Nicotine stimulates the expression of cyclooxygenase-2 mRNA via NFkappaB activation in human gingival fibroblasts.

[1]  J. Bradley,et al.  TNF‐mediated inflammatory disease , 2008, The Journal of pathology.

[2]  L. Ulloa,et al.  The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation , 2007, British journal of pharmacology.

[3]  G. K. Johnson,et al.  The impact of cigarette smoking on periodontal disease and treatment. , 2007, Periodontology 2000.

[4]  B. Olson,et al.  Nicotine and lipopolysaccharide affect cytokine expression from gingival fibroblasts. , 2007, Journal of periodontology.

[5]  K. Pinkerton,et al.  Receptor‐mediated tobacco toxicity: cooperation of the Ras/Raf‐1/MEK1/ERK and JAK‐2/STAT‐3 pathways downstream of a7 nicotinic receptor in oral keratinocytes , 2006 .

[6]  E. Mazzon,et al.  Pyrrolidine dithiocarbamate reduced experimental periodontitis. , 2006, European journal of pharmacology.

[7]  Yu-Chao Chang,et al.  Regulation of nicotine-induced cyclooxygenase-2 protein expression in human gingival fibroblasts , 2006, Acta Pharmacologica Sinica.

[8]  P. Celec Nuclear factor kappa B--molecular biomedicine: the next generation. , 2004, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[9]  Yoshifumi Yamamoto,et al.  Platelet‐derived growth factor‐induced arachidonic acid release for enhancement of prostaglandin E2 synthesis in human gingival fibroblasts pretreated with interleukin‐1β , 2004, Journal of cellular biochemistry.

[10]  M. Yamazaki,et al.  Tumor necrosis factor α (TNF-α)-induced prostaglanding E2 release is mediated by the activation of cyclooxygenase-2 (COX-2)transcription via NFκB in human gingival fibroblasts , 2002, Molecular and Cellular Biochemistry.

[11]  M. Yamazaki,et al.  Activation of NFκB is necessary for IL-1β-induced cyclooxygenase-2 (COX-2) expression in human gingival fibroblasts , 2000, Molecular and Cellular Biochemistry.

[12]  M. Chou,et al.  Induction of cyclooxygenase-2 mRNA and protein expression in human gingival fibroblasts stimulated with nicotine. , 2003, Journal of periodontal research.

[13]  B. Aggarwal,et al.  Cigarette smoke condensate activates nuclear transcription factor-κB through phosphorylation and degradation of IκBα: correlation with induction of cyclooxygenase-2 , 2002 .

[14]  S. Stein,et al.  Regulation of cytokine production in human gingival fibroblasts following treatment with nicotine and lipopolysaccharide. , 2001, Journal of periodontology.

[15]  H. Sugiya,et al.  Bradykinin potentiates prostaglandin E(2) release in the human gingival fibroblasts pretreated with interleukin-1beta via Ca(2+) mobilization. , 2000, European journal of pharmacology.

[16]  C. Cutler,et al.  Clinical benefits of oral irrigation for periodontitis are related to reduction of pro-inflammatory cytokine levels and plaque. , 2000, Journal of clinical periodontology.

[17]  S. Eliasson,et al.  Exposure to tobacco smoking and periodontal health. , 2000, Journal of clinical periodontology.

[18]  R. Garavito,et al.  Cyclooxygenases: structural, cellular, and molecular biology. , 2000, Annual review of biochemistry.

[19]  N. Sayers,et al.  Effects of tobacco products on the attachment and growth of periodontal ligament fibroblasts. , 1999, Journal of periodontology.

[20]  M. Takano,et al.  Distinct characteristics of transcellular transport between nicotine and tetraethylammonium in LLC-PK1 cells. , 1998, The Journal of pharmacology and experimental therapeutics.

[21]  K. Giacomini,et al.  Nicotine transport in a human choriocarcinoma cell line (JAR). , 1998, Journal of pharmaceutical sciences.

[22]  M. Cattaneo,et al.  Mechanisms of mitogen-activated protein kinase activation by nicotine in small-cell lung carcinoma cells. , 1997, The Biochemical journal.

[23]  D. Tipton,et al.  Effects of nicotine on proliferation and extracellular matrix production of human gingival fibroblasts in vitro. , 1995, Journal of periodontology.

[24]  P. De Koninck,et al.  Agonist and toxin sensitivities of ACh-evoked currents on neurons expressing multiple nicotinic ACh receptor subunits. , 1995, Journal of neurophysiology.

[25]  K. Matsushima,et al.  The IL‐1 receptor signaling pathway , 1994, Journal of leukocyte biology.

[26]  I. Mandel,et al.  Smoke signals: an alert for oral disease. , 1994, Journal of the American Dental Association.

[27]  T. Hla,et al.  Human cyclooxygenase-2 cDNA. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[28]  M. Smith,et al.  Effects of NSAIDs on beagle crevicular cyclooxygenase metabolites and periodontal bone loss. , 1992, Journal of periodontal research.

[29]  R. Kent,et al.  Cigarette smoking in a periodontal practice. , 1992, Journal of periodontology.

[30]  P. Hanes,et al.  Binding, uptake, and release of nicotine by human gingival fibroblasts. , 1991, Journal of periodontology.

[31]  G. R. Imm,et al.  A Comparative Study of Human Periodontal Ligament Cells and Gingival Fibroblasts in vitro , 1988, Journal of dental research.

[32]  K. Fujimori,et al.  Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers. , 1987, Cancer research.

[33]  S. Offenbacher,et al.  The use of crevicular fluid prostaglandin E2 levels as a predictor of periodontal attachment loss. , 1986, Journal of periodontal research.

[34]  S. Offenbacher,et al.  Crevicular fluid prostaglandin E levels as a measure of the periodontal disease status of adult and juvenile periodontitis patients. , 1984, Journal of periodontal research.

[35]  M. M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.