FRA3B and other common fragile sites: the weakest links
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[1] F. Welch,et al. Causes and Consequences , 2017, Nature.
[2] D. Beer,et al. Molecular characterization of FRAXB and comparative common fragile site instability in cancer cells , 2002, Genes, chromosomes & cancer.
[3] J. Rowley,et al. Chromosome translocations: dangerous liaisons revisited , 2001, Nature Reviews Cancer.
[4] A. Brenner,et al. WWOX, the FRA16D gene, behaves as a suppressor of tumor growth. , 2001, Cancer research.
[5] K. Mimori,et al. Absence of Msh2 protein expression is associated with alteration in the FHIT locus and Fhit protein expression in colorectal carcinoma. , 2001, Cancer research.
[6] D J Porteous,et al. WWOX: A candidate tumor suppressor gene involved in multiple tumor types , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[7] J. Zucman‐Rossi,et al. Identification of homozygous deletions at chromosome 16q23 in Aflatoxin B1 exposed hepatocellular carcinoma , 2001, Oncogene.
[8] C. Croce,et al. The tumor spectrum in FHIT-deficient mice , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[9] E. Rosato,et al. Fragile histidine triad expression delays tumor development and induces apoptosis in human pancreatic cancer. , 2001, Cancer research.
[10] D. Venzon,et al. Abnormal fragile histidine triad (FHIT) expression in advanced cervical carcinoma: a poor prognostic factor. , 2001, Cancer research.
[11] R. Richards. Fragile and unstable chromosomes in cancer: causes and consequences. , 2001, Trends in genetics : TIG.
[12] W. Miller,et al. Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[13] J. Minna,et al. Successful treatment of primary and disseminated human lung cancers by systemic delivery of tumor suppressor genes using an improved liposome vector. , 2001, Molecular therapy : the journal of the American Society of Gene Therapy.
[14] C. Croce,et al. FHIT gene therapy prevents tumor development in Fhit-deficient mice , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[15] J. Heath,et al. Hyaluronidase Induction of a WW Domain-containing Oxidoreductase That Enhances Tumor Necrosis Factor Cytotoxicity* , 2001, The Journal of Biological Chemistry.
[16] W. Hong,et al. Loss of Fhit expression is a predictor of poor outcome in tongue cancer. , 2001, Cancer research.
[17] C. Croce,et al. Effect of adenoviral transduction of the fragile histidine triad gene into esophageal cancer cells. , 2001, Cancer research.
[18] C. Brenner,et al. The nitrilase superfamily: classification, structure and function , 2001, Genome Biology.
[19] G. Klein,et al. Inactivation of the human fragile histidine triad gene at 3p14.2 in monochromosomal human/mouse microcell hybrid-derived severe combined immunodeficient mouse tumors. , 2000, Cancer research.
[20] L. Roberts,et al. The characterization of the common fragile site FRA16D and its involvement in multiple myeloma translocations. , 2000, Genomics.
[21] F. X. Bosch,et al. Loss of fhit expression in invasive cervical carcinomas and intraepithelial lesions associated with invasive disease. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[22] K. Mimori,et al. Characterization of the human TESTIN gene localized in the FRA7G region at 7q31.2. , 2000, Genomics.
[23] R. Richards,et al. Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells. , 2000, Human molecular genetics.
[24] Stephen W. Scherer,et al. Replication Delay along FRA7H, a Common Fragile Site on Human Chromosome 7, Leads to Chromosomal Instability , 2000, Molecular and Cellular Biology.
[25] K. Huebner,et al. Differential susceptibility of renal carcinoma cell lines to tumor suppression by exogenous Fhit expression. , 2000, Cancer research.
[26] A. McLennan,et al. The Fhit tumor suppressor protein regulates the intracellular concentration of diadenosine triphosphate but not diadenosine tetraphosphate. , 2000, Cancer research.
[27] A. Bednarek,et al. WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer. , 2000, Cancer research.
[28] J. Sgouros,et al. A 700-kb physical map of a region of 16q23.2 homozygously deleted in multiple cancers and spanning the common fragile site FRA16D. , 2000, Cancer research.
[29] R. Richards,et al. Chromosomal fragile site FRA16D and DNA instability in cancer. , 2000, Cancer research.
[30] R. Hruban,et al. Genomic FHIT analysis in RER+ and RER− adenocarcinomas of the pancreas , 2000, Genes, chromosomes & cancer.
[31] C. Croce,et al. Altered expression of Fhit in carcinoma and precarcinomatous lesions of the esophagus. , 2000, Cancer research.
[32] Kathleen R. Cho,et al. Restored expression of fragile histidine triad protein and tumorigenicity of cervical carcinoma cells. , 2000, Journal of the National Cancer Institute.
[33] K. Huebner,et al. The histidine triad superfamily of nucleotide‐binding proteins , 1999, Journal of cellular physiology.
[34] F. Khuri,et al. Loss of Fhit is frequent in stage I non-small cell lung cancer and in the lungs of chronic smokers. , 1999, Cancer research.
[35] L. D. Barnes,et al. The Tumor Suppressor Protein Fhit , 1999, The Journal of Biological Chemistry.
[36] C. Croce,et al. The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[37] J. Minna,et al. Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression. , 1999, Cancer research.
[38] C. Croce,et al. Cancer-specific chromosome alterations in the constitutive fragile region FRA3B. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[39] O. Kallioniemi,et al. Reduced Fhit expression in sporadic and BRCA2-linked breast carcinomas. , 1999, Cancer research.
[40] George Reid,et al. Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines , 1999, Oncogene.
[41] Haojie Huang,et al. Frequent deletions within FRA7G at 7q31.2 in invasive epithelial ovarian cancer , 1999, Genes, chromosomes & cancer.
[42] J. Yokota,et al. Clinicopathological significance of Fhit protein expression in stage I non-small cell lung carcinoma. , 1998, Cancer research.
[43] James M. Roberts,et al. The murine gene p27Kip1 is haplo-insufficient for tumour suppression , 1998, Nature.
[44] Y. Pekarsky,et al. The murine Fhit locus: isolation, characterization, and expression in normal and tumor cells. , 1998, Cancer research.
[45] D. Beer,et al. The murine Fhit gene is highly similar to its human orthologue and maps to a common fragile site region. , 1998, Cancer research.
[46] F. Toledo,et al. A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs. , 1998, Molecular cell.
[47] Y. Pekarsky,et al. Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[48] S. Scherer,et al. Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[49] L. Liotta,et al. Allelic deletion analysis of the FHIT gene predicts poor survival in non-small cell lung cancer. , 1998, Cancer research.
[50] L. D. Barnes,et al. Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[51] R. Espinosa,et al. Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction. , 1998, Human molecular genetics.
[52] F. Kaye,et al. Protein expression and functional analysis of the FHIT gene in human tumor cells. , 1998, Journal of the National Cancer Institute.
[53] C. Croce,et al. Sequence of the FRA3B common fragile region: implications for the mechanism of FHIT deletion. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[54] L. D. Barnes,et al. Replacement of Fhit in cancer cells suppresses tumorigenicity. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[55] D. Beer,et al. Frequent deletions of FHIT and FRA3B in Barrett's metaplasia and esophageal adenocarcinomas , 1997, Oncogene.
[56] J. Samet,et al. Molecular damage in the bronchial epithelium of current and former smokers. , 1997, Journal of the National Cancer Institute.
[57] J S Lee,et al. Clonal genetic alterations in the lungs of current and former smokers. , 1997, Journal of the National Cancer Institute.
[58] C. Croce,et al. Positions of chromosome 3p14.2 fragile sites (FRA3B) within the FHIT gene. , 1997, Cancer research.
[59] J. Roth,et al. Inhibition of esophageal cancer proliferation by adenovirally mediated delivery of p16INK4. , 1996, Cancer gene therapy.
[60] L. D. Barnes,et al. Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase. , 1996, Biochemistry.
[61] C. Croce,et al. The FHIT Gene at 3p14.2 Is Abnormal in Lung Cancer , 1996, Cell.
[62] C. Croce,et al. The FHIT Gene, Spanning the Chromosome 3p14.2 Fragile Site and Renal Carcinoma–Associated t(3;8) Breakpoint, Is Abnormal in Digestive Tract Cancers , 1996, Cell.
[63] S. Ban,et al. Effect of radiation and cigarette smoking on expression of FUdR-inducible common fragile sites in human peripheral lymphocytes. , 1995, Mutation research.
[64] J. Testa,et al. Determination of the specificity of aphidicolin-induced breakage of the human 3p14.2 fragile site. , 1993, Genomics.
[65] P. Sparén,et al. Increasing incidence of both major histological types of esophageal carcinomas among men in Sweden , 1993, International journal of cancer.
[66] H. Aburatani,et al. Clinical and Genetic Studies of Renal Cell Carcinomas in a Family with a Constitutional Chromosome 3; 8 Translocation: Genetics of Familial Renal Carcinoma , 1993, Annals of Internal Medicine.
[67] S. Ljunghall,et al. Serum osteocalcin concentrations in patients with multiple myeloma — correlation with disease stage and survival , 1992, Journal of internal medicine.
[68] R. Espinosa,et al. Preferential integration of marker DNA into the chromosomal fragile site at 3p14: an approach to cloning fragile sites. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[69] T. Glover,et al. Chromosome breakage and recombination at fragile sites. , 1988, American journal of human genetics.
[70] C. Croce. Role of chromosome translocations in human neoplasia , 1987, Cell.
[71] J. Yunis,et al. Constitutive fragile sites and cancer. , 1984, Science.
[72] S. Jacobs,et al. Hereditary renal-cell carcinoma associated with a chromosomal translocation. , 1979, The New England journal of medicine.
[73] A. Knudson,et al. Mutation and childhood cancer: a probabilistic model for the incidence of retinoblastoma. , 1975, Proceedings of the National Academy of Sciences of the United States of America.
[74] A. Knudson. Mutation and cancer: statistical study of retinoblastoma. , 1971, Proceedings of the National Academy of Sciences of the United States of America.
[75] 富澤 由雄. Clinicopathological significance of fhit protein expression in stage 1 non-small cell lung carcinoma , 2001 .
[76] B. Agnarsson,et al. Alterations of the FHIT gene in breast cancer: association with tumor progression and patient survival. , 2001, Cancer detection and prevention.
[77] T. Enomoto,et al. FHIT alterations in cancerous and non‐cancerous cervical epithelium , 2000, International journal of cancer.
[78] C. Croce,et al. Muir-Torre-like syndrome in Fhit-deficient mice. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[79] Y. Pekarsky,et al. Role of FHIT in human cancer. , 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[80] G. Karpen,et al. Fragile sites in human chromosomes as regions of late-replicating DNA , 1987 .