A computer program to derive the rate equations of enzyme catalysed reactions with up to ten enzyme-containing intermediates in the reaction mechanism.

The paper describes a program, designed for a desk-top computer, which can be used to derive the rate equations of enzyme catalysed reactions with up to ten enzyme-containing intermediates included in the mechanism. The program allows the rate equation to be presented in simplified forms of practical use and in a variety of formats.

[1]  S Ainsworth The mechanistic interpretation of initial velocity and product inhibition data arising from enzyme catalysed reactions whose catalytic cycle is unbranched. , 1975, Journal of theoretical biology.

[2]  S Ainsworth A slide rule for deriving the rate equations of enzyme catalysed reactions with mechanisms involving up to six enzyme-containing intermediates. , 1974, Journal of theoretical biology.

[3]  S Ainsworth,et al.  The derivation of second degree rate equations arising from two-substrate, two-product enzyme catalysed reactions whose catalytic cycle is branched. , 1976, International journal of bio-medical computing.

[4]  E. L. King,et al.  A Schematic Method of Deriving the Rate Laws for Enzyme-Catalyzed Reactions , 1956 .

[5]  R O Hurst A computer program for writing the steady-state rate equation for a multisubstrate enzymic reaction. , 1969, Canadian journal of biochemistry.

[6]  Britton Chance,et al.  Studies on Liver Alcohol Dehydrogenase. II. The Kinetics of the Compound of Horse Liver Alcohol Dehydrogenase and Reduced Diphosphopyridine Nucleotide. , 1951 .

[7]  S. Cha A simple method for derivation of rate equations for enzyme-catalyzed reactions under the rapid equilibrium assumption or combined assumptions of equilibrium and steady state. , 1968, The Journal of biological chemistry.

[8]  A R Schulz,et al.  Computer-based derivation and reformulation of enzyme reaction models. , 1970, International journal of bio-medical computing.