Transcriptional regulation of human MUC4 gene: identification of a novel inhibitory element and its nuclear binding protein

[1]  Y. Miao,et al.  The increase in the expression and hypomethylation of MUC4 gene with the progression of pancreatic ductal adenocarcinoma , 2011, Medical oncology.

[2]  Y. Miao,et al.  Transcriptional regulation of human mucin gene MUC4 in pancreatic cancer cells , 2010, Molecular Biology Reports.

[3]  M. Goto,et al.  Promoter CpG methylation in cancer cells contributes to the regulation of MUC4 , 2009, British Journal of Cancer.

[4]  S. Peiró,et al.  IL-6 induces MUC4 expression through gp130/STAT3 pathway in gastric cancer cell lines. , 2008, Biochimica et biophysica acta.

[5]  I. van Seuningen,et al.  Epigenetic regulation of the human mucin gene MUC4 in epithelial cancer cell lines involves both DNA methylation and histone modifications mediated by DNA methyltransferases and histone deacetylases , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[6]  Si-Youn Song,et al.  Effect of Glucocorticoid on the MUC4 Gene in Nasal Polyps , 2007, The Laryngoscope.

[7]  S. Batra,et al.  IFN-γ-induced expression of MUC4 in pancreatic cancer cells is mediated by STAT-1 upregulation: a novel mechanism for IFN-γ response , 2007, Oncogene.

[8]  B. Hémon,et al.  Transcription factor AP-2alpha represses both the mucin MUC4 expression and pancreatic cancer cell proliferation. , 2007, Carcinogenesis.

[9]  I. van Seuningen,et al.  The Human Mucin MUC4 Is Transcriptionally Regulated by Caudal-related Homeobox, Hepatocyte Nuclear Factors, Forkhead Box A, and GATA Endodermal Transcription Factors in Epithelial Cancer Cells* , 2007, Journal of Biological Chemistry.

[10]  M. Copin,et al.  Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1alpha. , 2007, The Biochemical journal.

[11]  S. Batra,et al.  IFN-gamma-induced expression of MUC4 in pancreatic cancer cells is mediated by STAT-1 upregulation: a novel mechanism for IFN-gamma response. , 2007, Oncogene.

[12]  I. van Seuningen,et al.  The antagonistic regulation of human MUC4 and ErbB-2 genes by the Ets protein PEA3 in pancreatic cancer cells: implications for the proliferation/differentiation balance in the cells. , 2005, The Biochemical journal.

[13]  M. Bucan,et al.  Promoter features related to tissue specificity as measured by Shannon entropy , 2005, Genome Biology.

[14]  M. Atchison,et al.  YY1 DNA binding and PcG recruitment requires CtBP. , 2004, Genes & development.

[15]  S. Grossman,et al.  Yin Yang 1 Is a Negative Regulator of p53 , 2004, Cell.

[16]  J. Meza,et al.  Inhibition of MUC4 Expression Suppresses Pancreatic Tumor Cell Growth and Metastasis , 2004, Cancer Research.

[17]  Christine A Iacobuzio-Donahue,et al.  Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies. , 2003, Cancer research.

[18]  J. Cameron,et al.  MUC4 expression increases progressively in pancreatic intraepithelial neoplasia. , 2002, American journal of clinical pathology.

[19]  H. Friess,et al.  Mucin (MUC) gene expression in human pancreatic adenocarcinoma and chronic pancreatitis: a potential role of MUC4 as a tumor marker of diagnostic significance. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[20]  I. van Seuningen,et al.  Characterization of human mucin gene MUC4 promoter: importance of growth factors and proinflammatory cytokines for its regulation in pancreatic cancer cells. , 2001, The Journal of biological chemistry.

[21]  E. Seto,et al.  Unlocking the mechanisms of transcription factor YY1: are chromatin modifying enzymes the key? , 1999, Gene.

[22]  Jeng-Shin Lee,et al.  Everything you have ever wanted to know about Yin Yang 1...... , 1997, Biochimica et biophysica acta.

[23]  Wen‐Ming Yang,et al.  Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[24]  Thomas Shenk,et al.  Interaction between transcription factors Spl and YY1 , 1993, Nature.

[25]  Yang Shi,et al.  Transcriptional repression by YY1, a human GLI-Krüippel-related protein, and relief of repression by adenovirus E1A protein , 1991, Cell.

[26]  M. Gross,et al.  Molecular cloning and chromosomal localization of a novel human tracheo-bronchial mucin cDNA containing tandemly repeated sequences of 48 base pairs. , 1991, Biochemical and biophysical research communications.