Sensory clusters of toddlers with autism spectrum disorders: differences in affective symptoms.

BACKGROUND Individuals with autism spectrum disorders (ASDs) show variability in their sensory behaviors. In this study we identified clusters of toddlers with ASDs who shared sensory profiles and examined differences in affective symptoms across these clusters. METHOD Using cluster analysis 170 toddlers with ASDs were grouped based on parent rating of the Infant Toddler Sensory Profile (Dunn, 2002) under-responsivity, over-responsivity, and seeking scales. Affective symptoms were evaluated with the Infant Toddler Social Emotional Assessment (Carter & Briggs-Gowan, 2005). RESULTS Three clusters were identified: (1) low frequency of sensory symptoms (n = 44); (2) high frequency of symptoms (n = 49); and (3) mixed (n = 77); high frequency of under-and over-responsivity and low frequency of seeking). Relative to the low frequency cluster, parents rated toddlers in the high frequency and mixed clusters (both characterized by high frequencies of sensory under- and over-responsivity) as higher on negative emotionality, depression, and anxiety symptoms. Sensory and affective differences among clusters remained after co-varying severity of ASD symptoms. CONCLUSIONS Interdisciplinary assessments are recommended for toddlers with ASDs in order to identify the interplay of sensory and affective symptoms.

[1]  A. Azizian,et al.  Comparison of DSM-IV symptoms in elementary school-age children with PDD versus clinic and community samples , 2005, Autism : the international journal of research and practice.

[2]  C. Lord,et al.  Autism from 2 to 9 years of age. , 2006, Archives of general psychiatry.

[3]  P. Davies,et al.  Validating the diagnosis of sensory processing disorders using EEG technology. , 2007, The American journal of occupational therapy : official publication of the American Occupational Therapy Association.

[4]  A. Carter,et al.  Can we differentiate sensory over-responsivity from anxiety symptoms in toddlers? perspectives of occupational therapists and psychologists. , 2007, Infant mental health journal.

[5]  L. Miller,et al.  Concept evolution in sensory integration: a proposed nosology for diagnosis. , 2007, The American journal of occupational therapy : official publication of the American Occupational Therapy Association.

[6]  A. Couteur,et al.  Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders , 1994, Journal of autism and developmental disorders.

[7]  A. Aron,et al.  Sensory-processing sensitivity and its relation to introversion and emotionality. , 1997, Journal of personality and social psychology.

[8]  S. Hepburn,et al.  Parent Reports of Sensory Symptoms in Toddlers with Autism and Those with Other Developmental Disorders , 2003, Journal of autism and developmental disorders.

[9]  P. Howlin.  Outcomes in Autism Spectrum Disorders , 2005 .

[10]  J. H. Ward.  Hierarchical Grouping to Optimize an Objective Function , 1963 .

[11]  S. Rogers,et al.  Annotation: what do we know about sensory dysfunction in autism? A critical review of the empirical evidence. , 2005, Journal of child psychology and psychiatry, and allied disciplines.

[12]  S. Bradley-Johnson.  Mullen Scales of Early Learning , 1997 .

[13]  L. Miller,et al.  Children with disturbances in sensory processing: a pilot study examining the role of the parasympathetic nervous system. , 2003, The American journal of occupational therapy : official publication of the American Occupational Therapy Association.

[14]  Marcel Kinsbourne,et al.  Sensory and attention abnormalities in autistic spectrum disorders , 2006, Autism : the international journal of research and practice.

[15]  Ayres Aj,et al.  Hyper-responsivity to touch and vestibular stimuli as a predictor of positive response to sensory integration procedures by autistic children. , 1980 .

[16]  A. Couteur,et al.  Autism Diagnostic Interview Revised Manual , 2003 .

[17]  Brian Everitt,et al.  Cluster analysis , 1974 .

[18]  S. Bryson,et al.  The Prevalence of Anxiety and Mood Problems among Children with Autism and Asperger Syndrome , 2000 .

[19]  Sensory‐modulation disruption, electrodermal responses, and functional behaviors , 1999 .

[20]  Madhukar H. Trivedi,et al.  The pattern of sensory processing abnormalities in autism , 2006, Autism : the international journal of research and practice.

[21]  M. Kinsbourne.  Do Repetitive Movement Patterns in Children and Animals Serve a Dearousing Function? , 1980, Journal of developmental and behavioral pediatrics : JDBP.

[22]  Temple Grandin,et al.  Thinking in Pictures: And Other Reports From My Life With Autism , 1996 .

[23]  C. Corsello,et al.  Combining information from multiple sources in the diagnosis of autism spectrum disorders. , 2006, Journal of the American Academy of Child and Adolescent Psychiatry.

[24]  T. Grandin,et al.  Behavioral and physiological effects of deep pressure on children with autism: a pilot study evaluating the efficacy of Grandin's Hug Machine. , 1999, The American journal of occupational therapy : official publication of the American Occupational Therapy Association.

[25]  K. Stewart,et al.  Sensory integrative-based occupational therapy and functional outcomes in young children with pervasive developmental disorders: a single-subject study. , 1999, The American journal of occupational therapy : official publication of the American Occupational Therapy Association.

[26]  J. Kagan,et al.  Infant Predictors of Inhibited and Uninhibited Profiles , 1991 .

[27]  G. W. Milligan,et al.  An examination of procedures for determining the number of clusters in a data set , 1985 .

[28]  H. Goldsmith,et al.  A Population-Based Twin Study of Parentally Reported Tactile and Auditory Defensiveness in Young Children , 2006, Journal of abnormal child psychology.

[29]  W. Stone,et al.  Sensory Experiences Questionnaire: discriminating sensory features in young children with autism, developmental delays, and typical development. , 2006, Journal of child psychology and psychiatry, and allied disciplines.

[30]  J. Brian,et al.  Behavioral manifestations of autism in the first year of life , 2005, International Journal of Developmental Neuroscience.

[31]  W. Dunn.  The Impact of Sensory Processing Abilities on the Daily Lives of Young Children and Their Families: A Conceptual Model , 1997 .

[32]  A. Azizian,et al.  Psychiatric Symptoms in Preschool Children with PDD and Clinic and Comparison Samples , 2004, Journal of autism and developmental disorders.

[33]  Beth Pfeiffer,et al.  Sensory modulation and affective disorders in children and adolescents with Asperger's disorder. , 2005, The American journal of occupational therapy : official publication of the American Occupational Therapy Association.

[34]  Margaret J. Briggs-Gowan,et al.  Are infant-toddler social-emotional and behavioral problems transient? , 2006, Journal of the American Academy of Child and Adolescent Psychiatry.

[35]  M. Kinnealey,et al.  The relationship between sensory defensiveness, anxiety, depression and perception of pain in adults , 1999 .