A Case Of Disseminated Histoplasmosis In An Immunocompetent Individual

Histoplasmosis has a wide spectrum of manifestations ranging from asymptomatic infection to systemic dissemination, depending on the intensity of exposure and immune status of the exposed individual. We report a case of disseminated histoplasmosis in a 57 year old male from a non endemic area, who had fever, lymphadenopathy, multiple subcutaneous swellings and bilateral adrenal lesions at presentation. Diagnosis was made by demonstrating Histoplasma in the culture of lymph node aspirate. But no features of underlying immunodeficiency could be found in this individual even after an extensive search. Patient was successfully treated with Amphotericin B and Itraconazole.