Speed of lower-level auditory and visual processing as a basic factor in dyslexia: Electrophysiological evidence

This study investigated speed of processing (SOP) among college-level adult dyslexic and normal readers in nonlinguistic and sublexical linguistic auditory and visual oddball tasks, and a nonlinguistic cross-modal choice reaction task. Behavioral and electrophysiological (ERP) measures were obtained. The results revealed that between both groups, reaction times (RT) were longer and the latencies of P2 and P3 components occurred later in the visual as compared to auditory oddball tasks. RT and ERP latencies were longest in the cross-modal task. RT and ERP latencies were delayed among dyslexic as compared to normal readers across tasks. On the oddball tasks, group differences in brain activity were observed only when responding to low-probability targets. These differences were largest for the P3 component, and most pronounced in the case of phonemes. The gap between ERP latencies in the visual versus the auditory modalities for each component was larger among dyslexic as compared to normal readers, and was particularly evident at the linguistic level. A hypothesis is proposed that suggests an amodal, basic SOP deficit among dyslexic readers. The slower cross-modal SOP is attributed to slower information processing in general and to disproportionate "asynchrony" between SOP in the visual versus the auditory system. It is suggested that excessive asynchrony in the SOP of the two systems may be one of the underlying causes of dyslexics' impaired reading skills.

[1]  R. Johnson.  A triarchic model of P300 amplitude. , 1986, Psychophysiology.

[2]  J. Polich,et al.  P300 topography and modality effects from a single-stimulus paradigm. , 1996, Psychophysiology.

[3]  F. Wood,et al.  Neuropsychological profile of adult dyslexics , 1990, Brain and Language.

[4]  S. Hillyard,et al.  Cross-modal selective attention effects on retinal, myogenic, brainstem, and cerebral evoked potentials. , 1990, Psychophysiology.

[5]  M. Studdert-Kennedy,et al.  Auditory temporal perception deficits in the reading-impaired: A critical review of the evidence , 1995, Psychonomic bulletin & review.

[6]  Zvia Breznitz,et al.  Enhancing the reading of dyslexic children by reading acceleration and auditory masking , 1997 .

[7]  J. Stein.  Developmental dyslexia, neural timing and hemispheric lateralisation. , 1994, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[8]  Marta Kutas,et al.  Electrophysiological insights into language deficits , 1995 .

[9]  W. D. Weirdt.  Speech perception and frequency discrimination in good and poor readers , 1988, Applied Psycholinguistics.

[10]  J. Raven.  Advanced progressive matrices : sets I and II , 1962 .

[11]  M. Taylor,et al.  Event-related potentials to visual and language stimuli in normal and dyslexic children. , 1990, Psychophysiology.

[12]  U. Frith,et al.  Explicit and implicit processing of words and pseudowords by adult developmental dyslexics: A search for Wernicke's Wortschatz? , 1999, Brain : a journal of neurology.

[13]  M. Reed.  Speech perception and the discrimination of brief auditory cues in reading disabled children. , 1989, Journal of experimental child psychology.

[14]  H G Vaughan,et al.  Manipulation of event-related potential manifestations of information processing stages. , 1982, Science.

[15]  N. Ellis.  Reading Development, Dyslexia and Phonological Skills , 1989 .

[16]  R. Klein,et al.  The evidence for a temporal processing deficit linked to dyslexia: A review , 1995, Psychonomic bulletin & review.

[17]  Marilyn Jager Adams,et al.  Beginning To Read: Thinking and Learning about Print. , 1991 .

[18]  C Witton,et al.  Monaural and binaural detection of sinusoidal phase modulation of a 500-Hz tone. , 2000, The Journal of the Acoustical Society of America.

[19]  I. S. Brown,et al.  Phonological processes as predictors of specific reading skills in children at risk for reading failure , 1990 .

[20]  David J Heeger,et al.  Psychophysical evidence for a magnocellular pathway deficit in dyslexia , 1998, Vision Research.

[21]  Terence W. Picton,et al.  Event-related potentials recorded during the discrimination of improbable stimuli , 1983, Biological Psychology.

[22]  H. Neville,et al.  The Neurobiology of Sensory and Language Processing in Language-Impaired Children , 1993, Journal of Cognitive Neuroscience.

[23]  T W Picton,et al.  N2 and automatic versus controlled processes. , 1986, Electroencephalography and clinical neurophysiology. Supplement.

[24]  Patricia Greig Bowers,et al.  Theoretical links among naming speed, precise timing mechanisms and orthographic skill in dyslexia , 1993 .

[25]  J. Polich,et al.  Task difficulty, probability, and inter-stimulus interval as determinants of P300 from auditory stimuli. , 1987, Electroencephalography and clinical neurophysiology.

[26]  R Hari,et al.  Auditory stream segregation in dyslexic adults. , 1999, Brain : a journal of neurology.

[27]  S. Luck,et al.  Electrophysiological correlates of feature analysis during visual search. , 1994, Psychophysiology.

[28]  R. Klein,et al.  Auditory and Visual Temporal Processing in Dyslexic and Normal Readers , 1993, Annals of the New York Academy of Sciences.

[29]  G. Mangun,et al.  Developmental dyslexia: Passive visual stimulation provides no evidence for a magnocellular processing defect , 1996, Neuropsychologia.

[30]  A. Fawcett,et al.  Reaction Times and Dyslexia , 1994, The Quarterly journal of experimental psychology. A, Human experimental psychology.

[31]  M. Snowling.  Phonological processing and developmental dyslexia , 1995 .

[32]  R. Oades,et al.  Development and topography of auditory event-related potentials (ERPs): mismatch and processing negativity in individuals 8-22 years of age. , 1997, Psychophysiology.

[33]  P. F. Jong.  Working Memory Deficits of Reading Disabled Children , 1998 .

[34]  H. Jasper,et al.  The ten-twenty electrode system of the International Federation. The International Federation of Clinical Neurophysiology. , 1999, Electroencephalography and clinical neurophysiology. Supplement.

[35]  A. Galaburda,et al.  Evidence for aberrant auditory anatomy in developmental dyslexia. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[36]  C. Boden,et al.  Visual Processing of Verbal and Nonverbal Stimuli in Adolescents with Reading Disabilities , 1999, Journal of learning disabilities.

[37]  J. Stein,et al.  Auditory temporal coding in dyslexia , 1996, Proceedings of the Royal Society of London. Series B: Biological Sciences.

[38]  D. Heeger,et al.  Functional Magnetic Resonance Imaging of Early Visual Pathways in Dyslexia , 1998, The Journal of Neuroscience.

[39]  N. Drasdo,et al.  The magnocellular deficit hypothesis in dyslexia: a review of reported evidence. , 1995, Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians.

[40]  T W Picton,et al.  ON and OFF components in the auditory evoked potential , 1978, Perception & psychophysics.

[41]  A. Galaburda.  Neuroanatomic basis of developmental dyslexia. , 1993, Neurologic clinics.

[42]  N. Squires,et al.  The effect of stimulus sequence on the waveform of the cortical event-related potential. , 1976, Science.

[43]  Y. Zhuo,et al.  Modulation of Brain Activities by Hierarchical Processing: A High-Density ERP Study , 2004, Brain Topography.

[44]  Victor H. P. van Daal,et al.  Automatization Aspects of Dyslexia Speed Limitations in Word Identification, Sensitivity to Increasing Task Demands, and Orthographic Compensation , 1999 .

[45]  H. Pratt,et al.  Brain potentials from dyslexic children recorded during short-term memory tasks. , 1994, The International journal of neuroscience.

[46]  Michael G. H. Coles,et al.  Advances in psychophysiology : a research annual , 1985 .

[47]  H Lyytinen,et al.  Auditory event-related potentials in the study of developmental language-related disorders. , 1997, Audiology & neuro-otology.

[48]  W. Lovegrove,et al.  Visual temporal processing deficits in specific reading disability. , 1993 .

[49]  H G Vaughan,et al.  Differentiation of negative event-related potentials in an auditory discrimination task. , 1990, Electroencephalography and clinical neurophysiology.

[50]  Jordan Grafman,et al.  Handbook of Neuropsychology , 1991 .

[51]  C. Warren,et al.  Event-related potentials in a guessing task: the gleam in the eye effect. , 1992, The International journal of neuroscience.

[52]  M. Kutas,et al.  Ambiguous words in context: An event-related potential analysis of the time course of meaning activation ☆ ☆☆ , 1987 .

[53]  C Casco,et al.  Visual Search of Good and Poor Readers: Effects with Targets Having Single and Combined Features , 1996, Perceptual and motor skills.

[54]  M. Studdert-Kennedy,et al.  Speech perception deficits in poor readers: auditory processing or phonological coding? , 1997, Journal of experimental child psychology.

[55]  Evelyne Corcos,et al.  Visual Processes in Reading and Reading Disabilities , 1993 .

[56]  H. Lee Swanson,et al.  Cognitive processes as predictors of word recognition and reading comprehension in learning-disabled and skilled readers: Revisiting the specificity hypothesis. , 1997 .

[57]  James L. McClelland,et al.  A distributed, developmental model of word recognition and naming. , 1989, Psychological review.

[58]  F. Wood,et al.  I. Separate brain potential characteristics in children with reading disability and attention deficit disorder: Relevance-independent effects , 1988, Brain and Cognition.

[59]  Paula Tallal,et al.  Perceptual/motor profiles of reading impaired children with or without concomitant oral language deficits , 1982 .

[60]  S Sutton,et al.  P300 and slow wave in a message consisting of two events. , 1982, Psychophysiology.

[61]  M. Bruck,et al.  Do Adult Dyslexics Show Low‐level Visual Processing Deficits? , 1993, Annals of the New York Academy of Sciences.

[62]  A. Fawcett,et al.  Event‐related Potentials and Dyslexia , 1993, Annals of the New York Academy of Sciences.

[63]  E. Donchin,et al.  Probability effects on stimulus evaluation and response processes. , 1992, Journal of experimental psychology. Human perception and performance.

[64]  P. Tallal.  Auditory temporal perception, phonics, and reading disabilities in children , 1980, Brain and Language.

[65]  L. Anllo-Vento,et al.  II. Separate brain potential characteristics in children with reading disability and attention deficit disorder: Color and letter relevance effects , 1988, Brain and Cognition.

[66]  K. Squires,et al.  Variations in early and late event-related components of the auditory evoked potential with task difficulty. , 1983, Electroencephalography and clinical neurophysiology.

[67]  Zvia Breznitz,et al.  Speed of processing of the visual–orthographic and auditory–phonological systems in adult dyslexics: The contribution of “asynchrony” to word recognition deficits , 2003, Brain and Language.

[68]  E. Lambe.  Dyslexia, gender, and brain imaging , 1999, Neuropsychologia.

[69]  P. Holcomb,et al.  Auditory event-related potentials in attention and reading disabled boys. , 1986, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[70]  Richard J. Davidson,et al.  Evoked potential measures of interhemispheric transfer time in reading disabled and normal boys , 1992 .

[71]  H. Pratt,et al.  Auditory event-related potentials among dyslexic and normal-reading children: 3CLT and midline comparisons. , 1992, The International journal of neuroscience.

[72]  M. Coles,et al.  Handbook of cognitive psychophysiology : central and autonomic nervous system approaches , 1991 .

[73]  J. Polich,et al.  P300, handedness, and corpus callosal size: gender, modality, and task. , 1999, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[74]  Riitta Hari,et al.  Deficit of temporal auditory processing in dyslexic adults , 1996, Neuroscience Letters.

[75]  Eleanor J. Gibson,et al.  Learning to read , 1965, Science.

[76]  J. A. Baro,et al.  A defective visual pathway in children with reading disability. , 1993, The New England journal of medicine.

[77]  R. Wagner,et al.  The nature of phonological processing and its causal role in the acquisition of reading skills. , 1987 .

[78]  M. Bruck.  Word-Recognition Skills of Adults with Childhood Diagnoses of Dyslexia. , 1990 .

[79]  W. Ridder,et al.  The presence of a magnocellular defect depends on the type of dyslexia , 1996, Vision Research.

[80]  R Llinás,et al.  Is Dyslexia a Dyschronia? , 1993, Annals of the New York Academy of Sciences.

[81]  Shlomo Bentin,et al.  Event-related potentials, semantic processes, and expectancy factors in word recognition , 1987, Brain and Language.

[82]  V. Mann,et al.  Reading disability: the role of language deficiencies. , 1988, Journal of consulting and clinical psychology.

[83]  Emanuel Donchin,et al.  The P300 component of the event-related brain potential as an index of information processing , 1982, Biological Psychology.

[84]  H. Swanson,et al.  Learning-disabled readers' working memory as a function of processing demands. , 1996, Journal of experimental child psychology.

[85]  Bruce R. Dunn,et al.  The Relation of ERP Components to Complex Memory Processing , 1998, Brain and Cognition.

[86]  P. H. Lindsay,et al.  Evoked Potential Correlates of Auditory Signal Detection , 1971, Science.

[87]  A. Kramer,et al.  Task versus component consistency in the development of automatic processing: a psychophysiological assessment. , 1991, Psychophysiology.

[88]  A. Fawcett,et al.  Children with Dyslexia Classify Pure Tones Slowly , 1993, Annals of the New York Academy of Sciences.

[89]  J. Cohen,et al.  On the number of trials needed for P300. , 1997, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[90]  R. Thatcher.  Developmental neuroimaging : mapping the development of brain and behavior , 1996 .

[91]  R. L. McCroskey,et al.  Auditory Fusion among Learning Disabled, Reading Disabled, and Normal Children , 1980, Journal of learning disabilities.

[92]  G. McCarthy,et al.  Language-related field potentials in the anterior-medial temporal lobe: II. Effects of word type and semantic priming , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[93]  Topography of auditory evoked cortical potentials in children with severe language impairment. , 1996, Scandinavian audiology. Supplementum.

[94]  P. Holcomb,et al.  Cognitive event-related brain potentials in children with attention and reading deficits. , 1985, Psychophysiology.

[95]  R. Hari,et al.  Modulation of the Parieto-Occipital Alpha Rhythm during Object Detection , 1997, The Journal of Neuroscience.

[96]  Carsten Elbro,et al.  Dyslexia in adults: Evidence for deficits in non-word reading and in the phonological representation of lexical items , 1994, Annals of dyslexia.

[97]  B. Pennington,et al.  Spelling errors and reading fluency in compensated adult dyslexics , 1991, Annals of dyslexia.

[98]  K. Stanovich,et al.  Phenotypic performance profile of children with reading disabilities: A regression-based test of the phonological-core variable-difference model. , 1994 .

[99]  Children with Dyslexia Automatize Temporal Skills More Slowly , 1993, Annals of the New York Academy of Sciences.

[100]  P. Wolff,et al.  Impaired Temporal Resolution in Developmental Dyslexia a , 1993, Annals of the New York Academy of Sciences.

[101]  R. Woods,et al.  Abnormal processing of visual motion in dyslexia revealed by functional brain imaging , 1996, Nature.