Full-range, high-speed, high-resolution 1 μm spectral-domain optical coherence tomography with BM-scan method for the human posterior eye imaging

High-speed, high-resolution full-range 1 μm spectral-domain optical coherence tomography has been demonstrated. The axial resolution of 7 μm and the depth range of 2.6 mm in tissue are achieved with the line rate of 46,900 Hz. The sensitivity of 98 dB is obtained with full-range imaging. These parameters are comparable or superior than those of commercially available ophthalmic instruments. Three dimensional structures of the retina and the choroid are visualized with the high axial resolution. High penetration property of 1 μm wavelength band in the deeper region of the posterior human eye enable high-contrast imaging of the choroid. In addition to that, vessels outer the choroid are visualized.

[1]  Ruikang K. Wang In vivo full range complex Fourier domain optical coherence tomography , 2007 .

[2]  S. Yun,et al.  High-speed spectral-domain optical coherence tomography at 1.3 mum wavelength. , 2003, Optics express.

[3]  R. Leitgeb,et al.  High speed full range complex spectral domain optical coherence tomography. , 2005, Optics express.

[4]  A. Fercher,et al.  Full range complex spectral optical coherence tomography technique in eye imaging. , 2002, Optics letters.

[5]  J. Duker,et al.  Three-dimensional retinal imaging with high-speed ultrahigh-resolution optical coherence tomography. , 2005, Ophthalmology.

[6]  T. Yatagai,et al.  Simultaneous B-M-mode scanning method for real-time full-range Fourier domain optical coherence tomography. , 2006, Applied Optics.

[7]  A. Fercher,et al.  Phase-shifting algorithm to achieve high-speed long-depth-range probing by frequency-domain optical coherence tomography. , 2003, Optics letters.

[8]  Dietrich Schweitzer,et al.  Optical properties of ocular fundus tissues determined by optical coherence tomography , 2000 .

[9]  W. Drexler,et al.  Three-dimensional optical coherence tomography at 1050 nm versus 800 nm in retinal pathologies: enhanced performance and choroidal penetration in cataract patients. , 2007, Journal of biomedical optics.

[10]  Teresa C. Chen,et al.  In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography. , 2004, Optics letters.

[11]  W. Drexler,et al.  In vivo retinal optical coherence tomography at 1040 nm - enhanced penetration into the choroid. , 2005, Optics express.