A theoretical approach to select effective antisense oligodeoxyribonucleotides at high statistical probability.
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G Sczakiel | V. Patzel | G. Sczakiel | U. Steidl | R. Haas | R. Kronenwett | V Patzel | U Steidl | R Kronenwett | R Haas
[1] G. Sczakiel,et al. In vitro selection of fast-hybridizing and effective antisense RNAs directed against the human immunodeficiency virus type 1. , 1993, Nucleic acids research.
[2] H. Soreq,et al. Probing accessible sites for ribozymes on human acetylcholinesterase RNA. , 1997, RNA.
[3] W. James,et al. Computational approaches to the identification of ribozyme target sites. , 1997, Methods in molecular biology.
[4] O Ritter,et al. X-HUSAR, an X-based graphical interface for the analysis of genomic sequences. , 1995, Computer methods and programs in biomedicine.
[5] E. Jankowsky,et al. Efficient improvement of hammerhead ribozyme mediated cleavage of long substrates by oligonucleotide facilitators. , 1996, Biochemistry.
[6] P. Romby,et al. Implications of RNA structure on the annealing of a potent antisense RNA directed against the human immunodeficiency virus type 1. , 1997, Biochemistry.
[7] C. Bernstein,et al. β2 Integrin/ICAM Expression in Crohn's Disease☆ , 1998 .
[8] J. Voorhees,et al. Characterization of intercellular adhesion molecule-1 and HLA-DR expression in normal and inflamed skin: modulation by recombinant gamma interferon and tumor necrosis factor. , 1989, Journal of the American Academy of Dermatology.
[9] P. Schwille,et al. Quantitative hybridization kinetics of DNA probes to RNA in solution followed by diffusional fluorescence correlation analysis. , 1996, Biochemistry.
[10] C. Bennett,et al. Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides. , 1994, Journal of immunology.
[11] Michael Loran Dustin,et al. A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. , 1986, Journal of immunology.
[12] Randall R. Sakai,et al. Mapping of RNA accessible sites for antisense experiments with oligonucleotide libraries , 1998, Nature Biotechnology.
[13] K. Moelling,et al. Selective cleavage of bcr-abl chimeric RNAs by a ribozyme targeted to non-contiguous sequences. , 1994, Nucleic acids research.
[14] K. Stecker,et al. An ICAM-1 antisense oligonucleotide prevents and reverses dextran sulfate sodium-induced colitis in mice. , 1997, The Journal of pharmacology and experimental therapeutics.
[15] P. Schuster,et al. Statistics of RNA secondary structures , 1993, Biopolymers.
[16] Yedy Israel,et al. Tetranucleotide GGGA Motif in Primary RNA Transcripts , 1998, The Journal of Biological Chemistry.
[17] J. Tomassini,et al. cDNA cloning reveals that the major group rhinovirus receptor on HeLa cells is intercellular adhesion molecule 1. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[18] E. Southern,et al. Selecting effective antisense reagents on combinatorial oligonucleotide arrays , 1997, Nature Biotechnology.
[19] J. Rossi,et al. Rapid determination and quantitation of the accessibility to native RNAs by antisense oligodeoxynucleotides in murine cell extracts. , 1998, Nucleic acids research.
[20] D. Ecker,et al. Implication of RNA structure on antisense oligonucleotide hybridization kinetics. , 1992, Biochemistry.
[21] G Sczakiel,et al. Computer-aided search for effective antisense RNA target sequences of the human immunodeficiency virus type 1. , 1993, Antisense research and development.
[22] V. Patzel,et al. Theoretical design of antisense RNA structures substantially improves annealing kinetics and efficacy in human cells , 1998, Nature Biotechnology.
[23] H. Blöcker,et al. Predicting DNA duplex stability from the base sequence. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[24] O. Uhlenbeck. Tetraloops and RNA folding , 1990, Nature.
[25] Antisense ICAM-1 oligonucleotides block allograft rejection in rats. , 1997, Transplantation proceedings.
[26] Doriano Fabbro,et al. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase , 1996, Nature Medicine.
[27] W D Wilson,et al. Sequence specific thermodynamic and structural properties for DNA.RNA duplexes. , 1994, Biochemistry.
[28] S. Freier,et al. Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms. , 1991, The Journal of biological chemistry.
[29] R. Hanecak,et al. Combinatorial Screening and Rational Optimization for Hybridization to Folded Hepatitis C Virus RNA of Oligonucleotides with Biological Antisense Activity* , 1997, The Journal of Biological Chemistry.