osteoblastic and immortalised osteosarcoma cells. , 1997, The Journal of endocrinology.

[58]  A. Poole,et al.  In serum‐free culture thyroid hormones can induce full expression of chondrocyte hypertrophy leading to matrix calcification , 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[59]  R. Franceschi,et al.  Effects of differentiation and transforming growth factor β1 on PTH/PTHrP receptor mRNA levels in MC3T3‐E1 cells , 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[60]  A. Reddi,et al.  Thyroxine is the serum factor that regulates morphogenesis of columnar cartilage from isolated chondrocytes in chemically defined medium , 1994, The Journal of cell biology.

[61]  M. Berry,et al.  Physiological and genetic analyses of inbred mouse strains with a type I iodothyronine 5' deiodinase deficiency. , 1993, The Journal of clinical investigation.

[62]  M. Mori,et al.  Establishment and Characterization of a Simian Virus 40‐Immortalized Osteoblastic Cell Line from Normal Human Bone , 1993, Japanese journal of cancer research : Gann.

[63]  T. Tschan,et al.  Induction of proliferation or hypertrophy of chondrocytes in serum-free culture: the role of insulin-like growth factor-I, insulin, or thyroxine , 1992, The Journal of cell biology.

[64]  M. Pierre,et al.  Induction of 5‐Deiodinase Activity in Astroglial Cells by 12‐O‐Tetradecanoylphorbol 13‐Acetate and Fibroblast Growth Factors , 1991, Journal of neurochemistry.

[65]  L. Mosekilde,et al.  Effects of thyroid hormones on bone and mineral metabolism. , 1990, Endocrinology and metabolism clinics of North America.

[66]  J. Hershman,et al.  Thyroid hormone 5′‐deiodinase activity, nuclear binding, and effects on mitogenesis in umr‐106 osteoblastic osteosarcoma cells , 1989, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[67]  J. L. Leonard,et al.  Dibutyryl cAMP induction of type II 5'deiodinase activity in rat brain astrocytes in culture. , 1988, Biochemical and biophysical research communications.

[68]  S. Rivkees,et al.  Long-term growth in juvenile acquired hypothyroidism: the failure to achieve normal adult stature. , 1987, The New England journal of medicine.

[69]  J. Aubin,et al.  Mineralized bone nodules formedin vitro from enzymatically released rat calvaria cell populations , 1986, Calcified Tissue International.

[70]  H. Samuels,et al.  Depletion of L-3,5,3'-triiodothyronine and L-thyroxine in euthyroid calf serum for use in cell culture studies of the action of thyroid hormone. , 1979, Endocrinology.

[71]  E. Reiter Normal and aberrant growth , 2007 .

[72]  S. Fiering,et al.  Targeted disruption of the type 1 selenodeiodinase gene (Dio1) results in marked changes in thyroid hormone economy in mice. , 2006, Endocrinology.

[73]  J. Harney,et al.  Type 2 iodothyronine selenodeiodinase is expressed throughout the mouse skeleton and in the MC3T3-E1 mouse osteoblastic cell line during differentiation. , 2005, Endocrinology.

[74]  森村 匡志 Expression of type 2 iodothyronine deiodinase in human osteoblast is stimulated by thyrotropin , 2005 .

[75]  Francis Y. Lee,et al.  mu-Calpain regulates receptor activator of NF-kappaB ligand (RANKL)-supported osteoclastogenesis via NF-kappaB activation in RAW 264.7 cells. , 2005, The Journal of biological chemistry.

[76]  Sheue-yann Cheng,et al.  Contrasting skeletal phenotypes in mice with an identical mutation targeted to thyroid hormone receptor alpha1 or beta. , 2005, Molecular endocrinology.

[77]  Ahmed Mansouri,et al.  Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene. , 2002, Molecular endocrinology.

[78]  J. Samarut,et al.  Molecular mechanisms of thyroid hormone effects on bone growth and function. , 2002, Molecular genetics and metabolism.

[79]  J. Britto,et al.  Osteoblasts mediate thyroid hormone stimulation of osteoclastic bone resorption. , 1994, Endocrinology.

[80]  T. Visser,et al.  Impairment of the selenoenzyme type I iodothyronine deiodinase in C3H/He mice. , 1993, Endocrinology.

[81]  R. Williams,et al.  Williams Textbook of endocrinology , 1985 .