Review of PINK1-Parkin-mediated mitochondrial autophagy in Alzheimer's disease.
暂无分享,去创建一个
[1] A. Jekabsone,et al. The Role of Intracellular Ca2+ and Mitochondrial ROS in Small Aβ1-42 Oligomer-Induced Microglial Death , 2023, International journal of molecular sciences.
[2] Tao Li,et al. Inhibition of VDAC1 Rescues Aβ1-42-Induced Mitochondrial Dysfunction and Ferroptosis via Activation of AMPK and Wnt/β-Catenin Pathways , 2023, Mediators of inflammation.
[3] N. Vardi,et al. Targeting the overexpressed mitochondrial protein VDAC1 in a mouse model of Alzheimer’s disease protects against mitochondrial dysfunction and mitigates brain pathology , 2022, Translational Neurodegeneration.
[4] A. Morsy,et al. Functionalized Allopurinols Targeting Amyloid-Binding Alcohol Dehydrogenase Rescue Aβ-Induced Mitochondrial Dysfunction. , 2022, ACS chemical neuroscience.
[5] K. Dev,et al. Mechanistic and therapeutic role of Drp1 in the pathogenesis of Alzheimer's disease , 2022, The European journal of neuroscience.
[6] P. Liu,et al. PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer’s disease , 2021, Acta Pharmacologica Sinica.
[7] O. El-Deeb,et al. The Correlation Between PINK-1/Parkin Mediated Mitophagy, Endoplasmic Reticulum Stress and Total Polyamines in Pediatric Bronchial Asthma: An Integrated Network of Pathways , 2021, Molecular biology reports.
[8] Xifei Yang,et al. Melatonin ameliorates cognitive deficits through improving mitophagy in a mouse model of Alzheimer’s disease , 2021, Journal of pineal research.
[9] F. Roberts,et al. New Insights into Molecular Mechanisms Mediating Adaptation to Exercise; A Review Focusing on Mitochondrial Biogenesis, Mitochondrial Function, Mitophagy and Autophagy , 2021, Cells.
[10] B. Maček,et al. Regulation of mitochondrial cargo-selective autophagy by posttranslational modifications , 2021, The Journal of biological chemistry.
[11] Shinn-Zong Lin,et al. Peiminine Reduces ARTS-Mediated Degradation of XIAP by Modulating the PINK1/Parkin Pathway to Ameliorate 6-Hydroxydopamine Toxicity and α-Synuclein Accumulation in Parkinson’s Disease Models In Vivo and In Vitro , 2021, International journal of molecular sciences.
[12] M. Karbowski,et al. The OMM-severed and IMM-ubiquitinated mitochondria are intermediates of mitochondrial proteotoxicity-induced autophagy in PRKN/parkin-deficient cells , 2021, Autophagy.
[13] Shiyu Jin,et al. Activation of GPR55 attenuates cognitive impairment and neurotoxicity in a mouse model of Alzheimer's disease induced by Aβ1–42 through inhibiting RhoA/ROCK2 pathway , 2021, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[14] C. Hölscher,et al. A GLP-1/GIP Dual Receptor Agonist DA4-JC Effectively Attenuates Cognitive Impairment and Pathology in the APP/PS1/Tau Model of Alzheimer's Disease. , 2021, Journal of Alzheimer's disease : JAD.
[15] Feifei Feng,et al. Defective Autophagy and Mitophagy in Alzheimer’s Disease: Mechanisms and Translational Implications , 2021, Molecular Neurobiology.
[16] Shuaifeng Yang,et al. Research Progress on the Mechanism of Mitochondrial Autophagy in Cerebral Stroke , 2021, Frontiers in Aging Neuroscience.
[17] Yan Huang,et al. Caveolin-1 attenuates acetaminophen aggravated lipid accumulation in alcoholic fatty liver by activating mitophagy via the Pink-1/Parkin pathway. , 2021, European journal of pharmacology.
[18] Zhuo Yang,et al. Rapamycin activates mitophagy and alleviates cognitive and synaptic plasticity deficits in a mouse model of Alzheimer's disease. , 2021, The journals of gerontology. Series A, Biological sciences and medical sciences.
[19] M. F. Ferrari,et al. Parkin is downregulated among autophagy-related proteins prior to hyperphosphorylation of Tau in TS65DN mice. , 2021, Biochemical and biophysical research communications.
[20] B. Albensi,et al. Alzheimer’s Disease Pathogenesis: Role of Autophagy and Mitophagy Focusing in Microglia , 2021, International journal of molecular sciences.
[21] M. Hamrick,et al. Targeting the Mitochondrial Permeability Transition Pore to Prevent Age-Associated Cell Damage and Neurodegeneration , 2021, Oxidative medicine and cellular longevity.
[22] J. Homola,et al. Ionic Environment Affects Biomolecular Interactions of Amyloid-β: SPR Biosensor Study , 2020, International journal of molecular sciences.
[23] P. Moreira,et al. PINK1/PARKIN signalling in neurodegeneration and neuroinflammation , 2020, Acta neuropathologica communications.
[24] Dong Gil Lee,et al. Amyloid-beta oligomers induce Parkin-mediated mitophagy by reducing Miro1. , 2020, The Biochemical journal.
[25] P. Reddy,et al. Defective mitophagy in Alzheimer’s disease , 2020, Ageing Research Reviews.
[26] M. Ejma,et al. The Links between Parkinson’s Disease and Cancer , 2020, Biomedicines.
[27] Li Tang,et al. Study of mitophagy and ATP-related metabolomics based on β-amyloid levels in Alzheimer's disease. , 2020, Experimental cell research.
[28] J. Homola,et al. Study of Biomolecular Interactions of Mitochondrial Proteins Related to Alzheimer’s Disease: Toward Multi-Interaction Biomolecular Processes , 2020, Biomolecules.
[29] Chong Wang,et al. PINK1: The guard of mitochondria. , 2020, Life sciences.
[30] Lifen Xie,et al. Berberine alleviates cisplatin-induced acute kidney injury by regulating mitophagy via PINK 1/Parkin pathway , 2020, Translational andrology and urology.
[31] Jun Ren,et al. ALDH2 contributes to melatonin-induced protection against APP/PS1 mutation-prompted cardiac anomalies through cGAS-STING-TBK1-mediated regulation of mitophagy , 2020, Signal Transduction and Targeted Therapy.
[32] Yongqi Fang,et al. β-Asarone improves learning and memory in Aβ1-42-induced Alzheimer’s disease rats by regulating PINK1-Parkin-mediated mitophagy , 2020, Metabolic Brain Disease.
[33] Ray-Jade Chen,et al. Induction of Autophagy by Vasicinone Protects Neural Cells from Mitochondrial Dysfunction and Attenuates Paraquat-Mediated Parkinson’s Disease Associated α-Synuclein Levels , 2020, Nutrients.
[34] Carola Tapia-Monsalves,et al. The Role of Mitochondrial Impairment in Alzheimer´s Disease Neurodegeneration: The Tau Connection , 2020, Current neuropharmacology.
[35] Yan Yuan,et al. Cadmium induces mitophagy via AMP‐activated protein kinases activation in a PINK1/Parkin‐dependent manner in PC12 cells , 2020, Cell proliferation.
[36] Lan Zhang,et al. Tetrahydroxy stilbene glycoside alleviated inflammatory damage by mitophagy via AMPK related PINK1/Parkin signaling pathway. , 2020, Biochemical pharmacology.
[37] Yuxuan Guo,et al. Astaxanthin Attenuates Hypertensive Vascular Remodeling by Protecting Vascular Smooth Muscle Cells from Oxidative Stress-Induced Mitochondrial Dysfunction , 2020, Oxidative medicine and cellular longevity.
[38] M. Brini,et al. PINK1/Parkin Mediated Mitophagy, Ca2+ Signalling, and ER–Mitochondria Contacts in Parkinson’s Disease , 2020, International journal of molecular sciences.
[39] Qiang Shi,et al. Enhanced mitophagy activity in prion infected cultured cells and prion infected experimental mice via Pink1/Parkin dependent mitophagy pathway. , 2020, ACS chemical neuroscience.
[40] Junbo Xie,et al. 6‴-Feruloylspinosin alleviated beta-amyloid induced toxicity by promoting mitophagy in Caenorhabditis elegans (GMC101) and PC12 cells. , 2020, The Science of the total environment.
[41] Ting Zhang,et al. Parkin overexpression attenuates Aβ-induced mitochondrial dysfunction in HEK293 cells by restoring impaired mitophagy. , 2020, Life sciences.
[42] Tomotake Kanki,et al. Regulatory Mechanisms of Mitochondrial Autophagy: Lessons From Yeast , 2019, Front. Plant Sci..
[43] B. Imbimbo,et al. Investigational BACE inhibitors for the treatment of Alzheimer’s disease , 2019, Expert opinion on investigational drugs.
[44] Terry K. Smith,et al. Novel Benzothiazole-Based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer’s Disease Treatment , 2019, Molecules.
[45] R. Nixon,et al. mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome formation, and mitophagy , 2019, Cell Death & Disease.
[46] S. Noggle,et al. Autophagy Induction by Bexarotene Promotes Mitophagy in Presenilin 1 Familial Alzheimer’s Disease iPSC-Derived Neural Stem Cells , 2019, Molecular Neurobiology.
[47] Xinhong Zhu,et al. ABAD/17β-HSD10 reduction contributes to the protective mechanism of huperzine a on the cerebral mitochondrial function in APP/PS1 mice , 2019, Neurobiology of Aging.
[48] R. Swerdlow,et al. Mitochondrial dysfunction in Alzheimer's disease: Role in pathogenesis and novel therapeutic opportunities , 2019, British journal of pharmacology.
[49] Huiya Huang,et al. CoQ10 ameliorates mitochondrial dysfunction in diabetic nephropathy through mitophagy. , 2019, The Journal of endocrinology.
[50] M. Z. Cader,et al. Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease , 2019, Nature Neuroscience.
[51] C. Chu. Mechanisms of selective autophagy and mitophagy: Implications for neurodegenerative diseases , 2019, Neurobiology of Disease.
[52] Qinwen Wang,et al. Disrupted‐in‐schizophrenia‐1 protects synaptic plasticity in a transgenic mouse model of Alzheimer’s disease as a mitophagy receptor , 2018, Aging cell.
[53] Yuqiang Wang,et al. Hippocampal Proteomic Alteration in Triple Transgenic Mouse Model of Alzheimer's Disease and Implication of PINK 1 Regulation in Donepezil Treatment. , 2018, Journal of proteome research.
[54] A. Morsy,et al. Amyloid-Binding Alcohol Dehydrogenase (ABAD) Inhibitors for the Treatment of Alzheimer's Disease. , 2018, Journal of medicinal chemistry.
[55] D. Sabatini,et al. RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway , 2018, Science Advances.
[56] Jian Cao,et al. RETRACTED ARTICLE: Matrine promotes liver cancer cell apoptosis by inhibiting mitophagy and PINK1/Parkin pathways , 2018, Cell Stress and Chaperones.
[57] C. Leeuwenburgh,et al. Mitochondrial quality control mechanisms as molecular targets in cardiac ageing , 2018, Nature Reviews Cardiology.
[58] S. Barnes,et al. Methods for assessing mitochondrial quality control mechanisms and cellular consequences in cell culture , 2018, Redox biology.
[59] E. Pardon,et al. Structure of PINK1 in complex with its substrate ubiquitin , 2017, Nature.
[60] K. Lim,et al. Parkin‐independent mitophagy—FKBP8 takes the stage , 2017, EMBO reports.
[61] Doo Sin Jo,et al. Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model , 2017, The Journal of Neuroscience.
[62] T. Goiran,et al. β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog–Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models , 2017, Biological Psychiatry.
[63] Lin Sun,et al. The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1 , 2016, Redox biology.
[64] Ramesh Kandimalla,et al. Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease. , 2016, Human molecular genetics.
[65] E. Ziviani,et al. Counteracting PINK/Parkin Deficiency in the Activation of Mitophagy: A Potential Therapeutic Intervention for Parkinson’s Disease , 2016, Current neuropharmacology.
[66] John Seibyl,et al. Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial. , 2015, JAMA neurology.
[67] H. Soininen,et al. Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome , 2013, Progress in Neurobiology.
[68] P. Reddy,et al. Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease. , 2012, Human molecular genetics.
[69] L. Pallanck,et al. Neurodegenerative disease: Pink, parkin and the brain , 2006, Nature.