Childhood poverty, chronic stress, and adult working memory

The income–achievement gap is a formidable societal problem, but little is known about either neurocognitive or biological mechanisms that might account for income-related deficits in academic achievement. We show that childhood poverty is inversely related to working memory in young adults. Furthermore, this prospective relationship is mediated by elevated chronic stress during childhood. Chronic stress is measured by allostatic load, a biological marker of cumulative wear and tear on the body that is caused by the mobilization of multiple physiological systems in response to chronic environmental demands.

[1]  N. Adler,et al.  U.S. disparities in health: descriptions, causes, and mechanisms. , 2008, Annual review of public health.

[2]  M. Donnellan,et al.  An interactionist perspective on the socioeconomic context of human development. , 2007, Annual review of psychology.

[3]  S. Lupien,et al.  The effects of stress and stress hormones on human cognition: Implications for the field of brain and cognition , 2007, Brain and Cognition.

[4]  Andrew D. Martin,et al.  Trajectories of Socioeconomic Status Across Children's Lifetime Predict Health , 2007, Pediatrics.

[5]  Bruce D. McCandliss,et al.  Socioeconomic gradients predict individual differences in neurocognitive abilities. , 2007, Developmental science.

[6]  Virginia F. Cutler,et al.  Childhood Poverty and Health Cumulative Risk Exposure and Stress Dysregulation , 2007 .

[7]  M. Farah,et al.  Childhood poverty: Specific associations with neurocognitive development , 2006, Brain Research.

[8]  J. Heckman Skill Formation and the Economics of Investing in Disadvantaged Children , 2006, Science.

[9]  Toni,et al.  An End to Stress , 2006 .

[10]  J. Belsky,et al.  Duration and developmental timing of poverty and children's cognitive and social development from birth through third grade. , 2005, Child development.

[11]  M. Farah,et al.  Neurocognitive correlates of socioeconomic status in kindergarten children. , 2005, Developmental science.

[12]  Alexander Bucur,et al.  Cumulative biological risk and socio-economic differences in mortality: MacArthur studies of successful aging. , 2004, Social science & medicine.

[13]  Joseph E LeDoux The Emotional Brain, Fear, and the Amygdala , 2003, Cellular and Molecular Neurobiology.

[14]  B. Singer,et al.  Allostatic load as a predictor of functional decline. MacArthur studies of successful aging. , 2002, Journal of clinical epidemiology.

[15]  G. Evans,et al.  The environment of poverty: multiple stressor exposure, psychophysiological stress, and socioemotional adjustment. , 2002, Child development.

[16]  K. Matthews,et al.  Socioeconomic differences in children's health: how and why do these relationships change with age? , 2002, Psychological bulletin.

[17]  B. McEwen,et al.  The end of stress as we know it , 2002 .

[18]  R. Bradley,et al.  Socioeconomic status and child development. , 2002, Annual review of psychology.

[19]  J W Rowe,et al.  Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[20]  P. O’Campo,et al.  Securing the Future: Investing in Children from Birth to College , 2002 .

[21]  Bruce S. McEwen,et al.  The neurobiology of stress: from serendipity to clinical relevance. , 2000, Brain research.

[22]  B. McEwen,et al.  Child’s stress hormone levels correlate with mother’s socioeconomic status and depressive state , 2000, Biological Psychiatry.

[23]  D. Phillips,et al.  From Neurons to Neighborhoods: The Science of Early Childhood Development , 2000 .

[24]  Rockville National Institute of Child Health and Human Development Early Child Care Research Network. , 2002 .

[25]  T. Seeman,et al.  Protective and Damaging Effects of Mediators of Stress: Elaborating and Testing the Concepts of Allostasis and Allostatic Load , 1999, Annals of the New York Academy of Sciences.

[26]  C. Power,et al.  The duration and timing of exposure: effects of socioeconomic environment on adult health. , 1999, American journal of public health.

[27]  R. Hauger,et al.  Working memory is more sensitive than declarative memory to the acute effects of corticosteroids: a dose-response study in humans. , 1999, Behavioral neuroscience.

[28]  E E Smith,et al.  Components of verbal working memory: evidence from neuroimaging. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[29]  V. Mcloyd,et al.  Socioeconomic disadvantage and child development. , 1998, The American psychologist.

[30]  B. McEwen Protective and damaging effects of stress mediators. , 1998, The New England journal of medicine.

[31]  J. Lynch,et al.  Cumulative impact of sustained economic hardship on physical, cognitive, psychological, and social functioning. , 1997, The New England journal of medicine.

[32]  B. Singer,et al.  Price of adaptation--allostatic load and its health consequences. MacArthur studies of successful aging. , 1997, Archives of internal medicine.

[33]  M Spitzer,et al.  [Stress and cognition]. , 1996, Medizinische Monatsschrift fur Pharmazeuten.

[34]  C. Patterson,et al.  Environmental risk factors and children's achievement from middle childhood to early adolescence. , 1996 .

[35]  David R. Williams,et al.  Us socioeconomic and racial differences in health: patterns and explanations , 1995 .

[36]  S. Korenman,et al.  Long-term poverty and child development in the United States: Results from the NLSY , 1995 .

[37]  T. Kamarck,et al.  Reliable measures of behaviorally-evoked cardiovascular reactivity from a PC-based test battery: results from student and community samples. , 1992, Psychophysiology.

[38]  L. N. Contreras,et al.  Urinary cortisol in the assessment of pituitary-adrenal function: utility of 24-hour and spot determinations. , 1986, The Journal of clinical endocrinology and metabolism.

[39]  Bethany J Figg,et al.  National Institute of Child Health and Human Development , 2013 .

[40]  P. Kissinger,et al.  Determination of catecholamines in urine by reverse-phase liquid chromatography with electrochemical detection. , 1977, Analytical chemistry.