Progress towards a consensus on biomarkers for Alzheimer's disease: a review of peripheral analytes.
暂无分享,去创建一个
Blaine R. Roberts | James D Doecke | Colin L Masters | Alan Rembach | C. Masters | A. Rembach | T. Ryan | J. Doecke | B. Roberts | W. Wilson | K. Barnham | Kevin J Barnham | Tim M Ryan | Blaine R Roberts | William J Wilson | Andrew D Watt | A. Watt | William J. Wilson
[1] C. Hong,et al. Peripheral Cytokines and Chemokines in Alzheimer’s Disease , 2009, Dementia and Geriatric Cognitive Disorders.
[2] L. Minthon,et al. No Diagnostic Value of Plasma Clusterin in Alzheimer's Disease , 2012, PloS one.
[3] P. Pasqualetti,et al. Excess of nonceruloplasmin serum copper in AD correlates with MMSE, CSF β-amyloid, and h-tau , 2006, Neurology.
[4] C. Masters,et al. Variability in blood-based amyloid-beta assays: the need for consensus on pre-analytical processing. , 2012, Journal of Alzheimer's disease : JAD.
[5] P. Rossini,et al. Alteration of peripheral markers of copper homeostasis in Alzheimer's disease patients: implications in aetiology and therapy. , 2007, The journal of nutrition, health & aging.
[6] S. Tsuji,et al. The beta APP717 Alzheimer mutation increases the percentage of plasma amyloid-beta protein ending at A beta 42(43) , 1997, Neurology.
[7] B. Hyman,et al. Plasma Amyloid and the Risk of Alzheimer Disease and Dementia in Elderly Men , 2008 .
[8] D. Holtzman,et al. Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease , 2008, Nature.
[9] J. Thome,et al. Proteomic research in psychiatry , 2011, Journal of psychopharmacology.
[10] F. Jessen,et al. Amyloid β peptides in plasma in early diagnosis of Alzheimer's disease: A multicenter study with multiplexing , 2010, Experimental Neurology.
[11] Deborah Pinchev,et al. Mining biomarkers in human sera using proteomic tools , 2004, Proteomics.
[12] E. Oguni,et al. Amyloid β protein in plasma from patients with sporadic Alzheimer's disease , 1996, Journal of the Neurological Sciences.
[13] Tracy R. Keeney,et al. From SOMAmer-Based Biomarker Discovery to Diagnostic and Clinical Applications: A SOMAmer-Based, Streamlined Multiplex Proteomic Assay , 2011, PloS one.
[14] T. Lehtimäki,et al. Apolipoprotein E (apoE) polymorphism and its influence on ApoE concentrations in the cerebrospinal fluid in Finnish patients with Alzheimer's disease , 2004, Human Genetics.
[15] Patrick L. McGeer,et al. Inflammatory processes in Alzheimer's disease , 2003, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[16] F. Jiménez-Jiménez,et al. Cerebrospinal fluid levels of transition metals in patients with Alzheimer's disease , 1998, Journal of Neural Transmission.
[17] W. Thies,et al. 2008 Alzheimer’s disease facts and figures , 2008, Alzheimer's & Dementia.
[18] N. Robakis,et al. Increased Expression but Reduced Activity of Antioxidant Enzymes in Alzheimer's Disease. , 1999, Journal of Alzheimer's disease : JAD.
[19] C. Masters,et al. Overexpression of Alzheimer's Disease Amyloid-β Opposes the Age-dependent Elevations of Brain Copper and Iron* , 2002, The Journal of Biological Chemistry.
[20] V. Haroutunian,et al. Elevated cortical zinc in Alzheimer disease , 2006, Neurology.
[21] T. Miida,et al. [Lipoproteins and their receptors in the central nervous system]. , 2009, Rinsho byori. The Japanese journal of clinical pathology.
[22] K. Yaffe,et al. The projected effect of risk factor reduction on Alzheimer's disease prevalence , 2011, The Lancet Neurology.
[23] C. Rowe,et al. Plasma amyloid-beta as a biomarker in Alzheimer's disease: the AIBL study of aging. , 2010, Journal of Alzheimer's disease : JAD.
[24] Peripheral Mitochondrial Dysfunction in Alzheimer’s Disease: Focus on Lymphocytes , 2012, Molecular Neurobiology.
[25] J. Eaton,et al. Hemoglobin. A biologic fenton reagent. , 1984, The Journal of biological chemistry.
[26] P. Mcgeer,et al. Thrombin accumulation in brains of patients with Alzheimer's disease , 1992, Neuroscience Letters.
[27] D. Selkoe,et al. Alzheimer's Disease: A Central Role for Amyloid , 1994, Journal of neuropathology and experimental neurology.
[28] Justin Bedo,et al. Blood-based protein biomarkers for diagnosis of Alzheimer disease. , 2012, Archives of neurology.
[29] R. W. Gracy,et al. Identification of oxidized plasma proteins in Alzheimer's disease. , 2002, Biochemical and biophysical research communications.
[30] N. Inestrosa,et al. Postsynaptic Receptors for Amyloid-β Oligomers as Mediators of Neuronal Damage in Alzheimer’s Disease , 2012, Front. Physio..
[31] T. Berzin,et al. Microvascular injury and blood–brain barrier leakage in Alzheimer's disease , 2007, Neurobiology of Aging.
[32] Guanghua Xiao,et al. A Blood-Based Screening Tool for Alzheimer's Disease That Spans Serum and Plasma: Findings from TARC and ADNI , 2011, PloS one.
[33] A. Fagan,et al. Cerebrospinal fluid tau and ptau181 increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer's disease , 2009, EMBO molecular medicine.
[34] L. Kiemeney,et al. Corrigendum: Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer , 2009, Nature Genetics.
[35] P. Pasqualetti,et al. Copper in Alzheimer's disease: a meta-analysis of serum,plasma, and cerebrospinal fluid studies. , 2011, Journal of Alzheimer's disease : JAD.
[36] R. Mayeux,et al. APOE genotype, plasma lipids, lipoproteins, and AD in community elderly , 1999, Neurology.
[37] B. Hyman,et al. APOE ε3/ε4 heterozygotes have an elevated proportion of apolipoprotein E4 in cerebrospinal fluid relative to plasma, independent of Alzheimer’s disease diagnosis , 2003, Experimental Neurology.
[38] A. Nicholson,et al. Neutrophil/lymphocyte ratio and its association with survival after complete resection in non-small cell lung cancer. , 2009, The Journal of thoracic and cardiovascular surgery.
[39] J. Growdon,et al. Evidence for a membrane defect in Alzheimer disease brain. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[40] M. Weiner,et al. Cerebrospinal fluid and plasma biomarkers in Alzheimer disease , 2010, Nature Reviews Neurology.
[41] Nick C Fox,et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease, and shows evidence for additional susceptibility genes , 2009, Nature Genetics.
[42] P. Pasqualetti,et al. Excess of serum copper not related to ceruloplasmin in Alzheimer disease , 2005, Neurology.
[43] G. Rebeck,et al. Regulated Proteolysis of APP and ApoE Receptors , 2008, Molecular Neurobiology.
[44] P. Pasqualetti,et al. Elevation of serum copper levels discriminates Alzheimer’s disease from vascular dementia , 2003, Neurology.
[45] S. Kang,et al. Nuclear clusterin is associated with neuronal apoptosis in the developing rat brain upon ethanol exposure. , 2012, Alcoholism, clinical and experimental research.
[46] A. Thomson,et al. Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease. , 2008, Biochemical Society transactions.
[47] Qian-Li Xue,et al. Twenty-six-year change in total cholesterol levels and incident dementia: the Honolulu-Asia Aging Study. , 2007, Archives of neurology.
[48] J. Growdon,et al. Age but Not Diagnosis Is the Main Predictor of Plasma Amyloid β-Protein Levels , 2003 .
[49] C. Mariani,et al. Plasma levels of beta-amyloid (1–42) in Alzheimer's disease and mild cognitive impairment , 2006, Neurobiology of Aging.
[50] B. Sedighi,et al. A study of serum copper and ceruloplasmin in Alzheimer's disease in Kerman, Iran , 2006 .
[51] Sudha Seshadri,et al. Plasma total cholesterol level as a risk factor for Alzheimer disease: the Framingham Study. , 2003, Archives of internal medicine.
[52] C. Rowe,et al. Increasing the predictive accuracy of amyloid-β blood-borne biomarkers in Alzheimer's disease. , 2011, Journal of Alzheimer's disease : JAD.
[53] D. Butterfield,et al. Peptides and proteins in plasma and cerebrospinal fluid as biomarkers for the prediction, diagnosis, and monitoring of therapeutic efficacy of Alzheimer's disease. , 2008, Biochimica et biophysica acta.
[54] V. Papadopoulos,et al. Oxidative stress-mediated DHEA formation in Alzheimer’s disease pathology , 2003, Neurobiology of Aging.
[55] J. Gutteridge,et al. The antioxidant activity of haptoglobin towards haemoglobin-stimulated lipid peroxidation. , 1987, Biochimica et biophysica acta.
[56] Michael I. Miller,et al. Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss , 2010, Alzheimer's & Dementia.
[57] M. Mattson,et al. Aβ25–35 induces rapid lysis of red blood cells: contrast with Aβ1–42 and examination of underlying mechanisms , 1997, Brain Research.
[58] K. Blennow,et al. Altered Distribution of the Gangliosides GM1 and GM2 in Alzheimer’s Disease , 2012, Dementia and Geriatric Cognitive Disorders.
[59] P. He,et al. Plasma metabolic profiling of Alzheimer's disease by liquid chromatography/mass spectrometry. , 2010, Clinical biochemistry.
[60] L. Buée,et al. Association of plasma amyloid β with risk of dementia , 2009, Neurology.
[61] P. Rossini,et al. Ceruloplasmin fragmentation is implicated in 'free' copper deregulation of Alzheimer disease , 2008, Prion.
[62] D. Selkoe,et al. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide , 2007, Nature Reviews Molecular Cell Biology.
[63] K. Dross,et al. Concentration and origin of choline in the rat brain , 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.
[64] J. Benito-León,et al. Cerebrospinal fluid levels of non-neurotransmitter amino acids in patients with Alzheimer's disease , 1998, Journal of Neural Transmission.
[65] P. Ince,et al. Mitochondrial enzyme-deficient hippocampal neurons and choroidal cells in AD , 2001, Neurology.
[66] S. Lovestone,et al. Proteome-based plasma biomarkers for Alzheimer's disease. , 2006, Brain : a journal of neurology.
[67] Colin L Masters,et al. Gene knockout of amyloid precursor protein and amyloid precursor‐like protein‐2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts , 2004, Journal of neurochemistry.
[68] M. Muckenthaler,et al. Altered serum iron and copper homeostasis predicts cognitive decline in mild cognitive impairment. , 2012, Journal of Alzheimer's disease : JAD.
[69] M. Pras,et al. Apolipoprotein E Carboxyl-terminal Fragments Are Complexed to Amyloids A and L , 1995, The Journal of Biological Chemistry.
[70] M. Sabbagh,et al. Potential Peripheral Biomarkers for the Diagnosis of Alzheimer's Disease , 2011, International journal of Alzheimer's disease.
[71] Tamara B Harris,et al. Association of plasma beta-amyloid level and cognitive reserve with subsequent cognitive decline. , 2011, JAMA.
[72] T. Yagi,et al. Cadherin-related Neuronal Receptors in Incisor Development , 2003, Journal of dental research.
[73] P. Scheltens,et al. Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS–ADRDA criteria , 2007, The Lancet Neurology.
[74] K. Blennow,et al. Standardization of measurement of β-amyloid(1-42) in cerebrospinal fluid and plasma , 2000, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.
[75] L. Pike. The challenge of lipid rafts This work was supported by National Institutes of Health grants RO1 GM064491 and R01 GM082824 to LJP. Published, JLR Papers in Press, October 27, 2008. , 2009, Journal of Lipid Research.
[76] Xianlin Han,et al. Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis , 2002, Journal of neurochemistry.
[77] C. Masters,et al. Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice , 1999, Brain Research.
[78] G. Jicha,et al. Blood serum miRNA: Non-invasive biomarkers for Alzheimer's disease , 2012, Experimental Neurology.
[79] C. Laske,et al. Amyloid-β peptides in plasma and cognitive decline after 1 year follow-up in Alzheimer's disease patients. , 2010, Journal of Alzheimer's disease : JAD.
[80] J. Growdon,et al. Plasma F2A Isoprostane Levels in Alzheimer’s and Parkinson’s Disease , 2007, Neurodegenerative Diseases.
[81] J. Escanero,et al. Serum aluminum levels in alzheimer’s disease and other senile dementias , 2007, Biological Trace Element Research.
[82] R. Mayeux,et al. Plasma A&bgr;40 and A&bgr;42 and Alzheimer’s disease: Relation to age, mortality, and risk , 2003 .
[83] H. Möller,et al. A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients , 2000, Neurobiology of Aging.
[84] J. Trojanowski,et al. Increased 8,12‐iso‐iPF2α‐VI in Alzheimer's disease: Correlation of a noninvasive index of lipid peroxidation with disease severity , 2000, Annals of neurology.
[85] E. B. Larson,et al. Serum cholesterol and risk of Alzheimer disease , 2005, Neurology.
[86] P. Moscato,et al. Differences in Abundances of Cell-Signalling Proteins in Blood Reveal Novel Biomarkers for Early Detection Of Clinical Alzheimer's Disease , 2011, PloS one.
[87] Antonio Lanzirotti,et al. Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with beta-amyloid deposits in Alzheimer's disease. , 2006, Journal of structural biology.
[88] R. Mayeux,et al. Change in plasma Aβ peptides and onset of dementia in adults with Down syndrome , 2010, Neurology.
[89] M. Muckenthaler,et al. Iron toxicity in diseases of aging: Alzheimer's disease, Parkinson's disease and atherosclerosis. , 2009, Journal of Alzheimer's disease : JAD.
[90] B. Winblad,et al. Abnormal platelet amyloid-β protein precursor (AβPP) metabolism in Alzheimer's disease: identification and characterization of a new AβPP isoform as potential biomarker. , 2013, Journal of Alzheimer's disease : JAD.
[91] A. Fagan,et al. Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research , 2015, Alzheimer's & Dementia.
[92] P. Sachdev,et al. Plasma biomarkers for mild cognitive impairment and Alzheimer's disease , 2009, Brain Research Reviews.
[93] R. Kalaria,et al. Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease. , 1993, The American journal of pathology.
[94] G. Kemmler,et al. Plasma amyloid β protein 42 in non-demented persons aged 75 years: Effects of concomitant medication and medial temporal lobe atrophy , 2005, Neurobiology of Aging.
[95] C. Lyketsos,et al. Serum ceramides increase the risk of Alzheimer disease , 2012, Neurology.
[96] C. Jack,et al. Factors affecting Aβ plasma levels and their utility as biomarkers in ADNI , 2011, Acta Neuropathologica.
[97] Nick C Fox,et al. Letter abstract - Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's Disease , 2009 .
[98] K. Blennow,et al. Evolution of Aβ42 and Aβ40 levels and Aβ42/Aβ40 ratio in plasma during progression of Alzheimer’s disease: A multicenter assessment , 2009 .
[99] N. Inestrosa,et al. Platelets Are the Primary Source of Amyloid β-Peptide in Human Blood , 1995 .
[100] I. Kloszewska,et al. Plasma levels of alpha beta peptides are altered in amnestic mild cognitive impairment but not in sporadic Alzheimer's disease. , 2005, Acta neurobiologiae experimentalis.
[101] I. Björkhem,et al. Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain , 2006, Journal of internal medicine.
[102] Xianlin Han,et al. Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics , 2011, PloS one.
[103] K. Blennow,et al. Inflammatory Markers in Matched Plasma and Cerebrospinal Fluid from Patients with Alzheimer’s Disease , 2003, Dementia and Geriatric Cognitive Disorders.
[104] P. Grammas,et al. Thrombin, a mediator of neurotoxicity and memory impairment , 2004, Neurobiology of Aging.
[105] R. Wyatt,et al. Cerebrospinal fluid protein variations in common to Alzheimer's disease and schizophrenia. , 1992, Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society.
[106] A. Hofman,et al. Plasma Aβ1–40 and Aβ1–42 and the risk of dementia: a prospective case-cohort study , 2006, The Lancet Neurology.
[107] C. Masters,et al. Inhibition of γ‐secretase causes increased secretion of amyloid precursor protein C‐terminal fragments in association with exosomes , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[108] R. Petersen,et al. Association of Low Plasma Aβ42/Aβ40 Ratios With Increased Imminent Risk for Mild Cognitive Impairment and Alzheimer Disease , 2007 .
[109] P. Panegyres,et al. Genetic testing for Alzheimer's disease , 2000, The Medical journal of Australia.
[110] Solve Sæbø,et al. A gene expression pattern in blood for the early detection of Alzheimer's disease. , 2011, Journal of Alzheimer's disease : JAD.
[111] G. Schellenberg,et al. Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease , 1996, Nature Medicine.
[112] Tony Wyss-Coray,et al. Inflammation in Neurodegenerative Disease—A Double-Edged Sword , 2002, Neuron.
[113] S. Lovestone,et al. Plasma biomarkers for Alzheimer's disease: much needed but tough to find. , 2012, Biomarkers in medicine.
[114] Pedro Pesini,et al. Reliable Measurements of the β-Amyloid Pool in Blood Could Help in the Early Diagnosis of AD , 2012, International journal of Alzheimer's disease.
[115] B. Festoff,et al. Serine proteases and their serpin inhibitors in Alzheimer's disease. , 1994, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[116] P. Mehta,et al. Amyloid β protein 1–40 and 1–42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer disease , 2001, Neuroscience Letters.
[117] D. Galimberti,et al. Immunotherapy against amyloid pathology in Alzheimer's disease , 2013, Journal of the Neurological Sciences.
[118] Colin L Masters,et al. Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics , 2006, Journal of neurochemistry.
[119] Klaus Fassbender,et al. Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients , 2004, Neurobiology of Aging.
[120] M. Tolar,et al. Neurotoxicity of the 22 kDa Thrombin-Cleavage Fragment of Apolipoprotein E and Related Synthetic Peptides Is Receptor-Mediated , 1997, The Journal of Neuroscience.
[121] G. Ricevuti,et al. Alzheimer disease and platelets: how’s that relevant , 2012, Immunity & Ageing.
[122] L. Kuller,et al. Brain cholesterol metabolism, oxysterols, and dementia. , 2013, Journal of Alzheimer's disease : JAD.
[123] W. Klunk. Biological Markers of Alzheimer’s Disease , 1998, Neurobiology of Aging.
[124] P. Aisen,et al. A lead study on oxidative stress-mediated dehydroepiandrosterone formation in serum: the biochemical basis for a diagnosis of Alzheimer's disease. , 2011, Journal of Alzheimer's disease : JAD.
[125] C. Rowe,et al. Blood-Borne Amyloid-β Dimer Correlates with Clinical Markers of Alzheimer's Disease , 2010, The Journal of Neuroscience.
[126] K. Blennow,et al. Altered blood‐brain‐barrier function in Alzheimer's disease? , 1994, Acta neurologica Scandinavica.
[127] N. Roberts,et al. Increased absorption of aluminium from a normal dietary intake in dementia. , 1998, Journal of inorganic biochemistry.
[128] C. Rowe,et al. Plasma apolipoprotein E and Alzheimer disease risk , 2011, Neurology.
[129] Xianlin Han,et al. Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: molecular characterization using electrospray ionization mass spectrometry , 2001, Journal of neurochemistry.
[130] P. Mcgeer,et al. Inflammatory aspects of Alzheimer disease and other neurodegenerative disorders. , 2008, Journal of Alzheimer's disease : JAD.
[131] J. Beard,et al. Iron status and stores decline with age in Lewis rats. , 2000, The Journal of nutrition.
[132] David M Holtzman,et al. Identification and validation of novel CSF biomarkers for early stages of Alzheimer's disease , 2007, Proteomics. Clinical applications.
[133] Kevin F Krenitsky,et al. Peripheral ethanolamine plasmalogen deficiency: a logical causative factor in Alzheimer's disease and dementia Published, JLR Papers in Press, August 2, 2007. , 2007, Journal of Lipid Research.
[134] J. Touchon,et al. Combined measurement of PEDF, haptoglobin and tau in cerebrospinal fluid improves the diagnostic discrimination between alzheimer’s disease and other dementias , 2011, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
[135] H. Chertkow,et al. Aberrant profiles of native and oxidized glycoproteins in Alzheimer plasma , 2003, Proteomics.
[136] Sudha Seshadri,et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. , 2010, JAMA.
[137] M. Mullan,et al. Plasma microRNA biomarkers for detection of mild cognitive impairment , 2012, Aging.
[138] K. Nakagawa,et al. Amyloid β Induces Adhesion of Erythrocytes to Endothelial Cells and Affects Endothelial Viability and Functionality , 2011, Bioscience, biotechnology, and biochemistry.
[139] Regina Berretta,et al. Multivariate Protein Signatures of Pre-Clinical Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative (ADNI) Plasma Proteome Dataset , 2012, PloS one.
[140] Xianlin Han. Lipid alterations in the earliest clinically recognizable stage of Alzheimer's disease: implication of the role of lipids in the pathogenesis of Alzheimer's disease. , 2005, Current Alzheimer research.
[141] C. Gong,et al. Deregulation of sphingolipid metabolism in Alzheimer's disease , 2010, Neurobiology of Aging.
[142] A. Bush,et al. Metals and Alzheimer's disease. , 2006, Journal of Alzheimer's disease : JAD.
[143] Silva Hecimovic,et al. Phospholipids and Alzheimer’s Disease: Alterations, Mechanisms and Potential Biomarkers , 2013, International journal of molecular sciences.
[144] D. Aarsland,et al. A novel blood test for the early detection of Alzheimer's disease. , 2011, Journal of Alzheimer's disease : JAD.
[145] N. Delibaş,et al. Alterations of plasma magnesium, copper, zinc, iron and selenium concentrations and some related erythrocyte antioxidant enzyme activities in patients with Alzheimer's disease. , 2010, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.
[146] P. Pasqualetti,et al. Longitudinal prognostic value of serum “free” copper in patients with Alzheimer disease , 2009, Neurology.
[147] A. Roses,et al. The discovery and early validation of novel plasma biomarkers in mild-to-moderate Alzheimer's disease patients responding to treatment with rosiglitazone , 2008 .
[148] Simone Lista,et al. Blood and plasma-based proteomic biomarker research in Alzheimer's disease , 2013, Progress in Neurobiology.
[149] T. Suuronen,et al. Clusterin: A forgotten player in Alzheimer's disease , 2009, Brain Research Reviews.
[150] W. Markesbery,et al. Oxidative damage in mild cognitive impairment and early Alzheimer's disease , 2007, Journal of neuroscience research.
[151] H. Wiśniewski,et al. Plasma amyloid β‐peptide 1–42 and incipient Alzheimer's disease , 1999 .
[152] Monique Breteler,et al. Identifying Early Markers of Alzheimer's Disease using Quantitative Multiplex Proteomic Immunoassay Panels , 2009, Annals of the New York Academy of Sciences.
[153] W. D. Ehmann,et al. Imbalances of trace elements related to oxidative damage in Alzheimer's disease brain. , 1998, Neurotoxicology.
[154] George J. Brewer,et al. Subclinical Zinc Deficiency in Alzheimer’s Disease and Parkinson’s Disease , 2010, American journal of Alzheimer's disease and other dementias.
[155] E. Londos,et al. Metal Concentrations in Plasma and Cerebrospinal Fluid in Patients with Alzheimer’s Disease , 2008, Dementia and Geriatric Cognitive Disorders.
[156] N. Nalivaeva,et al. Lipid Rafts and Alzheimer’s Disease: Protein-Lipid Interactions and Perturbation of Signaling , 2012, Front. Physio..
[157] Mark R. Wilson,et al. Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity. , 2008, Molecular bioSystems.
[158] J. Potempa,et al. The serpin superfamily of proteinase inhibitors: structure, function, and regulation. , 1994, The Journal of biological chemistry.
[159] V. Mok,et al. Serum zinc is decreased in Alzheimer’s disease and serum arsenic correlates positively with cognitive ability , 2010, BioMetals.
[160] M. Shoji,et al. Plasma biomarkers of Alzheimer's disease , 2008, Current opinion in psychiatry.
[161] S. Younkin,et al. Serum creatinine levels correlate with plasma amyloid β protein , 2002 .
[162] P. E. Johnson,et al. Assessment of copper status: effect of age and gender on reference ranges in healthy adults. , 1993, Clinical chemistry.
[163] Albert Hofman,et al. Plasma clusterin and the risk of Alzheimer disease. , 2011, JAMA.
[164] Joseph B. Martin,et al. Phosphoethanolamine and ethanolamine are decreased in Alzheimer's disease and Huntington's disease , 1987, Brain Research.
[165] H. Hinterhuber,et al. Cerebrospinal fluid biomarkers for diagnosis of Alzheimer's disease: beta-amyloid(1-42), tau, phospho-tau-181 and total protein. , 2007, Drugs of today.
[166] N. Delibaş,et al. Malondialdehyde, superoxide dismutase, melatonin, iron, copper, and zinc blood concentrations in patients with Alzheimer disease: cross-sectional study. , 2002, Croatian medical journal.
[167] C. Batich,et al. In situ characterization and mapping of iron compounds in Alzheimer's disease tissue. , 2005, Journal of Alzheimer's disease : JAD.
[168] C. Patlak,et al. Fate of Cerebrospinal Fluid‐Borne Amyloid β‐Peptide: Rapid Clearance into Blood and Appreciable Accumulation by Cerebral Arteries , 1996, Journal of neurochemistry.
[169] D. Boudreau,et al. Statins in the prevention of dementia and Alzheimer's disease: A meta‐analysis of observational studies and an assessment of confounding , 2013, Pharmacoepidemiology and drug safety.
[170] Lello Zolla,et al. Blood-related proteomics. , 2010, Journal of proteomics.
[171] J. D. Robertson,et al. Copper, iron and zinc in Alzheimer's disease senile plaques , 1998, Journal of the Neurological Sciences.
[172] A. Passaro,et al. Trace elements and cognitive impairment: an elderly cohort study. , 2004, Archives of gerontology and geriatrics. Supplement.
[173] C. Holmes,et al. Systemic inflammation and Alzheimer's disease. , 2011, Biochemical Society transactions.
[174] Madhav Thambisetty,et al. Blood-based biomarkers of Alzheimer's disease: challenging but feasible. , 2010, Biomarkers in medicine.
[175] D. Praticò. The neurobiology of isoprostanes and Alzheimer's disease. , 2010, Biochimica et biophysica acta.
[176] K. Peter,et al. Amyloid Plaques Dissociate Pentameric to Monomeric C‐Reactive Protein: A Novel Pathomechanism Driving Cortical Inflammation in Alzheimer's Disease? , 2012, Brain pathology.
[177] Julie A. Wood,et al. Circulating plasmalogen levels and Alzheimer Disease Assessment Scale-Cognitive scores in Alzheimer patients. , 2010, Journal of psychiatry & neuroscience : JPN.
[178] Susan M Resnick,et al. Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease. , 2010, Archives of general psychiatry.
[179] J. Kaye,et al. F2-Isoprostanes as Biomarkers of Late-onset Alzheimer’s Disease , 2007, Journal of Molecular Neuroscience.
[180] L. Svennerholm,et al. Membrane Lipids in the Aging Human Brain , 1991, Journal of neurochemistry.
[181] M. Mattson,et al. Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[182] P. Rossini,et al. An observational study on the influence of the APOE-ε4 allele on the correlation between ‘free’ copper toxicosis and EEG activity in Alzheimer disease , 2008, Brain Research.
[183] C. Masters,et al. Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples , 2013, Acta Neuropathologica.
[184] A. Wallin,et al. Decreased myelin lipids in Alzheimer's disease and vascular dementia , 1989, Acta neurologica Scandinavica.
[185] H. Fukuyama,et al. Peripheral Aβ subspecies as risk biomarkers of Alzheimer's disease , 2008, Proceedings of the National Academy of Sciences.
[186] J. Becker,et al. Plasma amyloid levels and the risk of AD in normal subjects in the Cardiovascular Health Study , 2008, Neurology.
[187] F. Pfrieger,et al. Cholesterol homeostasis and function in neurons of the central nervous system , 2003, Cellular and Molecular Life Sciences CMLS.
[188] K. Blennow,et al. Plasma and CSF serpins in Alzheimer disease and dementia with Lewy bodies , 2007, Neurology.
[189] C. Cotman,et al. Thrombin Attenuates Neuronal Cell Death and Modulates Astrocyte Reactivity Induced by β‐Amyloid In Vitro , 1996, Journal of neurochemistry.
[190] K Yaffe,et al. Midlife cardiovascular risk factors and risk of dementia in late life , 2005, Neurology.
[191] Ashley I. Bush,et al. Therapeutics for Alzheimer’s disease based on the metal hypothesis , 2008, Neurotherapeutics.
[192] Magda Tsolaki,et al. A blood gene expression marker of early Alzheimer's disease. , 2013, Journal of Alzheimer's disease : JAD.
[193] M. Rattray,et al. Gene expression profiling in human neurodegenerative disease , 2012, Nature Reviews Neurology.
[194] Georg Kemmler,et al. Five out of 16 plasma signaling proteins are enhanced in plasma of patients with mild cognitive impairment and Alzheimer's disease , 2011, Neurobiology of Aging.
[195] R. D'Hooge,et al. Superoxide Dismutase Activity in Cerebrospinal Fluid of Patients with Dementia and Some Other Neurological Disorders , 1998, Alzheimer disease and associated disorders.
[196] R. Tibshirani,et al. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins , 2007, Nature Medicine.
[197] H. Tammen,et al. Peptidomic analysis of human blood specimens: Comparison between plasma specimens and serum by differential peptide display , 2005, Proteomics.
[198] P. Liao,et al. Proteomics analysis of plasma for potential biomarkers in the diagnosis of Alzheimer's disease , 2007, Proteomics. Clinical applications.
[199] Christian Humpel,et al. Identifying and validating biomarkers for Alzheimer's disease , 2011, Trends in biotechnology.
[200] L. Ferrucci,et al. Statins and serum cholesterol's associations with incident dementia and mild cognitive impairment , 2010, Journal of Epidemiology & Community Health.
[201] Blaine R. Roberts,et al. Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease , 2014, Alzheimer's & Dementia.
[202] R. E. Pitas,et al. Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain. , 1987, The Journal of biological chemistry.
[203] J. Trojanowski,et al. Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease. , 2002, Archives of neurology.
[204] Arroyo,et al. Serum zinc, copper, insulin and lipids in Alzheimer's disease epsilon 4 apolipoprotein E allele carriers* , 1999, European journal of clinical investigation.
[205] G. Siest,et al. Apolipoprotein E Polymorphisms and Concentration in Chronic Diseases and Drug Responses , 2000, Clinical chemistry and laboratory medicine.
[206] M. ChB.,et al. Neutrophil‐lymphocyte ratio as a prognostic factor in colorectal cancer , 2005, Journal of surgical oncology.
[207] H. Arai,et al. Amyloid β Levels in Human Red Blood Cells , 2012, PloS one.
[208] Blaine R. Roberts,et al. Longitudinal analysis of serum copper and ceruloplasmin in Alzheimer's disease. , 2013, Journal of Alzheimer's disease : JAD.
[209] S. Mirza,et al. Neutrophil lymphocyte ratio as a measure of systemic inflammation in prevalent chronic diseases in Asian population , 2012, International archives of medicine.
[210] J. Cheong,et al. Metal transporters in intestine and brain: their involvement in metal-associated neurotoxicities , 2007, Human & experimental toxicology.
[211] P. Rossini,et al. ‘Free’ copper in serum of Alzheimer’s disease patients correlates with markers of liver function , 2007, Journal of Neural Transmission.
[212] Hung Q. Dam,et al. Blood Volume Analysis: A New Technique and New Clinical Interest Reinvigorate a Classic Study* , 2007, Journal of Nuclear Medicine Technology.
[213] K. Blennow,et al. Zinc and copper modulate Alzheimer Aβ levels in human cerebrospinal fluid , 2009, Neurobiology of Aging.
[214] R. Mayeux,et al. Meta-analysis of plasma amyloid-β levels in Alzheimer's disease. , 2011, Journal of Alzheimer's disease : JAD.
[215] B. Hyman,et al. The normal equilibrium between CSF and plasma amyloid beta levels is disrupted in Alzheimer's disease , 2007, Neuroscience Letters.
[216] V. Leoni. Oxysterols as markers of neurological disease – a review , 2009, Scandinavian journal of clinical and laboratory investigation.
[217] P. Tessari,et al. High Abundance Proteins Depletion vs Low Abundance Proteins Enrichment: Comparison of Methods to Reduce the Plasma Proteome Complexity , 2011, PloS one.
[218] H. Soininen,et al. Plasma Aβ42 and Aβ40 as markers of cognitive change in follow-up: a prospective, longitudinal, population-based cohort study , 2010, Journal of Neurology, Neurosurgery & Psychiatry.
[219] P. Pasqualetti,et al. Elevation of serum copper levels in Alzheimer’s disease , 2002, Neurology.
[220] B. Winblad,et al. Metals and trace elements in plasma and cerebrospinal fluid in normal aging and Alzheimer's disease. , 1991, Journal of neural transmission. Parkinson's disease and dementia section.
[221] Y. Oda,et al. Identification of a new plasma biomarker of Alzheimer's disease using metabolomics technology[S] , 2012, Journal of Lipid Research.
[222] A. Lewis. The role of copper in inflammatory disorders , 1984, Agents and Actions.
[223] R. Mahley,et al. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. , 1988, Science.
[224] D. Elliott,et al. Isoform-specific proteolysis of apolipoprotein-E in the brain , 2011, Neurobiology of Aging.
[225] S. Younkin,et al. Plasma amyloid β protein is elevated in late-onset Alzheimer disease families , 2008, Neurology.
[226] Kevin Taddei,et al. Increased plasma apolipoprotein E (apoE) levels in Alzheimer's disease , 1997, Neuroscience Letters.
[227] D. DeMets,et al. Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework , 2001, Clinical pharmacology and therapeutics.
[228] I. Ferrier,et al. Gastrointestinal absorption of aluminium in Alzheimer's disease: response to aluminium citrate. , 1992, Age and ageing.
[229] Andrew F. Hill,et al. Exosomes: Vehicles for the Transfer of Toxic Proteins Associated with Neurodegenerative Diseases? , 2012, Front. Physio..
[230] R. Mayeux,et al. Plasma ß-amyloid and cognitive decline. , 2010, Archives of neurology.
[231] F. Giubilei,et al. Monitoring of chemical elements and oxidative damage in patients affected by Alzheimer's disease. , 2005, Annali dell'Istituto superiore di sanita.
[232] M. Ferretti,et al. Does a pro-inflammatory process precede Alzheimer's disease and mild cognitive impairment? , 2011, Current Alzheimer research.
[233] Irma-Leena Notkola,et al. Serum Total Cholesterol, Apolipoprotein E {FC12}e4 Allele, and Alzheimer’s Disease , 1998, Neuroepidemiology.
[234] Walter J Koroshetz,et al. Plasma biomarkers associated with the apolipoprotein E genotype and Alzheimer disease. , 2012, Archives of neurology.
[235] Lars-Olof Wahlund,et al. Structural and Quantitative Comparison of Cerebrospinal Fluid Glycoproteins in Alzheimer’s Disease Patients and Healthy Individuals , 2008, Neurochemical Research.
[236] Dominique Drouin,et al. Toward an Alzheimer's disease diagnosis via high-resolution blood gene expression , 2010, Alzheimer's & Dementia.
[237] Norman J Beauchamp,et al. White Matter Hyperintensity on Cranial Magnetic Resonance Imaging: A Predictor of Stroke , 2004, Stroke.
[238] R. Kalaria,et al. Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease. , 1992, Neuroreport.
[239] L. Launer,et al. Do red blood cell-beta-amyloid interactions alter oxygen delivery in Alzheimer's disease? , 2008, Advances in experimental medicine and biology.
[240] D. Selkoe,et al. Amyloid β-peptide is produced by cultured cells during normal metabolism , 1992, Nature.
[241] S. Rapoport,et al. Disease and anatomic specificity of ethanolamine plasmalogen deficiency in Alzheimer's disease brain , 1995, Brain Research.
[242] Arch G Mainous,et al. Cholesterol, transferrin saturation, and the development of dementia and Alzheimer's disease: results from an 18-year population-based cohort. , 2005, Family medicine.
[243] Z. A. Oztürk,et al. The Evaluation of Neutrophil-Lymphocyte Ratio in Alzheimer’s Disease , 2012, Dementia and Geriatric Cognitive Disorders.
[244] S. Rapoport,et al. Disturbed choline plasmalogen and phospholipid fatty acid concentrations in Alzheimer's disease prefrontal cortex. , 2011, Journal of Alzheimer's disease : JAD.
[245] T. Okazaki,et al. Analysis of the affinity of each haptoglobin polymer for hemoglobin by two-dimensional affinity electrophoresis. , 1997, Clinica chimica acta; international journal of clinical chemistry.
[246] S. Scott,et al. Cathepsin D-mediated proteolysis of apolipoprotein E: Possible role in Alzheimer’s disease , 2006, Neuroscience.
[247] E. Zimmerman,et al. Copper and Ceruloplasmin Abnormalities in Alzheimer’s Disease , 2010, American journal of Alzheimer's disease and other dementias.
[248] N. Herrmann,et al. A Meta-Analysis of Cytokines in Alzheimer's Disease , 2010, Biological Psychiatry.
[249] N. Arnal,et al. Clinical utility of copper, ceruloplasmin, and metallothionein plasma determinations in human neurodegenerative patients and their first-degree relatives , 2010, Brain Research.
[250] W. D. Ehmann,et al. Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress , 1996, Journal of the Neurological Sciences.
[251] D. Holtzman,et al. Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. , 2000, The Journal of clinical investigation.
[252] Hilkka Soininen,et al. Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. , 2005, Archives of neurology.
[253] R. Tanzi,et al. Twenty Years of the Alzheimer’s Disease Amyloid Hypothesis: A Genetic Perspective , 2005, Cell.
[254] J. Kaye,et al. Safety and Acceptability of the Research Lumbar Puncture , 2005, Alzheimer disease and associated disorders.
[255] David R. Willé,et al. Proteomic identification and early validation of complement 1 inhibitor and pigment epithelium‐derived factor: Two novel biomarkers of Alzheimer's disease in human plasma , 2008, Proteomics. Clinical applications.